UniProtKB - P40987 (CIN1_YEAST)
Protein
Chromosome instability protein 1
Gene
CIN1
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
Required for microtubule stability. Interacts with CIN4.
Miscellaneous
Present with 704 molecules/cell in log phase SD medium.1 Publication
GO - Molecular functioni
- beta-tubulin binding Source: SGD
- GTPase activator activity Source: GO_Central
GO - Biological processi
- microtubule cytoskeleton organization Source: GO_Central
- post-chaperonin tubulin folding pathway Source: InterPro
- protein folding Source: SGD
- tubulin complex assembly Source: SGD
Names & Taxonomyi
Protein namesi | Recommended name: Chromosome instability protein 1 |
Gene namesi | Name:CIN1 Ordered Locus Names:YOR349W ORF Names:O6350 |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
EuPathDBi | FungiDB:YOR349W |
SGDi | S000005876, CIN1 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000089761 | 1 – 1014 | Chromosome instability protein 1Add BLAST | 1014 |
Proteomic databases
MaxQBi | P40987 |
PaxDbi | P40987 |
PRIDEi | P40987 |
PTM databases
iPTMneti | P40987 |
Interactioni
GO - Molecular functioni
- beta-tubulin binding Source: SGD
Protein-protein interaction databases
BioGRIDi | 34734, 226 interactors |
DIPi | DIP-5809N |
IntActi | P40987, 2 interactors |
MINTi | P40987 |
STRINGi | 4932.YOR349W |
Miscellaneous databases
RNActi | P40987, protein |
Family & Domainsi
Phylogenomic databases
eggNOGi | KOG1943, Eukaryota |
HOGENOMi | CLU_288698_0_0_1 |
InParanoidi | P40987 |
OMAi | GVFAKFY |
Family and domain databases
InterProi | View protein in InterPro IPR033162, TBCD |
PANTHERi | PTHR12658, PTHR12658, 1 hit |
i Sequence
Sequence statusi: Complete.
P40987-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNNIRALLDS IQSGVQTVSP EKHQQTIAAI NKFQDDPALL DTILPRCVPL
60 70 80 90 100
LTKSFFCMSQ RDQKLVAELF YNLDKISHSK VLKSLDTSIF RLNEILNYLQ
110 120 130 140 150
DRASPSSFSD VLCVYLNLSW LSVILLSPYA FKDKFNKTLQ VSSRFENYPI
160 170 180 190 200
CIPPINKIKA VLYFKNFTDA FDQLPEREQA NVPFLNQFLK LFIQSSEKAN
210 220 230 240 250
YYFSNENLRH LQQVALSNDG IKLLPKLFQI SFNHGSHDIL DAIVEFFHDH
260 270 280 290 300
LSSNSTDTRF QLAHSFAKIA KFLHQADPAS FIELIDYTIE NTVSLLQAPC
310 320 330 340 350
DSIDSNELHT SLLIIAEVAL AKILPIDLVD RVLTLIIPKT CHFQKSHFQI
360 370 380 390 400
IKGHHIRDST NFIIWSVIRS NRSNSLSPQV LQSLLSHLLI NAFFDPELII
410 420 430 440 450
RYSSFAALQE LLGRSNKSLA LNQNDIALIL QANWKDLPRS FEENSGLIRR
460 470 480 490 500
LFNPENTSKS AVCVWKVFRD WSFNWNLLEN LHLTTMKLNI DYNLVPLIKS
510 520 530 540 550
KLSSPALLQE VLNKAGSSVT QNCQILYLYL KLFENDVNCP KISEICIDIY
560 570 580 590 600
QKKIKFQLTT QAKRQFNDNS PELFQIFVIL KYWQLTGQND FNQELFWKFV
610 620 630 640 650
DIVSPQKKLN LYNEFIPIIQ QIISQCVSLN YTRIVQLIKS DNELTCRSIC
660 670 680 690 700
HMPDQEKMCS LFFSQFPLLS PQSRSLLIGE LDHHWDVRIS LLPSNSYRKF
710 720 730 740 750
RNIIINCLDD YTITQQGDVG RLVRIQALKL MQSHPDFLSG DCDSINPKLT
760 770 780 790 800
RLLAEPVPEI RKLSYQLLAS ATSQITVLSD SSILNFRHKQ GLSEEFWKGY
810 820 830 840 850
AVSAGAIHFT DSQLTSSIDS FIVYYRSLSP SQQLELCHDL IRIIPSAKQI
860 870 880 890 900
AESRIRDRNK DPLTGGMRFD TIKFTIHCVK FWTRIMESGL VVLHPNFNFQ
910 920 930 940 950
GVFAKFYNLH LLDCTTLRVS VIKFFPFLAI SCYHTMRENA DQKNLSNIIL
960 970 980 990 1000
KRLLVLVKRE YAATKSKFMT DQNVALQGMF QIFLELGVTR QLQALQVACQ
1010
KHELANILES DITL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z46420 Genomic DNA Translation: CAA86556.1 X95720 Genomic DNA Translation: CAA65036.1 Z75257 Genomic DNA Translation: CAA99677.1 Z75258 Genomic DNA Translation: CAA99679.1 BK006948 Genomic DNA Translation: DAA11110.1 |
PIRi | S48235 |
RefSeqi | NP_014994.3, NM_001183769.3 |
Genome annotation databases
EnsemblFungii | YOR349W_mRNA; YOR349W; YOR349W |
GeneIDi | 854531 |
KEGGi | sce:YOR349W |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z46420 Genomic DNA Translation: CAA86556.1 X95720 Genomic DNA Translation: CAA65036.1 Z75257 Genomic DNA Translation: CAA99677.1 Z75258 Genomic DNA Translation: CAA99679.1 BK006948 Genomic DNA Translation: DAA11110.1 |
PIRi | S48235 |
RefSeqi | NP_014994.3, NM_001183769.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 34734, 226 interactors |
DIPi | DIP-5809N |
IntActi | P40987, 2 interactors |
MINTi | P40987 |
STRINGi | 4932.YOR349W |
PTM databases
iPTMneti | P40987 |
Proteomic databases
MaxQBi | P40987 |
PaxDbi | P40987 |
PRIDEi | P40987 |
Genome annotation databases
EnsemblFungii | YOR349W_mRNA; YOR349W; YOR349W |
GeneIDi | 854531 |
KEGGi | sce:YOR349W |
Organism-specific databases
EuPathDBi | FungiDB:YOR349W |
SGDi | S000005876, CIN1 |
Phylogenomic databases
eggNOGi | KOG1943, Eukaryota |
HOGENOMi | CLU_288698_0_0_1 |
InParanoidi | P40987 |
OMAi | GVFAKFY |
Miscellaneous databases
PROi | PR:P40987 |
RNActi | P40987, protein |
Family and domain databases
InterProi | View protein in InterPro IPR033162, TBCD |
PANTHERi | PTHR12658, PTHR12658, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | CIN1_YEAST | |
Accessioni | P40987Primary (citable) accession number: P40987 Secondary accession number(s): D6W344 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1995 |
Last sequence update: | February 1, 1995 | |
Last modified: | December 2, 2020 | |
This is version 156 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Yeast chromosome XV
Yeast (Saccharomyces cerevisiae) chromosome XV: entries and gene names - Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD