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UniProtKB - P40901 (ISP5_SCHPO)
Protein
Sexual differentiation process putative amino-acid permease isp5
Gene
isp5
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Functioni
GO - Molecular functioni
- amino acid transmembrane transporter activity Source: PomBase
GO - Biological processi
- amino acid transmembrane transport Source: PomBase
Keywordsi
Biological process | Amino-acid transport, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Sexual differentiation process putative amino-acid permease isp5 |
Gene namesi | Name:isp5 ORF Names:SPAC1039.09 |
Organismi | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
Taxonomic identifieri | 284812 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › |
Proteomesi |
|
Organism-specific databases
PomBasei | SPAC1039.09, isp5 |
VEuPathDBi | FungiDB:SPAC1039.09 |
Subcellular locationi
Other locations
- Membrane Curated; Multi-pass membrane protein Curated
Endoplasmic reticulum
- endoplasmic reticulum Source: PomBase
Other locations
- integral component of membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 112 – 132 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 189 – 209 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 222 – 242 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 310 – 330 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 408 – 428 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 432 – 452 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 488 – 508 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 515 – 535 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000054167 | 1 – 580 | Sexual differentiation process putative amino-acid permease isp5Add BLAST | 580 |
Proteomic databases
MaxQBi | P40901 |
PaxDbi | P40901 |
Expressioni
Developmental stagei
Transcribed specifically during sexual development.
Interactioni
Protein-protein interaction databases
BioGRIDi | 279464, 1 interactor |
STRINGi | 4896.SPAC1039.09.1 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 30 | DisorderedSequence analysisAdd BLAST | 30 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 23 | Polar residuesSequence analysisAdd BLAST | 23 |
Sequence similaritiesi
Belongs to the amino acid-polyamine-organocation (APC) superfamily.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG1286, Eukaryota |
HOGENOMi | CLU_007946_12_0_1 |
InParanoidi | P40901 |
OMAi | HGFHGFC |
PhylomeDBi | P40901 |
Family and domain databases
InterProi | View protein in InterPro IPR004841, AA-permease/SLC12A_dom IPR004840, Amoino_acid_permease_CS |
Pfami | View protein in Pfam PF00324, AA_permease, 1 hit |
PROSITEi | View protein in PROSITE PS00218, AMINO_ACID_PERMEASE_1, 1 hit |
i Sequence
Sequence statusi: Complete.
P40901-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNNYGVSSIG TSLTPSPTGS IDEYTSKEVK HPEDVKVDAS YEKEEVGYGE
60 70 80 90 100
LEVVPERGNL FQRWYRSFLP PEDGKPQKLK RTLTARHIQM IGIGGAIGTG
110 120 130 140 150
VWVGSKNTLR EGGAASVLIC YSLVGSMVLM TVYSLGELAV AFPINGSFHT
160 170 180 190 200
YGTRFIHPSW GFTLGWNYLA SFLATYPLEL ITASICLQFW ININSGIWIT
210 220 230 240 250
VFIALLCFVN MFGVRGYGEV EFFVSSLKVM AMVGFIICGI VIDCGGVRTD
260 270 280 290 300
HRGYIGATIF RKNAFIHGFH GFCSVFSTAA FSYAGTEYIG IAASETKNPA
310 320 330 340 350
KAFPKAVKQV FIRVSLFYIL ALFVVSLLIS GRDERLTTLS ATAASPFILA
360 370 380 390 400
LMDAKIRGLP HVLNAVILIS VLTAANGITY TGSRTLHSMA EQGHAPKWFK
410 420 430 440 450
YVDREGRPLL AMAFVLCFGA LGYICESAQS DTVFDWLLSI SNLATLFVWL
460 470 480 490 500
SINVSYIIYR LAFKKQGKSY DEVGYHSPFG IYGACYGAFI IILVFITEFY
510 520 530 540 550
VSIFPIGASP DAGAFFQSYL CFPVVVIVFI AHALITRQKF RKLSEIDLDT
560 570 580
GFSKYDRLEE SDKGPMTAKS LAKSVLSFCV
Sequence cautioni
The sequence BAA03148 differs from that shown. Reason: Frameshift.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D14062 mRNA Translation: BAA03148.1 Frameshift. CU329670 Genomic DNA Translation: CAB63545.1 |
PIRi | S45492 T50059 |
RefSeqi | NP_595000.1, NM_001020431.2 |
Genome annotation databases
EnsemblFungii | SPAC1039.09.1; SPAC1039.09.1:pep; SPAC1039.09 |
GeneIDi | 2543028 |
KEGGi | spo:SPAC1039.09 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D14062 mRNA Translation: BAA03148.1 Frameshift. CU329670 Genomic DNA Translation: CAB63545.1 |
PIRi | S45492 T50059 |
RefSeqi | NP_595000.1, NM_001020431.2 |
3D structure databases
SMRi | P40901 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 279464, 1 interactor |
STRINGi | 4896.SPAC1039.09.1 |
Proteomic databases
MaxQBi | P40901 |
PaxDbi | P40901 |
Genome annotation databases
EnsemblFungii | SPAC1039.09.1; SPAC1039.09.1:pep; SPAC1039.09 |
GeneIDi | 2543028 |
KEGGi | spo:SPAC1039.09 |
Organism-specific databases
PomBasei | SPAC1039.09, isp5 |
VEuPathDBi | FungiDB:SPAC1039.09 |
Phylogenomic databases
eggNOGi | KOG1286, Eukaryota |
HOGENOMi | CLU_007946_12_0_1 |
InParanoidi | P40901 |
OMAi | HGFHGFC |
PhylomeDBi | P40901 |
Miscellaneous databases
PROi | PR:P40901 |
Family and domain databases
InterProi | View protein in InterPro IPR004841, AA-permease/SLC12A_dom IPR004840, Amoino_acid_permease_CS |
Pfami | View protein in Pfam PF00324, AA_permease, 1 hit |
PROSITEi | View protein in PROSITE PS00218, AMINO_ACID_PERMEASE_1, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | ISP5_SCHPO | |
Accessioni | P40901Primary (citable) accession number: P40901 Secondary accession number(s): Q9US32 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1995 |
Last sequence update: | August 14, 2001 | |
Last modified: | February 23, 2022 | |
This is version 147 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Schizosaccharomyces pombe
Schizosaccharomyces pombe: entries and gene names - SIMILARITY comments
Index of protein domains and families