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Protein

60S ribosomal protein L27a

Gene

RpL27A

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cytoplasmic translation Source: FlyBase

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-DME-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-DME-1799339 SRP-dependent cotranslational protein targeting to membrane
R-DME-72689 Formation of a pool of free 40S subunits
R-DME-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-DME-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-DME-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L27a
Gene namesi
Name:RpL27A
Synonyms:RpL27a2, RpL27Aa, RpL27Ab
ORF Names:CG15442
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2L

Organism-specific databases

FlyBaseiFBgn0285948 RpL27A

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001048861 – 14960S ribosomal protein L27aAdd BLAST149

Proteomic databases

PaxDbiP41092
PRIDEiP41092

Expressioni

Gene expression databases

BgeeiFBgn0261606
GenevisibleiP41092 DM

Interactioni

Protein-protein interaction databases

BioGridi59848, 4 interactors
DIPiDIP-18398N
IntActiP41092, 23 interactors
STRINGi7227.FBpp0077142

Structurei

3D structure databases

ProteinModelPortaliP41092
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1742 Eukaryota
COG0200 LUCA
GeneTreeiENSGT00390000005534
InParanoidiP41092
KOiK02900
OMAiGRVGQHR
OrthoDBiEOG091G0TQF
PhylomeDBiP41092

Family and domain databases

HAMAPiMF_01341 Ribosomal_L15, 1 hit
InterProiView protein in InterPro
IPR036227 L18e/L15P_sf
IPR030878 Ribosomal_L15
IPR001196 Ribosomal_L15_CS
IPR021131 Ribosomal_L18e/L15P
PfamiView protein in Pfam
PF00828 Ribosomal_L27A, 1 hit
SUPFAMiSSF52080 SSF52080, 1 hit
PROSITEiView protein in PROSITE
PS00475 RIBOSOMAL_L15, 1 hit

Sequencei

Sequence statusi: Complete.

P41092-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNIKRKKTR KLRGHVSHGH GRIGKHRKHP GGRGNAGGMH HHRINFDKYH
60 70 80 90 100
PGYFGKVGMR NFHLRRQHKF RPEINLDKLW SLVGAEKFAE LEKEKSTKAP
110 120 130 140
VIDLVKFGYY KLLGRGHLPA RPVIVKAKYF SKKAEDKIKK AGGVCLLSA
Length:149
Mass (Da):17,022
Last modified:May 2, 2002 - v2
Checksum:i7777397307B89DCC
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti2S → R in CAA52601 (PubMed:8297386).Curated1
Sequence conflicti36A → L in CAA52601 (PubMed:8297386).Curated1
Sequence conflicti140K → E in CAA52601 (PubMed:8297386).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X74484 mRNA Translation: CAA52601.1
U66357 Genomic DNA Translation: AAC47475.1
U66358 mRNA Translation: AAC47472.1
AE014134 Genomic DNA Translation: AAF51006.3
AY071144 mRNA Translation: AAL48766.1
PIRiJC2392
JC6202
RefSeqiNP_001188689.2, NM_001201760.2
NP_001285601.1, NM_001298672.1
NP_476963.1, NM_057615.6
UniGeneiDm.295

Genome annotation databases

EnsemblMetazoaiFBtr0077452; FBpp0077142; FBgn0285948
FBtr0335136; FBpp0307135; FBgn0285948
FBtr0345285; FBpp0311452; FBgn0285948
GeneIDi33654
KEGGidme:Dmel_CG15442

Similar proteinsi

Entry informationi

Entry nameiRL27A_DROME
AccessioniPrimary (citable) accession number: P41092
Secondary accession number(s): Q94530, Q9VR02
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: May 2, 2002
Last modified: July 18, 2018
This is version 142 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
  4. SIMILARITY comments
    Index of protein domains and families

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