UniProtKB - P40578 (MGA2_YEAST)
Protein
Protein MGA2
Gene
MGA2
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
Miscellaneous
Present with 300 molecules/cell in log phase SD medium.1 Publication
GO - Biological processi
- cellular response to cold Source: SGD
- mRNA stabilization Source: SGD
- positive regulation of transcription by RNA polymerase II Source: SGD
- positive regulation of transcription from RNA polymerase II promoter in response to cobalt ion Source: SGD
- positive regulation of transcription from RNA polymerase II promoter in response to hypoxia Source: SGD
- positive regulation of transcription from RNA polymerase II promoter in response to iron ion starvation Source: SGD
- silent mating-type cassette heterochromatin assembly Source: SGD
Names & Taxonomyi
Protein namesi | Recommended name: Protein MGA2 |
Gene namesi | Name:MGA2 Ordered Locus Names:YIR033W |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
EuPathDBi | FungiDB:YIR033W |
SGDi | S000001472, MGA2 |
Subcellular locationi
Other locations
- Membrane Curated; Single-pass membrane protein Curated
Endoplasmic reticulum
- endoplasmic reticulum Source: SGD
- integral component of endoplasmic reticulum membrane Source: SGD
Nucleus
- nucleus Source: SGD
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 1037 – 1054 | HelicalSequence analysisAdd BLAST | 18 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000067074 | 1 – 1113 | Protein MGA2Add BLAST | 1113 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 255 | PhosphoserineCombined sources | 1 | |
Modified residuei | 467 | PhosphoserineCombined sources | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
MaxQBi | P40578 |
PaxDbi | P40578 |
PRIDEi | P40578 |
PTM databases
iPTMneti | P40578 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 35024, 513 interactors |
DIPi | DIP-6689N |
IntActi | P40578, 21 interactors |
MINTi | P40578 |
STRINGi | 4932.YIR033W |
Miscellaneous databases
RNActi | P40578, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 530 – 610 | IPT/TIGAdd BLAST | 81 | |
Repeati | 719 – 748 | ANK 1Add BLAST | 30 | |
Repeati | 752 – 781 | ANK 2Add BLAST | 30 |
Keywords - Domaini
ANK repeat, Repeat, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG3836, Eukaryota |
HOGENOMi | CLU_004311_0_0_1 |
InParanoidi | P40578 |
OMAi | LIFFWIP |
Family and domain databases
Gene3Di | 1.25.40.20, 1 hit 2.60.40.10, 1 hit |
InterProi | View protein in InterPro IPR002110, Ankyrin_rpt IPR020683, Ankyrin_rpt-contain_dom IPR036770, Ankyrin_rpt-contain_sf IPR013783, Ig-like_fold IPR014756, Ig_E-set IPR002909, IPT_dom |
Pfami | View protein in Pfam PF12796, Ank_2, 1 hit PF01833, TIG, 1 hit |
SMARTi | View protein in SMART SM00248, ANK, 2 hits SM00429, IPT, 1 hit |
SUPFAMi | SSF48403, SSF48403, 1 hit SSF81296, SSF81296, 1 hit |
PROSITEi | View protein in PROSITE PS50297, ANK_REP_REGION, 1 hit PS50088, ANK_REPEAT, 2 hits |
i Sequence
Sequence statusi: Complete.
