The new UniProt website is here!
Take me to UniProt BETA
UniProtKB - P40120 (OPGD_ECOLI)
Protein
Glucans biosynthesis protein D
Gene
mdoD
Organism
Escherichia coli (strain K12)
Status
Functioni
Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs).
: osmoregulated periplasmic glucan (OPG) biosynthesis Pathwayi
This protein is involved in the pathway osmoregulated periplasmic glucan (OPG) biosynthesis, which is part of Glycan metabolism.View all proteins of this organism that are known to be involved in the pathway osmoregulated periplasmic glucan (OPG) biosynthesis and in Glycan metabolism.
GO - Molecular functioni
- carbohydrate binding Source: InterPro
- catalytic activity Source: InterPro
GO - Biological processi
- beta-glucan biosynthetic process Source: GO_Central
Enzyme and pathway databases
BioCyci | EcoCyc:EG12859-MONOMER |
UniPathwayi | UPA00637 |
Names & Taxonomyi
Protein namesi | Recommended name: Glucans biosynthesis protein D |
Gene namesi | Name:mdoD Synonyms:opgD, ydcG, yzzZ Ordered Locus Names:b1424, JW1420 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Other locations
Other locations
- outer membrane-bounded periplasmic space Source: EcoCyc
Keywords - Cellular componenti
PeriplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 32 | Tat-type signal1 PublicationAdd BLAST | 32 | |
ChainiPRO_0000020206 | 33 – 551 | Glucans biosynthesis protein DAdd BLAST | 519 |
Post-translational modificationi
Exported by the Tat system. The position of the signal peptide cleavage has been experimentally proven. Can also be exported by the Sec system.
Proteomic databases
jPOSTi | P40120 |
PaxDbi | P40120 |
PRIDEi | P40120 |
Expressioni
Developmental stagei
Expressed essentially during the stationary growth phase when OPG synthesis has stopped.
Interactioni
Protein-protein interaction databases
BioGRIDi | 4261154, 12 interactors |
IntActi | P40120, 6 interactors |
STRINGi | 511145.b1424 |
Family & Domainsi
Sequence similaritiesi
Belongs to the OpgD/OpgG family.Curated
Keywords - Domaini
SignalPhylogenomic databases
eggNOGi | COG3131, Bacteria |
HOGENOMi | CLU_023403_2_0_6 |
InParanoidi | P40120 |
OMAi | DVQFFHV |
PhylomeDBi | P40120 |
Family and domain databases
Gene3Di | 2.60.40.10, 1 hit 2.70.98.10, 1 hit |
HAMAPi | MF_01068, MdoD_OpgD, 1 hit |
InterProi | View protein in InterPro IPR011013, Gal_mutarotase_sf_dom IPR014718, GH-type_carb-bd IPR023724, Glucan_biosyn_MdoD IPR014438, Glucan_biosyn_MdoG/MdoD IPR007444, Glucan_biosyn_MdoG_C IPR013783, Ig-like_fold IPR014756, Ig_E-set IPR006311, TAT_signal IPR019546, TAT_signal_bac_arc |
PANTHERi | PTHR30504, PTHR30504, 1 hit |
Pfami | View protein in Pfam PF04349, MdoG, 1 hit |
PIRSFi | PIRSF006281, MdoG, 1 hit |
SUPFAMi | SSF74650, SSF74650, 1 hit SSF81296, SSF81296, 1 hit |
TIGRFAMsi | TIGR01409, TAT_signal_seq, 1 hit |
PROSITEi | View protein in PROSITE PS51318, TAT, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P40120-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDRRRFIKGS MAMAAVCGTS GIASLFSQAA FAADSDIADG QTQRFDFSIL
60 70 80 90 100
QSMAHDLAQT AWRGAPRPLP DTLATMTPQA YNSIQYDAEK SLWHNVENRQ
110 120 130 140 150
LDAQFFHMGM GFRRRVRMFS VDPATHLARE IHFRPELFKY NDAGVDTKQL
160 170 180 190 200
EGQSDLGFAG FRVFKAPELA RRDVVSFLGA SYFRAVDDTY QYGLSARGLA
210 220 230 240 250
