mdoD

Functionⁱ

Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs).

Pathwayⁱ: osmoregulated periplasmic glucan (OPG) biosynthesis

This protein is involved in the pathway osmoregulated periplasmic glucan (OPG) biosynthesis, which is part of Glycan metabolism.
View all proteins of this organism that are known to be involved in the pathway osmoregulated periplasmic glucan (OPG) biosynthesis and in Glycan metabolism.

GO - Molecular functionⁱ

carbohydrate binding Source: InterPro
catalytic activity Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

carbohydrate biosynthetic process Source: InterPro
regulation of beta-glucan biosynthetic process
Source: EcoliWiki
Inferred from direct assayⁱ
- 15175282

View the complete GO annotation on QuickGO ...

Enzyme and pathway databases

BioCycⁱ	EcoCyc:EG12859-MONOMER
UniPathwayⁱ	UPA00637

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Glucans biosynthesis protein D
Gene namesⁱ	Name:mdoD Synonyms:opgD, ydcG, yzzZ Ordered Locus Names:b1424, JW1420
Organismⁱ	Escherichia coli (strain K12)
Taxonomic identifierⁱ	83333 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › Escherichia coli
Proteomesⁱ	UP000000318 Componentⁱ: Chromosome UP000000625 Componentⁱ: Chromosome

Organism-specific databases

EcoGeneⁱ	EG12859 mdoD

EcoGeneⁱ

EG12859 mdoD

Subcellular locationⁱ

Periplasm

GO - Cellular componentⁱ

outer membrane-bounded periplasmic space
Source: EcoCyc
Inferred from direct assayⁱ

View the complete GO annotation on QuickGO ...

Keywords - Cellular componentⁱ

Periplasm

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Signal peptideⁱ	1 – 32	Tat-type signal1 PublicationAdd BLAST		32
ChainⁱPRO_0000020206	33 – 551	Glucans biosynthesis protein DAdd BLAST		519

Post-translational modificationⁱ

Exported by the Tat system. The position of the signal peptide cleavage has been experimentally proven. Can also be exported by the Sec system.

Proteomic databases

EPDⁱ	P40120
PaxDbⁱ	P40120
PRIDEⁱ	P40120

Expressionⁱ

Developmental stageⁱ

Expressed essentially during the stationary growth phase when OPG synthesis has stopped.

Interactionⁱ

Protein-protein interaction databases

BioGridⁱ	4261154, 12 interactors
IntActⁱ	P40120, 6 interactors
STRINGⁱ	316385.ECDH10B_1552

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P40120
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the OpgD/OpgG family.Curated

Keywords - Domainⁱ

Signal

Phylogenomic databases

eggNOGⁱ	ENOG4105DJ9 Bacteria COG3131 LUCA
HOGENOMⁱ	HOG000288262
InParanoidⁱ	P40120
OMAⁱ	DVQFFHV
PhylomeDBⁱ	P40120

Family and domain databases

Gene3Dⁱ	2.60.40.10, 1 hit 2.70.98.10, 1 hit
HAMAPⁱ	MF_01068 MdoD_OpgD, 1 hit
InterProⁱ	View protein in InterPro IPR011013 Gal_mutarotase_sf_dom IPR014718 GH-type_carb-bd IPR023724 Glucan_biosyn_MdoD IPR014438 Glucan_biosyn_MdoG/MdoD IPR007444 Glucan_biosyn_MdoG_C IPR013783 Ig-like_fold IPR014756 Ig_E-set IPR006311 TAT_signal IPR019546 TAT_signal_bac_arc
PANTHERⁱ	PTHR30504 PTHR30504, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF04349 MdoG, 1 hit
PIRSFⁱ	PIRSF006281 MdoG, 1 hit
SUPFAMⁱ	SSF74650 SSF74650, 1 hit SSF81296 SSF81296, 1 hit
TIGRFAMsⁱ	TIGR01409 TAT_signal_seq, 1 hit
PROSITEⁱ	View protein in PROSITE PS51318 TAT, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

P40120-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MDRRRFIKGS MAMAAVCGTS GIASLFSQAA FAADSDIADG QTQRFDFSIL 
        60         70         80         90        100
QSMAHDLAQT AWRGAPRPLP DTLATMTPQA YNSIQYDAEK SLWHNVENRQ 
       110        120        130        140        150
LDAQFFHMGM GFRRRVRMFS VDPATHLARE IHFRPELFKY NDAGVDTKQL 
       160        170        180        190        200
EGQSDLGFAG FRVFKAPELA RRDVVSFLGA SYFRAVDDTY QYGLSARGLA 
       210        220        230        240        250
IDTYTDSKEE FPDFTAFWFD TVKPGATTFT VYALLDSASI TGAYKFTIHC 
       260        270        280        290        300
EKSQVIMDVE NHLYARKDIK QLGIAPMTSM FSCGTNERRM CDTIHPQIHD 
       310        320        330        340        350
SDRLSMWRGN GEWICRPLNN PQKLQFNAYT DNNPKGFGLL QLDRDFSHYQ 
       360        370        380        390        400
DIMGWYNKRP SLWVEPRNKW GKGTIGLMEI PTTGETLDNI VCFWQPEKAV 
       410        420        430        440        450
KAGDEFAFQY RLYWSAQPPV HCPLARVMAT RTGMGGFSEG WAPGEHYPEK 
       460        470        480        490        500
WARRFAVDFV GGDLKAAAPK GIEPVITLSS GEAKQIEILY IEPIDGYRIQ 
       510        520        530        540        550
FDWYPTSDST DPVDMRMYLR CQGDAISETW LYQYFPPAPD KRQYVDDRVM 

S

Length:551

Mass (Da):62,758

Last modified:July 3, 2003 - v3

Checksum:ⁱ4FC3BE21F70D4C46

GO

Sequence cautionⁱ

The sequence BAA15046 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U00096 Genomic DNA Translation: AAC74506.3 AP009048 Genomic DNA Translation: BAA15046.1 Different initiation. X15860 Genomic DNA No translation available.
PIRⁱ	C64894
NCBI Reference Sequences More...RefSeqⁱ	NP_415941.5, NC_000913.3 WP_000375961.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaⁱ	AAC74506; AAC74506; b1424 BAA15046; BAA15046; BAA15046
GeneIDⁱ	945994
KEGGⁱ	ecj:JW1420 eco:b1424
PATRICⁱ	fig\|511145.12.peg.1487

Protein	Similar proteins		Species	Score	Length
P40120	Glucans biosynthesis protein D		ECOBW		551
Glucans biosynthesis protein D		ECODH		551
Glucans biosynthesis protein D		ECOLX		551
Glucans biosynthesis protein D		SHIBO		551
Glucans biosynthesis protein D		Escherichia coli H386		551
+12

Protein	Similar proteins		Species	Score	Length
P40120	Glucans biosynthesis protein D		SHIDS		551
Glucans biosynthesis protein D		Shigella dysenteriae WRSd3		551
Glucans biosynthesis protein D		Shigella dysenteriae 1617		551
Glucans biosynthesis protein D		ECO24		551
Glucans biosynthesis protein D		ECO57		551
+658

Protein	Similar proteins		Species	Score	Length
P40120	Glucans biosynthesis protein D		SALTI		551
UPI0000059EE8		Salmonella enterica subsp. enterica serovar Typhi str. CT18		541
UPI0009ABDE43		SALCE		448
Uncharacterized protein (Fragment)		Salmonella enterica subsp. enterica serovar Senftenberg str. A4-543		101
Glucans biosynthesis protein D		SALCH		571
+2501

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U00096 Genomic DNA Translation: AAC74506.3 AP009048 Genomic DNA Translation: BAA15046.1 Different initiation. X15860 Genomic DNA No translation available.
PIRⁱ	C64894
NCBI Reference Sequences More...RefSeqⁱ	NP_415941.5, NC_000913.3 WP_000375961.1, NZ_LN832404.1

3D structure databases

ProteinModelPortalⁱ	P40120
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	4261154, 12 interactors
IntActⁱ	P40120, 6 interactors
STRINGⁱ	316385.ECDH10B_1552

Proteomic databases

EPDⁱ	P40120
PaxDbⁱ	P40120
PRIDEⁱ	P40120

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	AAC74506; AAC74506; b1424 BAA15046; BAA15046; BAA15046
GeneIDⁱ	945994
KEGGⁱ	ecj:JW1420 eco:b1424
PATRICⁱ	fig\|511145.12.peg.1487

Organism-specific databases

EchoBASEⁱ	EB2701
EcoGeneⁱ	EG12859 mdoD

Phylogenomic databases

eggNOGⁱ	ENOG4105DJ9 Bacteria COG3131 LUCA
HOGENOMⁱ	HOG000288262
InParanoidⁱ	P40120
OMAⁱ	DVQFFHV
PhylomeDBⁱ	P40120

Enzyme and pathway databases

UniPathwayⁱ	UPA00637
BioCycⁱ	EcoCyc:EG12859-MONOMER

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:P40120

PROⁱ

PR:P40120

Family and domain databases

Gene3Dⁱ	2.60.40.10, 1 hit 2.70.98.10, 1 hit
HAMAPⁱ	MF_01068 MdoD_OpgD, 1 hit
InterProⁱ	View protein in InterPro IPR011013 Gal_mutarotase_sf_dom IPR014718 GH-type_carb-bd IPR023724 Glucan_biosyn_MdoD IPR014438 Glucan_biosyn_MdoG/MdoD IPR007444 Glucan_biosyn_MdoG_C IPR013783 Ig-like_fold IPR014756 Ig_E-set IPR006311 TAT_signal IPR019546 TAT_signal_bac_arc
PANTHERⁱ	PTHR30504 PTHR30504, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF04349 MdoG, 1 hit
PIRSFⁱ	PIRSF006281 MdoG, 1 hit
SUPFAMⁱ	SSF74650 SSF74650, 1 hit SSF81296 SSF81296, 1 hit
TIGRFAMsⁱ	TIGR01409 TAT_signal_seq, 1 hit
PROSITEⁱ	View protein in PROSITE PS51318 TAT, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	OPGD_ECOLI
Accessionⁱ	P40120Primary (citable) accession number: P40120 Secondary accession number(s): P46134, P76098, P77631
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
	Last sequence update:	July 3, 2003
	Last modified:	March 28, 2018
	This is version 131 of the entry and version 3 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Prokaryotic Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Direct protein sequencing, Reference proteome

Documents

Escherichia coli
Escherichia coli (strain K12): entries and cross-references to EcoGene
PATHWAY comments
Index of metabolic and biosynthesis pathways
SIMILARITY comments
Index of protein domains and families

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P40120 (OPGD_ECOLI)

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Glucans biosynthesis protein D

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: osmoregulated periplasmic glucan (OPG) biosynthesis

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

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Functionⁱ

Pathwayⁱ: osmoregulated periplasmic glucan (OPG) biosynthesis

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequence cautionⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