Transcription factor SOX-6

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• DNA binding Source: MGI <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayⁱ
  • "Mouse mu opioid receptor distal promoter transcriptional regulation by SOX proteins."
    Hwang C.K., Wu X., Wang G., Kim C.S., Loh H.H.
    J. Biol. Chem. 278:3742-3750(2003) [PubMed] [Europe PMC] [Abstract]
• DNA-binding transcription factor activity Source: MGIInferred from direct assayⁱ
  • "Mouse mu opioid receptor distal promoter transcriptional regulation by SOX proteins."
    Hwang C.K., Wu X., Wang G., Kim C.S., Loh H.H.
    J. Biol. Chem. 278:3742-3750(2003) [PubMed] [Europe PMC] [Abstract]
  • "SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function."
    Stolt C.C., Schlierf A., Lommes P., Hillgartner S., Werner T., Kosian T., Sock E., Kessaris N., Richardson W.D., Lefebvre V., Wegner M.
    Dev. Cell 11:697-709(2006) [PubMed] [Europe PMC] [Abstract]
• DNA-binding transcription repressor activity, RNA polymerase II-specific Source: NTNU_SB <p>Inferred from Mutant Phenotype</p> <p>Describes annotations that are concluded from looking at variations or changes in a gene product such as mutations or abnormal levels and includes techniques such as knockouts, overexpression, anti-sense experiments and use of specific protein inhibitors.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#imp">GO evidence code guide</a></p> Inferred from mutant phenotypeⁱ
  • "Sox6 directly silences epsilon globin expression in definitive erythropoiesis."
    Yi Z., Cohen-Barak O., Hagiwara N., Kingsley P.D., Fuchs D.A., Erickson D.T., Epner E.M., Palis J., Brilliant M.H.
    PLoS Genet. 2:e14-e14(2006) [PubMed] [Europe PMC] [Abstract]
• RNA polymerase II proximal promoter sequence-specific DNA binding Source: NTNU_SBInferred from mutant phenotypeⁱ
  • "Sox6 directly silences epsilon globin expression in definitive erythropoiesis."
    Yi Z., Cohen-Barak O., Hagiwara N., Kingsley P.D., Fuchs D.A., Erickson D.T., Epner E.M., Palis J., Brilliant M.H.
    PLoS Genet. 2:e14-e14(2006) [PubMed] [Europe PMC] [Abstract]
• protein heterodimerization activity Source: MGI <p>Inferred from Physical Interaction</p> <p>Covers physical interactions between the gene product of interest and another molecule (or ion, or complex).</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ipi">GO evidence code guide</a></p> Inferred from physical interactionⁱ
  • Ref.3

    "A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene."
    Lefebvre V., Li P., de Crombrugghe B.
    EMBO J. 17:5718-5733(1998) [PubMed] [Europe PMC] [Abstract]

    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 519-827.
• sequence-specific DNA binding Source: MGIInferred from direct assayⁱ
  • "Sox6 directly silences epsilon globin expression in definitive erythropoiesis."
    Yi Z., Cohen-Barak O., Hagiwara N., Kingsley P.D., Fuchs D.A., Erickson D.T., Epner E.M., Palis J., Brilliant M.H.
    PLoS Genet. 2:e14-e14(2006) [PubMed] [Europe PMC] [Abstract]
• transcription regulatory region DNA binding Source: MGIInferred from direct assayⁱ
  • "SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function."
    Stolt C.C., Schlierf A., Lommes P., Hillgartner S., Werner T., Kosian T., Sock E., Kessaris N., Richardson W.D., Lefebvre V., Wegner M.
    Dev. Cell 11:697-709(2006) [PubMed] [Europe PMC] [Abstract]

GO - Biological processⁱ

• astrocyte differentiation Source: MGI
• cardiac muscle cell differentiation Source: MGIInferred from direct assayⁱ
  • Ref.7

    "Sox6 regulation of cardiac myocyte development."
    Cohen-Barak O., Yi Z., Hagiwara N., Monzen K., Komuro I., Brilliant M.H.
    Nucleic Acids Res. 31:5941-5948(2003) [PubMed] [Europe PMC] [Abstract]

