Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 172 (16 Oct 2019)
Sequence version 3 (09 Nov 2004)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Alpha-taxilin

Gene

TXLNA

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in intracellular vesicle traffic and potentially in calcium-dependent exocytosis in neuroendocrine cells.

Caution

Was originally thought to be a high molecular weight interleukin (IL-14 or IL14).1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processExocytosis

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-449836 Other interleukin signaling

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Alpha-taxilin
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TXLNA
Synonyms:TXLN
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:30685 TXLNA

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
608676 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P40222

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
200081

Open Targets

More...
OpenTargetsi
ENSG00000084652

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142670668

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
P40222

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TXLNA

Domain mapping of disease mutations (DMDM)

More...
DMDMi
55584162

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001894211 – 546Alpha-taxilinAdd BLAST546

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei72PhosphoserineCombined sources1
Modified residuei515PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P40222

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P40222

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
P40222

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P40222

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P40222

PeptideAtlas

More...
PeptideAtlasi
P40222

PRoteomics IDEntifications database

More...
PRIDEi
P40222

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
55349

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P40222

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P40222

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
P40222

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitous, with much higher expression in heart, kidney, liver and pancreas.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000084652 Expressed in 210 organ(s), highest expression level in right lobe of liver

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P40222 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA045383
HPA072477

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Binds to the C-terminal coiled coil region of syntaxin family members STX1A, STX3A and STX4A, but not when these proteins are complexed with SNAP25, VAMP2 or STXBP1, suggesting that it interacts with syntaxins that do not form the SNARE complex.

2 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
Q9QYP62EBI-359793,EBI-6115874From Mus musculus.
P202903EBI-359793,EBI-1054687
Q96K175EBI-359793,EBI-6137496
Q96JN2-25EBI-359793,EBI-10171416
Q8TD31-35EBI-359793,EBI-10175300
Q018505EBI-359793,EBI-1181367
Q9C0F15EBI-359793,EBI-744115
Q8IYX8-23EBI-359793,EBI-10181988
Q96MT84EBI-359793,EBI-741977
Q05D6010EBI-359793,EBI-748597
O609414EBI-359793,EBI-740402
Q9NRA83EBI-359793,EBI-301024
Q083793EBI-359793,EBI-618309
Q9H8Y85EBI-359793,EBI-739467
Q68CZ67EBI-359793,EBI-2558217
Q9NX555EBI-359793,EBI-1048743
Q63ZY35EBI-359793,EBI-2556193
A1A4E93EBI-359793,EBI-10171552
P190125EBI-359793,EBI-739566
P359005EBI-359793,EBI-742094
Q153235EBI-359793,EBI-948001
O760153EBI-359793,EBI-1047263
Q6A1625EBI-359793,EBI-10171697
Q86VQ03EBI-359793,EBI-6658186
Q9NS73-53EBI-359793,EBI-10182361
Q9NPJ65EBI-359793,EBI-394607
P502213EBI-359793,EBI-2864512
P502223EBI-359793,EBI-748397
Q9NYP93EBI-359793,EBI-1104552
Q137652EBI-359793,EBI-712216
O147774EBI-359793,EBI-715849
Q132878EBI-359793,EBI-372942
Q96MF75EBI-359793,EBI-2557388
P371985EBI-359793,EBI-347978
Q131363EBI-359793,EBI-745426
Q9P2K33EBI-359793,EBI-743428
Q6NUQ15EBI-359793,EBI-726876
Q969G33EBI-359793,EBI-455078
Q8NA613EBI-359793,EBI-741724
Q930453EBI-359793,EBI-714194
Q166233EBI-359793,EBI-712466
Q9UHD25EBI-359793,EBI-356402
P562795EBI-359793,EBI-749995
Q9UBB95EBI-359793,EBI-1105213
Q150255EBI-359793,EBI-357849
Q13625-33EBI-359793,EBI-10175039
Q6PID64EBI-359793,EBI-2555404
Q8N3L310EBI-359793,EBI-6116822
Q8N6Y05EBI-359793,EBI-739895
Q8N1B45EBI-359793,EBI-2799833
Q9Y3C05EBI-359793,EBI-712969

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
128297, 126 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
P40222

Database of interacting proteins

More...
DIPi
DIP-27612N

Protein interaction database and analysis system

More...
IntActi
P40222, 135 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000362711

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P40222

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili186 – 491Sequence analysisAdd BLAST306

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the taxilin family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1850 Eukaryota
ENOG410XQH1 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000158303

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P40222

Identification of Orthologs from Complete Genome Data

More...
OMAi
STYCRES

Database of Orthologous Groups

More...
OrthoDBi
904532at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P40222

