RPL13A

Functionⁱ

Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex. Involved in methylation of rRNA.4 Publications

GO - Molecular functionⁱ

mRNA binding Source: GO_Central
RNA binding
Source: UniProtKB
Inferred from high throughput direct assayⁱ
- 22658674
structural constituent of ribosome Source: GO_Central

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

cellular response to interferon-gamma
Source: UniProtKB
Inferred from direct assayⁱ
- 15479637
negative regulation of formation of translation preinitiation complex
Source: UniProtKB
Inferred from direct assayⁱ
- 17218275
negative regulation of translation
Source: UniProtKB
Inferred from direct assayⁱ
- 14567916
- 23071094
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Source: Reactome
SRP-dependent cotranslational protein targeting to membrane Source: Reactome
translation
Source: UniProtKB
Non-traceable author statementⁱ
- 12962325
translational initiation Source: Reactome

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Ribonucleoprotein, Ribosomal protein
Biological process	Translation regulation

Enzyme and pathway databases

Reactomeⁱ	R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156902 Peptide chain elongation R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane R-HSA-192823 Viral mRNA Translation R-HSA-2408557 Selenocysteine synthesis R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-72689 Formation of a pool of free 40S subunits R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72764 Eukaryotic Translation Termination R-HSA-9010553 Regulation of expression of SLITs and ROBOs R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
SIGNORⁱ	P40429

Reactomeⁱ

R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902 Peptide chain elongation
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823 Viral mRNA Translation
R-HSA-2408557 Selenocysteine synthesis
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72689 Formation of a pool of free 40S subunits
R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764 Eukaryotic Translation Termination
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

SIGNORⁱ

P40429

Protein family/group databases

MoonProtⁱ	P40429

MoonProtⁱ

P40429

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: 60S ribosomal protein L13a Alternative name(s): 23 kDa highly basic protein Large ribosomal subunit protein uL131 Publication
Gene namesⁱ	Name:RPL13A
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 19

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000142541.16
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:10304 RPL13A
neXtProtⁱ	NX_P40429

Keywords - Cellular componentⁱ

Cytoplasm

Pathology & Biotechⁱ

Mutagenesis

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Mutagenesisⁱ	77	S → A: Loss of interferon-gamma induced phosphorylation. 1 Publication		1

Organism-specific databases

DisGeNET More...DisGeNETⁱ	23521
Open Targets More...OpenTargetsⁱ	ENSG00000142541
PharmGKBⁱ	PA38122

Chemistry databases

Drug and drug target database More...DrugBankⁱ	DB02494 Alpha-Hydroxy-Beta-Phenyl-Propionic Acid DB07374 Anisomycin DB08437 Puromycin

DrugBankⁱ

DB02494 Alpha-Hydroxy-Beta-Phenyl-Propionic Acid
DB07374 Anisomycin
DB08437 Puromycin

Polymorphism and mutation databases

BioMutaⁱ	RPL13A
DMDMⁱ	730451

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Initiator methionineⁱ		RemovedCombined sources3 Publications
ChainⁱPRO_0000133769	2 – 203	60S ribosomal protein L13aAdd BLAST		202

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	2	N-acetylalanineCombined sources3 Publications	1
Modified residueⁱ	59	CitrullineBy similarity	1
Modified residueⁱ	77	Phosphoserine; by ZIPK/DAPK31 Publication	1
Modified residueⁱ	140	CitrullineBy similarity	1
Modified residueⁱ	191	N6-acetyllysineCombined sources	1

Post-translational modificationⁱ

Phosphorylation at Ser-77 upon interferon-gamma treatment in monocytes involves a DAPK1-DAPK3 kinase cascade and is causing release from the ribosome, association with the GAIT complex and subsequent involvement in transcript-selective translation inhibition.2 Publications

Citrullinated by PADI4.By similarity

Keywords - PTMⁱ

Acetylation, Citrullination, Phosphoprotein

Proteomic databases

EPDⁱ	P40429
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	P40429
PaxDbⁱ	P40429
PeptideAtlas More...PeptideAtlasⁱ	P40429
PRIDEⁱ	P40429
ProteomicsDBⁱ	55374
TopDownProteomicsⁱ	P40429