    Cited for: INTERACTION WITH DAZAP2.
• cartilage development Source: MGI <p>Inferred from Genetic Interaction</p> <p>Used to describe “traditional” genetic interactions such as suppressors and synthetic lethals as well as other techniques such as functional complementation, rescue experiments, or inferences about a gene drawn from the phenotype of a mutation in a different gene.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#igi">GO evidence code guide</a></p> Inferred from genetic interactionⁱ
  • "Genetic analysis of interactions between the somitic muscle, cartilage and tendon cell lineages during mouse development."
    Brent A.E., Braun T., Tabin C.J.
    Development 132:515-528(2005) [PubMed] [Europe PMC] [Abstract]
• cell fate commitment Source: MGIInferred from genetic interactionⁱ
  • "Genetic analysis of interactions between the somitic muscle, cartilage and tendon cell lineages during mouse development."
    Brent A.E., Braun T., Tabin C.J.
    Development 132:515-528(2005) [PubMed] [Europe PMC] [Abstract]
• cell morphogenesis Source: MGIInferred from mutant phenotypeⁱ
  • "Sox6 directly silences epsilon globin expression in definitive erythropoiesis."
    Yi Z., Cohen-Barak O., Hagiwara N., Kingsley P.D., Fuchs D.A., Erickson D.T., Epner E.M., Palis J., Brilliant M.H.
    PLoS Genet. 2:e14-e14(2006) [PubMed] [Europe PMC] [Abstract]
• cellular response to transforming growth factor beta stimulus Source: MGI
• erythrocyte development Source: MGIInferred from mutant phenotypeⁱ
  • "Sox6 directly silences epsilon globin expression in definitive erythropoiesis."
    Yi Z., Cohen-Barak O., Hagiwara N., Kingsley P.D., Fuchs D.A., Erickson D.T., Epner E.M., Palis J., Brilliant M.H.
    PLoS Genet. 2:e14-e14(2006) [PubMed] [Europe PMC] [Abstract]
• erythrocyte differentiation Source: MGIInferred from mutant phenotypeⁱ
  • "Sox6 is necessary for efficient erythropoiesis in adult mice under physiological and anemia-induced stress conditions."
    Dumitriu B., Bhattaram P., Dy P., Huang Y., Quayum N., Jensen J., Lefebvre V.
    PLoS ONE 5:e12088-e12088(2010) [PubMed] [Europe PMC] [Abstract]
• gene silencing Source: MGIInferred from mutant phenotypeⁱ
  • "Sox6 directly silences epsilon globin expression in definitive erythropoiesis."
    Yi Z., Cohen-Barak O., Hagiwara N., Kingsley P.D., Fuchs D.A., Erickson D.T., Epner E.M., Palis J., Brilliant M.H.
    PLoS Genet. 2:e14-e14(2006) [PubMed] [Europe PMC] [Abstract]
• hemopoiesis Source: MGIInferred from mutant phenotypeⁱ
  • "Sox6 directly silences epsilon globin expression in definitive erythropoiesis."
    Yi Z., Cohen-Barak O., Hagiwara N., Kingsley P.D., Fuchs D.A., Erickson D.T., Epner E.M., Palis J., Brilliant M.H.
    PLoS Genet. 2:e14-e14(2006) [PubMed] [Europe PMC] [Abstract]
• in utero embryonic development Source: MGIInferred from mutant phenotypeⁱ
  • "SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function."
    Stolt C.C., Schlierf A., Lommes P., Hillgartner S., Werner T., Kosian T., Sock E., Kessaris N., Richardson W.D., Lefebvre V., Wegner M.
    Dev. Cell 11:697-709(2006) [PubMed] [Europe PMC] [Abstract]
• muscle cell differentiation Source: MGIInferred from direct assayⁱ
  • Ref.7

    "Sox6 regulation of cardiac myocyte development."
    Cohen-Barak O., Yi Z., Hagiwara N., Monzen K., Komuro I., Brilliant M.H.
    Nucleic Acids Res. 31:5941-5948(2003) [PubMed] [Europe PMC] [Abstract]