TreeFam database of animal gene trees

More...
TreeFami
TF318595

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026183 Taxilin_fam

The PANTHER Classification System

More...
PANTHERi
PTHR16127 PTHR16127, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF09728 Taxilin, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P40222-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKNQDKKNGA AKQSNPKSSP GQPEAGPEGA QERPSQAAPA VEAEGPGSSQ
60 70 80 90 100
APRKPEGAQA RTAQSGALRD VSEELSRQLE DILSTYCVDN NQGGPGEDGA
110 120 130 140 150
QGEPAEPEDA EKSRTYVARN GEPEPTPVVN GEKEPSKGDP NTEEIRQSDE
160 170 180 190 200
VGDRDHRRPQ EKKKAKGLGK EITLLMQTLN TLSTPEEKLA ALCKKYAELL
210 220 230 240 250
EEHRNSQKQM KLLQKKQSQL VQEKDHLRGE HSKAVLARSK LESLCRELQR
260 270 280 290 300
HNRSLKEEGV QRAREEEEKR KEVTSHFQVT LNDIQLQMEQ HNERNSKLRQ
310 320 330 340 350
ENMELAERLK KLIEQYELRE EHIDKVFKHK DLQQQLVDAK LQQAQEMLKE
360 370 380 390 400
AEERHQREKD FLLKEAVESQ RMCELMKQQE THLKQQLALY TEKFEEFQNT
410 420 430 440 450
LSKSSEVFTT FKQEMEKMTK KIKKLEKETT MYRSRWESSN KALLEMAEEK
460 470 480 490 500
TVRDKELEGL QVKIQRLEKL CRALQTERND LNKRVQDLSA GGQGSLTDSG
510 520 530 540
PERRPEGPGA QAPSSPRVTE APCYPGAPST EASGQTGPQE PTSARA
Length:546
Mass (Da):61,891
Last modified:November 9, 2004 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i698CD74F78897DF6
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH46565 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti12K → Q in CAD89951 (PubMed:17974005).Curated1
Sequence conflicti194K → R in CAD89952 (PubMed:17974005).Curated1
Sequence conflicti228R → C in AAH80578 (PubMed:15489334).Curated1
Sequence conflicti249 – 250QR → HG (PubMed:8327514).Curated2
Sequence conflicti278Q → L in CAD89952 (PubMed:17974005).Curated1
Sequence conflicti368E → A in CAD89952 (PubMed:17974005).Curated1
Sequence conflicti412K → E in CAD89951 (PubMed:17974005).Curated1
Sequence conflicti530T → A in CAD91138 (PubMed:17974005).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF516206 mRNA Translation: AAO42465.1
AL832636 mRNA Translation: CAD89951.1
AL832637 mRNA Translation: CAD89952.1
AL832338 mRNA Translation: CAD91138.1
AL049795 Genomic DNA No translation available.
CH471059 Genomic DNA Translation: EAX07565.1
CH471059 Genomic DNA Translation: EAX07566.1
BC029686 mRNA Translation: AAH29686.1
BC046565 mRNA Translation: AAH46565.1 Different initiation.
BC080578 mRNA Translation: AAH80578.1
BC103823 mRNA Translation: AAI03824.1
BC103824 mRNA Translation: AAI03825.1
L15344 mRNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS353.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A48203

NCBI Reference Sequences

More...
RefSeqi
NP_787048.1, NM_175852.3
XP_016856051.1, XM_017000562.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000373609; ENSP00000362711; ENSG00000084652
ENST00000373610; ENSP00000362712; ENSG00000084652

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
200081

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:200081

UCSC genome browser

More...
UCSCi
uc001bui.4 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF516206 mRNA Translation: AAO42465.1
AL832636 mRNA Translation: CAD89951.1
AL832637 mRNA Translation: CAD89952.1
AL832338 mRNA Translation: CAD91138.1
AL049795 Genomic DNA No translation available.
CH471059 Genomic DNA Translation: EAX07565.1
CH471059 Genomic DNA Translation: EAX07566.1
BC029686 mRNA Translation: AAH29686.1
BC046565 mRNA Translation: AAH46565.1 Different initiation.
BC080578 mRNA Translation: AAH80578.1
BC103823 mRNA Translation: AAI03824.1
BC103824 mRNA Translation: AAI03825.1
L15344 mRNA No translation available.
CCDSiCCDS353.1
PIRiA48203
RefSeqiNP_787048.1, NM_175852.3
XP_016856051.1, XM_017000562.1

3D structure databases

SMRiP40222
ModBaseiSearch...

Protein-protein interaction databases

BioGridi128297, 126 interactors
CORUMiP40222
DIPiDIP-27612N
IntActiP40222, 135 interactors
STRINGi9606.ENSP00000362711

PTM databases

iPTMnetiP40222
PhosphoSitePlusiP40222
SwissPalmiP40222

Polymorphism and mutation databases

BioMutaiTXLNA
DMDMi55584162

Proteomic databases

EPDiP40222
jPOSTiP40222
MassIVEiP40222
MaxQBiP40222
PaxDbiP40222
PeptideAtlasiP40222
PRIDEiP40222
ProteomicsDBi55349

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
200081

Genome annotation databases

EnsembliENST00000373609; ENSP00000362711; ENSG00000084652
ENST00000373610; ENSP00000362712; ENSG00000084652
GeneIDi200081
KEGGihsa:200081
UCSCiuc001bui.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
200081
DisGeNETi200081

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TXLNA
HGNCiHGNC:30685 TXLNA
HPAiHPA045383
HPA072477
MIMi608676 gene
neXtProtiNX_P40222
OpenTargetsiENSG00000084652
PharmGKBiPA142670668

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1850 Eukaryota
ENOG410XQH1 LUCA
GeneTreeiENSGT00940000158303
InParanoidiP40222
OMAiSTYCRES
OrthoDBi904532at2759
PhylomeDBiP40222
TreeFamiTF318595

Enzyme and pathway databases

ReactomeiR-HSA-449836 Other interleukin signaling

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
TXLNA human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
TXLNA

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
200081
PharosiP40222

Protein Ontology

More...
PROi
PR:P40222

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000084652 Expressed in 210 organ(s), highest expression level in right lobe of liver
GenevisibleiP40222 HS

Family and domain databases

InterProiView protein in InterPro
IPR026183 Taxilin_fam
PANTHERiPTHR16127 PTHR16127, 1 hit
PfamiView protein in Pfam
PF09728 Taxilin, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTXLNA_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P40222
Secondary accession number(s): D3DPP6
, Q5TFJ6, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: November 9, 2004
Last modified: October 16, 2019
This is version 172 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again