PTM databases

iPTMnetⁱ	P40429
PhosphoSitePlusⁱ	P40429
SwissPalmⁱ	P40429

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000142541 Expressed in 87 organ(s), highest expression level in left ovary
CleanExⁱ	HS_RPL13A
ExpressionAtlasⁱ	P40429 baseline and differential
Genevisibleⁱ	P40429 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA038751

HPAⁱ

HPA038751

Interactionⁱ

Subunit structureⁱ

Component of the 60S ribosome. Component of the GAIT complex. Interacts with EIF4G1.1 Publication3 Publications

Protein-protein interaction databases

BioGridⁱ	117068, 142 interactors
CORUMⁱ	P40429
IntActⁱ	P40429, 52 interactors
Molecular INTeraction database More...MINTⁱ	P40429
STRINGⁱ	9606.ENSP00000375730

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P40429
SMRⁱ	P40429
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the universal ribosomal protein uL13 family.Curated

Phylogenomic databases

eggNOGⁱ	KOG3204 Eukaryota COG0102 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000010799
HOGENOMⁱ	HOG000225289
HOVERGENⁱ	HBG062176
InParanoidⁱ	P40429
KEGG Orthology (KO) More...KOⁱ	K02872
PhylomeDBⁱ	P40429
TreeFamⁱ	TF300159

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00392 Ribosomal_L13, 1 hit
Gene3Dⁱ	3.90.1180.10, 1 hit
HAMAPⁱ	MF_01366 Ribosomal_L13, 1 hit
InterProⁱ	View protein in InterPro IPR005822 Ribosomal_L13 IPR023563 Ribosomal_L13_CS IPR005755 Ribosomal_L13_euk/arc IPR036899 Ribosomal_L13_sf
PANTHERⁱ	PTHR11545 PTHR11545, 1 hit PTHR11545:SF3 PTHR11545:SF3, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00572 Ribosomal_L13, 1 hit
PIRSFⁱ	PIRSF002181 Ribosomal_L13, 1 hit
SUPFAMⁱ	SSF52161 SSF52161, 1 hit
TIGRFAMsⁱ	TIGR01077 L13_A_E, 1 hit
PROSITEⁱ	View protein in PROSITE PS00783 RIBOSOMAL_L13, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.ⁱShow all

P40429-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MAEVQVLVLD GRGHLLGRLA AIVAKQVLLG RKVVVVRCEG INISGNFYRN 
        60         70         80         90        100
KLKYLAFLRK RMNTNPSRGP YHFRAPSRIF WRTVRGMLPH KTKRGQAALD 
       110        120        130        140        150
RLKVFDGIPP PYDKKKRMVV PAALKVVRLK PTRKFAYLGR LAHEVGWKYQ 
       160        170        180        190        200
AVTATLEEKR KEKAKIHYRK KKQLMRLRKQ AEKNVEKKID KYTEVLKTHG 

LLV

Length:203

Mass (Da):23,577

Last modified:January 23, 2007 - v2

Checksum:ⁱ3E80D0AB77A0D406

GO

Computationally mapped potential isoform sequencesⁱ

There are 4 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation
Q8J015	Q8J015_HUMAN	60S ribosomal protein L13a 60S ribosomal protein L13a (Ribosomal protein L13a, isoform CRA_b)	RPL13A RPL13a, hCG_1998057	142	Annotation score:
M0QYS1	M0QYS1_HUMAN	60S ribosomal protein L13a 60S ribosomal protein L13a	RPL13A	210	Annotation score:
M0QZU1	M0QZU1_HUMAN	60S ribosomal protein L13a 60S ribosomal protein L13a	RPL13A	46	Annotation score:
A0A096LPE0	A0A096LPE0_HUMAN	60S ribosomal protein L13a 60S ribosomal protein L13a	RPL13A	48	Annotation score:

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	X56932 mRNA Translation: CAA40254.1 AB028893 Genomic DNA Translation: BAA88214.1 AK291120 mRNA Translation: BAF83809.1 CH471177 Genomic DNA Translation: EAW52495.1 BC000514 mRNA Translation: AAH00514.1 BC001675 mRNA Translation: AAH01675.1 BC001836 mRNA Translation: AAH01836.1 BC062537 mRNA Translation: AAH62537.1 BC065236 mRNA Translation: AAH65236.1 BC070223 mRNA Translation: AAH70223.1 BC071929 mRNA Translation: AAH71929.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS12768.1
PIRⁱ	S29539
NCBI Reference Sequences More...RefSeqⁱ	NP_001257420.1, NM_001270491.1 NP_036555.1, NM_012423.3
UniGeneⁱ	Hs.523185

Genome annotation databases

Ensemblⁱ	ENST00000391857; ENSP00000375730; ENSG00000142541
GeneIDⁱ	23521
KEGGⁱ	hsa:23521
UCSC genome browser More...UCSCⁱ	uc002pny.5 human

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
P40429	RPL13A isoform 2		PANTR		203	UniRef100_P40429
RPL13A isoform 2		PONAB		203
Ribosomal protein L13a		Cebus capucinus imitator		203
Ribosomal protein L13a		PANPA		203
Ribosomal protein L13a		GORGO		203
+2

Protein	Similar proteins		Species	Score	Length	Source
P40429	60S ribosomal protein L13a		RAT		203	UniRef90_P40429
60S ribosomal protein L13a		BOVIN		203
60S ribosomal protein L13a		PONAB		203
60S ribosomal protein L13a	)	CANLF		203
60S ribosomal protein L13a		MOUSE		203
+169

Protein	Similar proteins		Species	Score	Length	Source
P40429	60S ribosomal protein L13a	)	CANLF		203	UniRef50_P40429
60S ribosomal protein L13a		MACFA		203
60S ribosomal protein L13a		RAT		203
60S ribosomal protein L13a		BOVIN		203
60S ribosomal protein L13a		PONAB		203
+298

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	X56932 mRNA Translation: CAA40254.1 AB028893 Genomic DNA Translation: BAA88214.1 AK291120 mRNA Translation: BAF83809.1 CH471177 Genomic DNA Translation: EAW52495.1 BC000514 mRNA Translation: AAH00514.1 BC001675 mRNA Translation: AAH01675.1 BC001836 mRNA Translation: AAH01836.1 BC062537 mRNA Translation: AAH62537.1 BC065236 mRNA Translation: AAH65236.1 BC070223 mRNA Translation: AAH70223.1 BC071929 mRNA Translation: AAH71929.1
CCDSⁱ	CCDS12768.1
PIRⁱ	S29539
RefSeqⁱ	NP_001257420.1, NM_001270491.1 NP_036555.1, NM_012423.3
UniGeneⁱ	Hs.523185

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	4UG0	electron microscopy	-	LO	1-203	[»]
	4V6X	electron microscopy	5.00	CO	1-203	[»]
	5AJ0	electron microscopy	3.50	AO	1-203	[»]
	5LKS	electron microscopy	3.60	LO	1-203	[»]
	5T2C	electron microscopy	3.60	I	1-203	[»]
	6EK0	electron microscopy	2.90	LO	1-203	[»]
ProteinModelPortalⁱ	P40429
SMRⁱ	P40429
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	117068, 142 interactors
CORUMⁱ	P40429
IntActⁱ	P40429, 52 interactors
MINTⁱ	P40429
STRINGⁱ	9606.ENSP00000375730

Chemistry databases

DrugBankⁱ	DB02494 Alpha-Hydroxy-Beta-Phenyl-Propionic Acid DB07374 Anisomycin DB08437 Puromycin

DrugBankⁱ

DB02494 Alpha-Hydroxy-Beta-Phenyl-Propionic Acid
DB07374 Anisomycin
DB08437 Puromycin

Protein family/group databases

MoonProtⁱ	P40429

MoonProtⁱ

P40429

PTM databases

iPTMnetⁱ	P40429
PhosphoSitePlusⁱ	P40429
SwissPalmⁱ	P40429

Polymorphism and mutation databases

BioMutaⁱ	RPL13A
DMDMⁱ	730451

Proteomic databases

EPDⁱ	P40429
MaxQBⁱ	P40429
PaxDbⁱ	P40429
PeptideAtlasⁱ	P40429
PRIDEⁱ	P40429
ProteomicsDBⁱ	55374
TopDownProteomicsⁱ	P40429

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	23521
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000391857; ENSP00000375730; ENSG00000142541
GeneIDⁱ	23521
KEGGⁱ	hsa:23521
UCSCⁱ	uc002pny.5 human

Organism-specific databases

CTDⁱ	23521
DisGeNETⁱ	23521
EuPathDBⁱ	HostDB:ENSG00000142541.16
GeneCardsⁱ	RPL13A
H-InvDBⁱ	HIX0027968 HIX0158081
HGNCⁱ	HGNC:10304 RPL13A
HPAⁱ	HPA038751
neXtProtⁱ	NX_P40429
OpenTargetsⁱ	ENSG00000142541
PharmGKBⁱ	PA38122
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG3204 Eukaryota COG0102 LUCA
GeneTreeⁱ	ENSGT00390000010799
HOGENOMⁱ	HOG000225289
HOVERGENⁱ	HBG062176
InParanoidⁱ	P40429
KOⁱ	K02872
PhylomeDBⁱ	P40429
TreeFamⁱ	TF300159

Enzyme and pathway databases

Reactomeⁱ	R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156902 Peptide chain elongation R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane R-HSA-192823 Viral mRNA Translation R-HSA-2408557 Selenocysteine synthesis R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-72689 Formation of a pool of free 40S subunits R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72764 Eukaryotic Translation Termination R-HSA-9010553 Regulation of expression of SLITs and ROBOs R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
SIGNORⁱ	P40429

Reactomeⁱ

R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902 Peptide chain elongation
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823 Viral mRNA Translation
R-HSA-2408557 Selenocysteine synthesis
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72689 Formation of a pool of free 40S subunits
R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764 Eukaryotic Translation Termination
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

SIGNORⁱ

P40429

Miscellaneous databases

ChiTaRSⁱ	RPL13A human
GeneWikiⁱ	RPL13A
GenomeRNAiⁱ	23521
Protein Ontology More...PROⁱ	PR:P40429

Gene expression databases

Bgeeⁱ	ENSG00000142541 Expressed in 87 organ(s), highest expression level in left ovary
CleanExⁱ	HS_RPL13A
ExpressionAtlasⁱ	P40429 baseline and differential
Genevisibleⁱ	P40429 HS

Family and domain databases

CDDⁱ	cd00392 Ribosomal_L13, 1 hit
Gene3Dⁱ	3.90.1180.10, 1 hit
HAMAPⁱ	MF_01366 Ribosomal_L13, 1 hit
InterProⁱ	View protein in InterPro IPR005822 Ribosomal_L13 IPR023563 Ribosomal_L13_CS IPR005755 Ribosomal_L13_euk/arc IPR036899 Ribosomal_L13_sf
PANTHERⁱ	PTHR11545 PTHR11545, 1 hit PTHR11545:SF3 PTHR11545:SF3, 1 hit
Pfamⁱ	View protein in Pfam PF00572 Ribosomal_L13, 1 hit
PIRSFⁱ	PIRSF002181 Ribosomal_L13, 1 hit
SUPFAMⁱ	SSF52161 SSF52161, 1 hit
TIGRFAMsⁱ	TIGR01077 L13_A_E, 1 hit
PROSITEⁱ	View protein in PROSITE PS00783 RIBOSOMAL_L13, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	RL13A_HUMAN
Accessionⁱ	P40429Primary (citable) accession number: P40429 Secondary accession number(s): A8K505
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
	Last sequence update:	January 23, 2007
	Last modified:	September 12, 2018
	This is version 177 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

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UniProtKB - P40429 (RL13A_HUMAN)

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60S ribosomal protein L13a

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Protein family/group databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Other locations

Cytosol

Nucleus

Other locations

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Organism-specific databases

Chemistry databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Computationally mapped potential isoform sequencesi

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Chemistry databases

Protein family/group databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Computationally mapped potential isoform sequencesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