P40578-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MQQNSEFLTE TPGSDPHISQ LHANSVMESQ LLDDFLLNGS PMYQDDSMAH
60 70 80 90 100
INIDEGANFQ NFIKTDEGDS PNLLSFEGIG NNTHVNQNVS TPLEEEMESN
110 120 130 140 150
RALKEEEEDE HENKVFNEKN IGNPAHDEIV FGRKETIQSV YINPLDYLKV
160 170 180 190 200
NAAQLPLDVE VSGLPQVSRV ENQLKLKVKI TSETPLNQSM LYLPSDSISR
210 220 230 240 250
EKFYLKKNIE DFSEDFKKNL LYINAFVLCA VSNRTTNVCT KCVKREQRRA
260 270 280 290 300
ARRKSGIADN LLWCNNINRR LVVFNNKQVF PIMKTFDNVK EFELTTRLVC
310 320 330 340 350
YCRHHKANNG FVILFTITDW QNRLLGKFTT TPIMITDRKP ANMDTTKFNN
360 370 380 390 400
TTTSSRRQLT EEESTTEYYS TDNNQLSKDE NMPFQYTYQH NPYDNDSQMN
410 420 430 440 450
NIPLKDKNVP FPYSISQQTD LLQNNNLSLN LSLPNQHIPS PTSMSEEGSE
460 470 480 490 500
SFNYHHRDND NPVRTISLTN IEQQSQLNQR KRARNNLEND IGKPLFKHSF
510 520 530 540 550
SNSISATNTM NPALHSMQDF SMKNNNNNLP SINRVIPSQG PINGGIEVTL
560 570 580 590 600
LGCNFKDGLS VKFGSNLALS TQCWSETTIV TYLPPAAYAG QVFVSITDTN
610 620 630 640 650
NENNNDDLPQ EIEINDNKKA IFTYVDDTDR QLIELALQIV GLKMNGKLED
660 670 680 690 700
ARNIAKRIVG NDSPDSGTNG NSCSKSTGPS PNQHSMNLNT SVLYSDEVLI
710 720 730 740 750
QKVIKSLNIN SNISICDSLG RTLLHLACLK NYSSLVYTLI KKGARVNDID
760 770 780 790 800
SFGLTPLHFA CISGDPKIIK MLLNCKVNYS LRSHNGLTAR EVFIANHIHS
810 820 830 840 850
KEIDKKQDNR DNHKFVHNDT YISEVLSLFE EFQNGTKFTD SVETDSNYSI
860 870 880 890 900
SRKYSQSSFN SSLLDNESLN ENLFESQSMI NPTSMEIQHP TLQLFENSSY
910 920 930 940 950
SEYDQSDFEE DGDEDLFVTD EVEKPGVACR EEQSELLDIG SSANEPEEDN
960 970 980 990 1000
GSTSLWNRVL HRINDDLPKY EDLFPLSWGK DDKLKTTNQD SIVEQSASNI
1010 1020 1030 1040 1050
ENSENSEEED YEEEEEFLKK QFNRFFQNKQ NFRNDKMLIF FWIPLTLLLL
1060 1070 1080 1090 1100
TWFIMYKFGN QDSSINHISE LISEYLRIAL AKFLLGNERM KTAFRSKLSN
1110
LQTTRMLNDL IVS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z38061 Genomic DNA Translation: CAA86193.1 BK006942 Genomic DNA Translation: DAA08580.1 |
PIRi | S48495 |
RefSeqi | NP_012299.1, NM_001179555.1 |
Genome annotation databases
EnsemblFungii | YIR033W_mRNA; YIR033W; YIR033W |
GeneIDi | 854851 |
KEGGi | sce:YIR033W |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z38061 Genomic DNA Translation: CAA86193.1 BK006942 Genomic DNA Translation: DAA08580.1 |
PIRi | S48495 |
RefSeqi | NP_012299.1, NM_001179555.1 |
3D structure databases
SMRi | P40578 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 35024, 513 interactors |
DIPi | DIP-6689N |
IntActi | P40578, 21 interactors |
MINTi | P40578 |
STRINGi | 4932.YIR033W |
PTM databases
iPTMneti | P40578 |
Proteomic databases
MaxQBi | P40578 |
PaxDbi | P40578 |
PRIDEi | P40578 |
Genome annotation databases
EnsemblFungii | YIR033W_mRNA; YIR033W; YIR033W |
GeneIDi | 854851 |
KEGGi | sce:YIR033W |
Organism-specific databases
EuPathDBi | FungiDB:YIR033W |
SGDi | S000001472, MGA2 |
Phylogenomic databases
eggNOGi | KOG3836, Eukaryota |
HOGENOMi | CLU_004311_0_0_1 |
InParanoidi | P40578 |
OMAi | LIFFWIP |
Miscellaneous databases
PROi | PR:P40578 |
RNActi | P40578, protein |
Family and domain databases
Gene3Di | 1.25.40.20, 1 hit 2.60.40.10, 1 hit |
InterProi | View protein in InterPro IPR002110, Ankyrin_rpt IPR020683, Ankyrin_rpt-contain_dom IPR036770, Ankyrin_rpt-contain_sf IPR013783, Ig-like_fold IPR014756, Ig_E-set IPR002909, IPT_dom |
Pfami | View protein in Pfam PF12796, Ank_2, 1 hit PF01833, TIG, 1 hit |
SMARTi | View protein in SMART SM00248, ANK, 2 hits SM00429, IPT, 1 hit |
SUPFAMi | SSF48403, SSF48403, 1 hit SSF81296, SSF81296, 1 hit |
PROSITEi | View protein in PROSITE PS50297, ANK_REP_REGION, 1 hit PS50088, ANK_REPEAT, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | MGA2_YEAST | |
Accessioni | P40578Primary (citable) accession number: P40578 Secondary accession number(s): D6VVW4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1995 |
Last sequence update: | February 1, 1995 | |
Last modified: | December 2, 2020 | |
This is version 165 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD - Yeast chromosome IX
Yeast (Saccharomyces cerevisiae) chromosome IX: entries and gene names