    Cited for: INTERACTION WITH DAZAP2.
• negative regulation of cardiac muscle cell differentiation Source: MGI
• negative regulation of transcription by RNA polymerase II Source: MGIInferred from direct assayⁱ
  • "Sox6 directly silences epsilon globin expression in definitive erythropoiesis."
    Yi Z., Cohen-Barak O., Hagiwara N., Kingsley P.D., Fuchs D.A., Erickson D.T., Epner E.M., Palis J., Brilliant M.H.
    PLoS Genet. 2:e14-e14(2006) [PubMed] [Europe PMC] [Abstract]
• negative regulation of transcription, DNA-templated Source: MGIInferred from direct assayⁱ
  • "SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function."
    Stolt C.C., Schlierf A., Lommes P., Hillgartner S., Werner T., Kosian T., Sock E., Kessaris N., Richardson W.D., Lefebvre V., Wegner M.
    Dev. Cell 11:697-709(2006) [PubMed] [Europe PMC] [Abstract]
• oligodendrocyte cell fate specification Source: MGIInferred from mutant phenotypeⁱ
  • "SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function."
    Stolt C.C., Schlierf A., Lommes P., Hillgartner S., Werner T., Kosian T., Sock E., Kessaris N., Richardson W.D., Lefebvre V., Wegner M.
    Dev. Cell 11:697-709(2006) [PubMed] [Europe PMC] [Abstract]
• oligodendrocyte differentiation Source: MGIInferred from mutant phenotypeⁱ
  • "SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function."
    Stolt C.C., Schlierf A., Lommes P., Hillgartner S., Werner T., Kosian T., Sock E., Kessaris N., Richardson W.D., Lefebvre V., Wegner M.
    Dev. Cell 11:697-709(2006) [PubMed] [Europe PMC] [Abstract]
• positive regulation of cartilage development Source: MGI
• positive regulation of chondrocyte differentiation Source: UniProtKBInferred from direct assayⁱ
  • "The transcription factor Znf219 regulates chondrocyte differentiation by assembling a transcription factory with Sox9."
    Takigawa Y., Hata K., Muramatsu S., Amano K., Ono K., Wakabayashi M., Matsuda A., Takada K., Nishimura R., Yoneda T.
    J. Cell Sci. 123:3780-3788(2010) [PubMed] [Europe PMC] [Abstract]
• positive regulation of mesenchymal stem cell differentiation Source: MGI
• positive regulation of transcription by RNA polymerase II Source: MGIInferred from genetic interactionⁱ
  • Ref.3

    "A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene."
    Lefebvre V., Li P., de Crombrugghe B.
    EMBO J. 17:5718-5733(1998) [PubMed] [Europe PMC] [Abstract]

    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 519-827.
• positive regulation of transcription, DNA-templated Source: MGIInferred from direct assayⁱ
  • "SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function."
    Stolt C.C., Schlierf A., Lommes P., Hillgartner S., Werner T., Kosian T., Sock E., Kessaris N., Richardson W.D., Lefebvre V., Wegner M.
    Dev. Cell 11:697-709(2006) [PubMed] [Europe PMC] [Abstract]
• post-embryonic development Source: MGIInferred from mutant phenotypeⁱ
  • "Sox6 directly silences epsilon globin expression in definitive erythropoiesis."
    Yi Z., Cohen-Barak O., Hagiwara N., Kingsley P.D., Fuchs D.A., Erickson D.T., Epner E.M., Palis J., Brilliant M.H.
    PLoS Genet. 2:e14-e14(2006) [PubMed] [Europe PMC] [Abstract]
• regulation of gene expression Source: MGIInferred from mutant phenotypeⁱ
  • "Sox6 is necessary for efficient erythropoiesis in adult mice under physiological and anemia-induced stress conditions."
    Dumitriu B., Bhattaram P., Dy P., Huang Y., Quayum N., Jensen J., Lefebvre V.
    PLoS ONE 5:e12088-e12088(2010) [PubMed] [Europe PMC] [Abstract]
• regulation of transcription, DNA-templated Source: MGIInferred from direct assayⁱ
  • "Mouse mu opioid receptor distal promoter transcriptional regulation by SOX proteins."
    Hwang C.K., Wu X., Wang G., Kim C.S., Loh H.H.
    J. Biol. Chem. 278:3742-3750(2003) [PubMed] [Europe PMC] [Abstract]

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsⁱ

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

Keywords - Cellular componentⁱ

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingⁱ

Molecule processing

Amino acid modifications

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationⁱ

Keywords - PTMⁱ

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressionⁱ

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityⁱ

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structureⁱ

GO - Molecular functionⁱ

• protein heterodimerization activity Source: MGIInferred from physical interactionⁱ
  • Ref.3

    "A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene."
    Lefebvre V., Li P., de Crombrugghe B.
    EMBO J. 17:5718-5733(1998) [PubMed] [Europe PMC] [Abstract]

    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 519-827.