IDTYTDSKEE FPDFTAFWFD TVKPGATTFT VYALLDSASI TGAYKFTIHC
260 270 280 290 300
EKSQVIMDVE NHLYARKDIK QLGIAPMTSM FSCGTNERRM CDTIHPQIHD
310 320 330 340 350
SDRLSMWRGN GEWICRPLNN PQKLQFNAYT DNNPKGFGLL QLDRDFSHYQ
360 370 380 390 400
DIMGWYNKRP SLWVEPRNKW GKGTIGLMEI PTTGETLDNI VCFWQPEKAV
410 420 430 440 450
KAGDEFAFQY RLYWSAQPPV HCPLARVMAT RTGMGGFSEG WAPGEHYPEK
460 470 480 490 500
WARRFAVDFV GGDLKAAAPK GIEPVITLSS GEAKQIEILY IEPIDGYRIQ
510 520 530 540 550
FDWYPTSDST DPVDMRMYLR CQGDAISETW LYQYFPPAPD KRQYVDDRVM
S
Sequence cautioni
The sequence BAA15046 differs from that shown. Reason: Erroneous initiation.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC74506.3 AP009048 Genomic DNA Translation: BAA15046.1 Different initiation. X15860 Genomic DNA No translation available. |
PIRi | C64894 |
RefSeqi | NP_415941.5, NC_000913.3 WP_000375961.1, NZ_SSZK01000021.1 |
Genome annotation databases
EnsemblBacteriai | AAC74506; AAC74506; b1424 BAA15046; BAA15046; BAA15046 |
GeneIDi | 945994 |
KEGGi | ecj:JW1420 eco:b1424 |
PATRICi | fig|511145.12.peg.1487 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC74506.3 AP009048 Genomic DNA Translation: BAA15046.1 Different initiation. X15860 Genomic DNA No translation available. |
PIRi | C64894 |
RefSeqi | NP_415941.5, NC_000913.3 WP_000375961.1, NZ_SSZK01000021.1 |
3D structure databases
AlphaFoldDBi | P40120 |
SMRi | P40120 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4261154, 12 interactors |
IntActi | P40120, 6 interactors |
STRINGi | 511145.b1424 |
Proteomic databases
jPOSTi | P40120 |
PaxDbi | P40120 |
PRIDEi | P40120 |
Genome annotation databases
EnsemblBacteriai | AAC74506; AAC74506; b1424 BAA15046; BAA15046; BAA15046 |
GeneIDi | 945994 |
KEGGi | ecj:JW1420 eco:b1424 |
PATRICi | fig|511145.12.peg.1487 |
Organism-specific databases
EchoBASEi | EB2701 |
Phylogenomic databases
eggNOGi | COG3131, Bacteria |
HOGENOMi | CLU_023403_2_0_6 |
InParanoidi | P40120 |
OMAi | DVQFFHV |
PhylomeDBi | P40120 |
Enzyme and pathway databases
UniPathwayi | UPA00637 |
BioCyci | EcoCyc:EG12859-MONOMER |
Miscellaneous databases
PROi | PR:P40120 |
Family and domain databases
Gene3Di | 2.60.40.10, 1 hit 2.70.98.10, 1 hit |
HAMAPi | MF_01068, MdoD_OpgD, 1 hit |
InterProi | View protein in InterPro IPR011013, Gal_mutarotase_sf_dom IPR014718, GH-type_carb-bd IPR023724, Glucan_biosyn_MdoD IPR014438, Glucan_biosyn_MdoG/MdoD IPR007444, Glucan_biosyn_MdoG_C IPR013783, Ig-like_fold IPR014756, Ig_E-set IPR006311, TAT_signal IPR019546, TAT_signal_bac_arc |
PANTHERi | PTHR30504, PTHR30504, 1 hit |
Pfami | View protein in Pfam PF04349, MdoG, 1 hit |
PIRSFi | PIRSF006281, MdoG, 1 hit |
SUPFAMi | SSF74650, SSF74650, 1 hit SSF81296, SSF81296, 1 hit |
TIGRFAMsi | TIGR01409, TAT_signal_seq, 1 hit |
PROSITEi | View protein in PROSITE PS51318, TAT, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | OPGD_ECOLI | |
Accessioni | P40120Primary (citable) accession number: P40120 Secondary accession number(s): P46134, P76098, P77631 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1995 |
Last sequence update: | July 3, 2003 | |
Last modified: | May 25, 2022 | |
This is version 152 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Direct protein sequencing, Reference proteomeDocuments
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families