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UniProtKB - P40325 (HUA1_YEAST)
Protein
Proline-rich protein HUA1
Gene
HUA1
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
May be involved in assembly and disassembly of the actin cytoskeleton.
1 PublicationNames & Taxonomyi
Protein namesi | Recommended name: Proline-rich protein HUA1 |
Gene namesi | Name:HUA1 Ordered Locus Names:YGR268C |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
SGDi | S000003500, HUA1 |
VEuPathDBi | FungiDB:YGR268C |
Subcellular locationi
Cytoplasm and Cytosol
- Cytoplasm 1 Publication
Other locations
- cytoplasm Source: SGD
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | RemovedCombined sources | |||
ChainiPRO_0000202865 | 2 – 198 | Proline-rich protein HUA1Add BLAST | 197 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 2 | N-acetylserineCombined sources | 1 | |
Cross-linki | 3 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)1 Publication | ||
Cross-linki | 18 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)1 Publication |
Keywords - PTMi
Acetylation, Isopeptide bond, Ubl conjugationProteomic databases
MaxQBi | P40325 |
PaxDbi | P40325 |
PRIDEi | P40325 |
PTM databases
iPTMneti | P40325 |
Interactioni
Binary interactionsi
Protein-protein interaction databases
BioGRIDi | 33518, 78 interactors |
DIPi | DIP-1987N |
IntActi | P40325, 12 interactors |
MINTi | P40325 |
STRINGi | 4932.YGR268C |
Miscellaneous databases
RNActi | P40325, protein |
Structurei
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 86 | DisorderedSequence analysisAdd BLAST | 86 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 26 | Basic and acidic residuesSequence analysisAdd BLAST | 26 | |
Compositional biasi | 40 – 70 | Polar residuesSequence analysisAdd BLAST | 31 | |
Compositional biasi | 71 – 86 | Pro residuesSequence analysisAdd BLAST | 16 |
Sequence similaritiesi
Belongs to the HUA1 family.Curated
Phylogenomic databases
eggNOGi | ENOG502S12N, Eukaryota |
HOGENOMi | CLU_078573_1_0_1 |
InParanoidi | P40325 |
OMAi | RCARRFG |
Family and domain databases
InterProi | View protein in InterPro IPR038910, Hua1-like |
PANTHERi | PTHR28031, PTHR28031, 2 hits |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P40325-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSKDTHDDEL PSYEDVIKEE ERLQSQPPRP PRPAANLAQG HQSRPHQRPS
60 70 80 90 100
TMPATSSSQT YAHSHSYTPT SSQPRPPPRP QQNPSLPWTY PPRFYCSKCG
110 120 130 140 150
NTGYKLKNGR SCKSCWRRFA PQNNVVSAPT YYTNYTMPVY TNAWQGNRPL
160 170 180 190
YVQPGDPRLG GVLCGECRGS GRTRFLLDED ICPLCHGVGR IITQPQRY
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Y07893 Genomic DNA Translation: CAA69199.1 Z73053 Genomic DNA Translation: CAA97298.1 AY558512 Genomic DNA Translation: AAS56838.1 X81072 Genomic DNA Translation: CAA56961.1 BK006941 Genomic DNA Translation: DAA08357.1 |
PIRi | S64601 |
RefSeqi | NP_011784.3, NM_001181397.3 |
Genome annotation databases
EnsemblFungii | YGR268C_mRNA; YGR268C; YGR268C |
GeneIDi | 853185 |
KEGGi | sce:YGR268C |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Y07893 Genomic DNA Translation: CAA69199.1 Z73053 Genomic DNA Translation: CAA97298.1 AY558512 Genomic DNA Translation: AAS56838.1 X81072 Genomic DNA Translation: CAA56961.1 BK006941 Genomic DNA Translation: DAA08357.1 |
PIRi | S64601 |
RefSeqi | NP_011784.3, NM_001181397.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 33518, 78 interactors |
DIPi | DIP-1987N |
IntActi | P40325, 12 interactors |
MINTi | P40325 |
STRINGi | 4932.YGR268C |
PTM databases
iPTMneti | P40325 |
Proteomic databases
MaxQBi | P40325 |
PaxDbi | P40325 |
PRIDEi | P40325 |
Genome annotation databases
EnsemblFungii | YGR268C_mRNA; YGR268C; YGR268C |
GeneIDi | 853185 |
KEGGi | sce:YGR268C |
Organism-specific databases
SGDi | S000003500, HUA1 |
VEuPathDBi | FungiDB:YGR268C |
Phylogenomic databases
eggNOGi | ENOG502S12N, Eukaryota |
HOGENOMi | CLU_078573_1_0_1 |
InParanoidi | P40325 |
OMAi | RCARRFG |
Miscellaneous databases
PROi | PR:P40325 |
RNActi | P40325, protein |
Family and domain databases
InterProi | View protein in InterPro IPR038910, Hua1-like |
PANTHERi | PTHR28031, PTHR28031, 2 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | HUA1_YEAST | |
Accessioni | P40325Primary (citable) accession number: P40325 Secondary accession number(s): D6VV46 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1995 |
Last sequence update: | October 1, 1996 | |
Last modified: | February 23, 2022 | |
This is version 148 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD - Yeast chromosome VII
Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names - SIMILARITY comments
Index of protein domains and families