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structureⁱ

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Coiled coil

Compositional bias

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)ⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

This entry has 2 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All

        10         20         30         40         50
MSSKQATSPF ACTADGEEAM TQDLTSREKE EGSDQHPASH LPLHPIMHNK 
        60         70         80         90        100
PHSEELPTLV STIQQDADWD SVLSSQQRME SENNKLCSLY SFRNTSTSPH 
       110        120        130        140        150
KPDEGSRERE IMNSVTFGTP ERRKGSLADV VDTLKQKKLE EMTRTEQEDS 
       160        170        180        190        200
SCMEKLLSKD WKEKMERLNT SELLGEIKGT PESLAEKERQ LSTMITQLIS 
       210        220        230        240        250
LREQLLAAHD EQKKLAASQI EKQRQQMDLA RQQQEQIARQ QQQLLQQQHK 
       260        270        280        290        300
INLLQQQIQV QGHMPPLMIP IFPHDQRTLA AAAAAQQGFL FPPGITYKPG 
       310        320        330        340        350
DNYPVQFIPS TMAAAAASGL SPLQLQKGHV SHPQINPRLK GISDRFGRNL 
       360        370        380        390        400
DPSEHGGGHS YNHRQIEQLY AAQLASMQVS PGAKMPSTPQ PPNSAGAVSP 
       410        420        430        440        450
TGIKNEKRGT SPVTQVKDET TAQPLNLSSR PKTAEPVKSP TSPTQNLFPA 
       460        470        480        490        500
SKTSPVNLPN KSSIPSPIGG SLGRGSSLDI LSSLNSPALF GDQDTVMKAI 
       510        520        530        540        550
QEARKMREQI QREQQQQPHG VDGKLSSMNN MGLSNCRTEK ERTRFENLGP 
       560        570        580        590        600
QLTGKSSEDG KLGPGVIDLT RPEDAEGSKA MNGSAAKLQQ YYCWPTGGAT 
       610        620        630        640        650
VAEARVYRDA RGRASSEPHI KRPMNAFMVW AKDERRKILQ AFPDMHNSNI 
       660        670        680        690        700
SKILGSRWKS MSNQEKQPYY EEQARLSKIH LEKYPNYKYK PRPKRTCIVD 
       710        720        730        740        750
GKKLRIGEYK QLMRSRRQEM RQFFTVGQQP QMPITTGTGV VYPGAITMAT 
       760        770        780        790        800
TTPSPQMTSD CSSTSASPEP SLPVIQSTYG MKMDGASLAG NDMINGEDEM 
       810        820 
EAYDDYEDDP KSDYSSENEA PEPVSAN                          

        10         20         30         40         50
MSSKQATSPF ACTADGEEAM TQDLTSREKE EGSDQHPASH LPLHPIMHNK 
        60         70         80         90        100
PHSEELPTLV STIQQDADWD SVLSSQQRME SENNKLCSLY SFRNTSTSPH 
       110        120        130        140        150
KPDEGSRERE IMNSVTFGTP ERRKGSLADV VDTLKQKKLE EMTRTEQEDS 
       160        170        180        190        200
SCMEKLLSKD WKEKMERLNT SELLGEIKGT PESLAEKERQ LSTMITQLIS 
       210        220        230        240        250
LREQLLAAHD EQKKLAASQI EKQRQQMDLA RQQQEQIARQ QQQLLQQQHK 
       260        270        280        290        300
INLLQQQIQV QGHMPPLMIP IFPHDQRTLA AAAAAQQGFL FPPGITYKPG 
       310        320        330        340        350
DNYPVQFIPS TMAAAAASGL SPLQLQQLYA AQLASMQVSP GAKMPSTPQP 
       360        370        380        390        400
PNSAGAVSPT GIKNEKRGTS PVTQVKDETT AQPLNLSSRP KTAEPVKSPT 
       410        420        430        440        450
SPTQNLFPAS KTSPVNLPNK SSIPSPIGGS LGRGSSLDIL SSLNSPALFG 
       460        470        480        490        500
DQDTVMKAIQ EARKMREQIQ REQQQQPHGV DGKLSSMNNM GLSNCRTEKE 
       510        520        530        540        550
RTRFENLGPQ LTGKSSEDGK LGPGVIDLTR PEDAEGSKAM NGSAAKLQQY 
       560        570        580        590        600
YCWPTGGATV AEARVYRDAR GRASSEPHIK RPMNAFMVWA KDERRKILQA 
       610        620        630        640        650
FPDMHNSNIS KILGSRWKSM SNQEKQPYYE EQARLSKIHL EKYPNYKYKP 
       660        670        680        690        700
RPKRTCIVDG KKLRIGEYKQ LMRSRRQEMR QFFTVGQQPQ MPITTGTGVV 
       710        720        730        740        750
YPGAITMATT TPSPQMTSDC SSTSASPEPS LPVIQSTYGM KMDGASLAGN 
       760        770        780 
DMINGEDEME AYDDYEDDPK SDYSSENEAP EPVSAN                

Experimental Info

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityⁱ

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 100% Identity
• 90% Identity
• 50% Identity

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

Keywords - Technical termⁱ

Documents

1. MGD cross-references
   Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot