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UniProtKB - P40429 (RL13A_HUMAN)

Protein

60S ribosomal protein L13a

Gene

RPL13A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex. Involved in methylation of rRNA.4 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • mRNA binding Source: GO_Central
  • RNA binding Source: UniProtKB
  • structural constituent of ribosome Source: GO_Central
View the complete GO annotation on QuickGO ...

GO - Biological processi

View the complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein
Biological processTranslation regulation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902 Peptide chain elongation
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823 Viral mRNA Translation
R-HSA-2408557 Selenocysteine synthesis
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72689 Formation of a pool of free 40S subunits
R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764 Eukaryotic Translation Termination
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

SIGNOR Signaling Network Open Resource

More...SIGNORi		P40429

Protein family/group databases

MoonProt database of moonlighting proteins

More...MoonProti		P40429

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
60S ribosomal protein L13a
Alternative name(s):
23 kDa highly basic protein
Large ribosomal subunit protein uL131 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RPL13A
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...EuPathDBi		HostDB:ENSG00000142541.16

Human Gene Nomenclature Database

More...HGNCi		HGNC:10304 RPL13A

neXtProt; the human protein knowledge platform

More...neXtProti		NX_P40429

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi77S → A: Loss of interferon-gamma induced phosphorylation. 1 Publication1

Organism-specific databases

DisGeNET

More...DisGeNETi		23521

Open Targets

More...OpenTargetsi		ENSG00000142541

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA38122

Chemistry databases

Drug and drug target database

More...DrugBanki		DB02494 Alpha-Hydroxy-Beta-Phenyl-Propionic Acid
DB07374 Anisomycin
DB08437 Puromycin

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		RPL13A

Domain mapping of disease mutations (DMDM)

More...DMDMi		730451

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedCombined sources3 Publications
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001337692 – 20360S ribosomal protein L13aAdd BLAST202

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylalanineCombined sources3 Publications1
Modified residuei59CitrullineBy similarity1
Modified residuei77Phosphoserine; by ZIPK/DAPK31 Publication1
Modified residuei140CitrullineBy similarity1
Modified residuei191N6-acetyllysineCombined sources1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylation at Ser-77 upon interferon-gamma treatment in monocytes involves a DAPK1-DAPK3 kinase cascade and is causing release from the ribosome, association with the GAIT complex and subsequent involvement in transcript-selective translation inhibition.2 Publications
Citrullinated by PADI4.By similarity

Keywords - PTMi

Acetylation, Citrullination, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		P40429

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		P40429

MaxQB - The MaxQuant DataBase

More...MaxQBi		P40429

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P40429

PeptideAtlas

More...PeptideAtlasi		P40429

PRoteomics IDEntifications database

More...PRIDEi		P40429

ProteomicsDB human proteome resource

More...ProteomicsDBi		55374

Consortium for Top Down Proteomics

More...TopDownProteomicsi		P40429

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P40429

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		P40429

SwissPalm database of S-palmitoylation events

More...SwissPalmi		P40429

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000142541 Expressed in 87 organ(s), highest expression level in left ovary

CleanEx database of gene expression profiles

More...CleanExi		HS_RPL13A

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		P40429 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		P40429 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		HPA038751

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the 60S ribosome. Component of the GAIT complex. Interacts with EIF4G1.1 Publication3 Publications

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		117068, 146 interactors

CORUM comprehensive resource of mammalian protein complexes

More...CORUMi		P40429

Protein interaction database and analysis system

More...IntActi		P40429, 55 interactors

Molecular INTeraction database

More...MINTi		P40429

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000375730

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4UG0electron microscopy-LO1-203[»]
4V6Xelectron microscopy5.00CO1-203[»]
5AJ0electron microscopy3.50AO1-203[»]
5LKSelectron microscopy3.60LO1-203[»]
5T2Celectron microscopy3.60I1-203[»]
6EK0electron microscopy2.90LO1-203[»]

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...ProteinModelPortali		P40429

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P40429

Database of comparative protein structure models

More...ModBasei		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the universal ribosomal protein uL13 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3204 Eukaryota
COG0102 LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00390000010799

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000225289

The HOVERGEN Database of Homologous Vertebrate Genes

More...HOVERGENi		HBG062176

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P40429

KEGG Orthology (KO)

More...KOi		K02872

Database of Orthologous Groups

More...OrthoDBi		1312756at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		P40429

TreeFam database of animal gene trees

More...TreeFami		TF300159

Family and domain databases

Conserved Domains Database

More...CDDi		cd00392 Ribosomal_L13, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.90.1180.10, 1 hit

HAMAP database of protein families

More...HAMAPi		MF_01366 Ribosomal_L13, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR005822 Ribosomal_L13
IPR023563 Ribosomal_L13_CS
IPR005755 Ribosomal_L13_euk/arc
IPR036899 Ribosomal_L13_sf

The PANTHER Classification System

More...PANTHERi		PTHR11545 PTHR11545, 1 hit
PTHR11545:SF3 PTHR11545:SF3, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00572 Ribosomal_L13, 1 hit

PIRSF; a whole-protein classification database

More...PIRSFi		PIRSF002181 Ribosomal_L13, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF52161 SSF52161, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR01077 L13_A_E, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00783 RIBOSOMAL_L13, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

P40429-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAEVQVLVLD GRGHLLGRLA AIVAKQVLLG RKVVVVRCEG INISGNFYRN 
        60         70         80         90        100
KLKYLAFLRK RMNTNPSRGP YHFRAPSRIF WRTVRGMLPH KTKRGQAALD 
       110        120        130        140        150
RLKVFDGIPP PYDKKKRMVV PAALKVVRLK PTRKFAYLGR LAHEVGWKYQ 
       160        170        180        190        200
AVTATLEEKR KEKAKIHYRK KKQLMRLRKQ AEKNVEKKID KYTEVLKTHG 

LLV
Length:203
Mass (Da):23,577
Last modified:January 23, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3E80D0AB77A0D406
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8J015Q8J015_HUMAN
60S ribosomal protein L13a
RPL13A RPL13a, hCG_1998057
142Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0QYS1M0QYS1_HUMAN
60S ribosomal protein L13a
RPL13A
210Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0QZU1M0QZU1_HUMAN
60S ribosomal protein L13a
RPL13A
46Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A096LPE0A0A096LPE0_HUMAN
60S ribosomal protein L13a
RPL13A
48Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
X56932 mRNA Translation: CAA40254.1
AB028893 Genomic DNA Translation: BAA88214.1
AK291120 mRNA Translation: BAF83809.1
CH471177 Genomic DNA Translation: EAW52495.1
BC000514 mRNA Translation: AAH00514.1
BC001675 mRNA Translation: AAH01675.1
BC001836 mRNA Translation: AAH01836.1
BC062537 mRNA Translation: AAH62537.1
BC065236 mRNA Translation: AAH65236.1
BC070223 mRNA Translation: AAH70223.1
BC071929 mRNA Translation: AAH71929.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS12768.1

Protein sequence database of the Protein Information Resource

More...PIRi		S29539

NCBI Reference Sequences

More...RefSeqi		NP_001257420.1, NM_001270491.1
NP_036555.1, NM_012423.3

UniGene gene-oriented nucleotide sequence clusters

More...UniGenei		Hs.523185

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000391857; ENSP00000375730; ENSG00000142541

Database of genes from NCBI RefSeq genomes

More...GeneIDi		23521

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:23521

UCSC genome browser

More...UCSCi		uc002pny.5 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X56932 mRNA Translation: CAA40254.1
AB028893 Genomic DNA Translation: BAA88214.1
AK291120 mRNA Translation: BAF83809.1
CH471177 Genomic DNA Translation: EAW52495.1
BC000514 mRNA Translation: AAH00514.1
BC001675 mRNA Translation: AAH01675.1
BC001836 mRNA Translation: AAH01836.1
BC062537 mRNA Translation: AAH62537.1
BC065236 mRNA Translation: AAH65236.1
BC070223 mRNA Translation: AAH70223.1
BC071929 mRNA Translation: AAH71929.1
CCDSiCCDS12768.1
PIRiS29539
RefSeqiNP_001257420.1, NM_001270491.1
NP_036555.1, NM_012423.3
UniGeneiHs.523185

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4UG0electron microscopy-LO1-203[»]
4V6Xelectron microscopy5.00CO1-203[»]
5AJ0electron microscopy3.50AO1-203[»]
5LKSelectron microscopy3.60LO1-203[»]
5T2Celectron microscopy3.60I1-203[»]
6EK0electron microscopy2.90LO1-203[»]
ProteinModelPortaliP40429
SMRiP40429
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi117068, 146 interactors
CORUMiP40429
IntActiP40429, 55 interactors
MINTiP40429
STRINGi9606.ENSP00000375730

Chemistry databases

DrugBankiDB02494 Alpha-Hydroxy-Beta-Phenyl-Propionic Acid
DB07374 Anisomycin
DB08437 Puromycin

Protein family/group databases

MoonProtiP40429

PTM databases

iPTMnetiP40429
PhosphoSitePlusiP40429
SwissPalmiP40429

Polymorphism and mutation databases

BioMutaiRPL13A
DMDMi730451

Proteomic databases

EPDiP40429
jPOSTiP40429
MaxQBiP40429
PaxDbiP40429
PeptideAtlasiP40429
PRIDEiP40429
ProteomicsDBi55374
TopDownProteomicsiP40429

Protocols and materials databases

The DNASU plasmid repository

More...DNASUi		23521
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000391857; ENSP00000375730; ENSG00000142541
GeneIDi23521
KEGGihsa:23521
UCSCiuc002pny.5 human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		23521
DisGeNETi23521
EuPathDBiHostDB:ENSG00000142541.16

GeneCards: human genes, protein and diseases

More...GeneCardsi		RPL13A

H-Invitational Database, human transcriptome db

More...H-InvDBi		HIX0027968
HIX0158081
HGNCiHGNC:10304 RPL13A
HPAiHPA038751
neXtProtiNX_P40429
OpenTargetsiENSG00000142541
PharmGKBiPA38122

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG3204 Eukaryota
COG0102 LUCA
GeneTreeiENSGT00390000010799
HOGENOMiHOG000225289
HOVERGENiHBG062176
InParanoidiP40429
KOiK02872
OrthoDBi1312756at2759
PhylomeDBiP40429
TreeFamiTF300159

Enzyme and pathway databases

ReactomeiR-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902 Peptide chain elongation
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823 Viral mRNA Translation
R-HSA-2408557 Selenocysteine synthesis
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72689 Formation of a pool of free 40S subunits
R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764 Eukaryotic Translation Termination
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
SIGNORiP40429

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		RPL13A human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		RPL13A

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		23521

Protein Ontology

More...PROi		PR:P40429

Gene expression databases

BgeeiENSG00000142541 Expressed in 87 organ(s), highest expression level in left ovary
CleanExiHS_RPL13A
ExpressionAtlasiP40429 baseline and differential
GenevisibleiP40429 HS

Family and domain databases

CDDicd00392 Ribosomal_L13, 1 hit
Gene3Di3.90.1180.10, 1 hit
HAMAPiMF_01366 Ribosomal_L13, 1 hit
InterProiView protein in InterPro
IPR005822 Ribosomal_L13
IPR023563 Ribosomal_L13_CS
IPR005755 Ribosomal_L13_euk/arc
IPR036899 Ribosomal_L13_sf
PANTHERiPTHR11545 PTHR11545, 1 hit
PTHR11545:SF3 PTHR11545:SF3, 1 hit
PfamiView protein in Pfam
PF00572 Ribosomal_L13, 1 hit
PIRSFiPIRSF002181 Ribosomal_L13, 1 hit
SUPFAMiSSF52161 SSF52161, 1 hit
TIGRFAMsiTIGR01077 L13_A_E, 1 hit
PROSITEiView protein in PROSITE
PS00783 RIBOSOMAL_L13, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRL13A_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P40429
Secondary accession number(s): A8K505
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: January 23, 2007
Last modified: January 16, 2019
This is version 181 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
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