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Protein

Aldehyde dehydrogenase

Gene

CLAH10

Organism
Davidiella tassiana (Mycosphaerella tassiana) (Cladosporium herbarum)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

An aldehyde + NAD+ + H2O = a carboxylate + NADH.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei263By similarity1
Active sitei296By similarity1

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
LigandNAD

Names & Taxonomyi

Protein namesi
Recommended name:
Aldehyde dehydrogenase (EC:1.2.1.3)
Short name:
ALDDH
Short name:
ALDH
Alternative name(s):
Allergen Cla h 3
Allergen Cla h III
Allergen: Cla h 10
Gene namesi
Name:CLAH10
Synonyms:CLAH3
OrganismiDavidiella tassiana (Mycosphaerella tassiana) (Cladosporium herbarum)
Taxonomic identifieri29918 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaDothideomycetesDothideomycetidaeCapnodialesCladosporiaceaeCladosporium

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human.1 Publication

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei218 Cla h 10
3201 Cla h 10.0101

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000564371 – 496Aldehyde dehydrogenaseAdd BLAST496

Proteomic databases

PRIDEiP40108

Structurei

3D structure databases

ProteinModelPortaliP40108
SMRiP40108
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldehyde dehydrogenase family.Curated

Family and domain databases

Gene3Di3.40.309.10, 1 hit
3.40.605.10, 2 hits
InterProiView protein in InterPro
IPR016161 Ald_DH/histidinol_DH
IPR016163 Ald_DH_C
IPR016160 Ald_DH_CS_CYS
IPR029510 Ald_DH_CS_GLU
IPR016162 Ald_DH_N
IPR015590 Aldehyde_DH_dom
PfamiView protein in Pfam
PF00171 Aldedh, 1 hit
SUPFAMiSSF53720 SSF53720, 1 hit
PROSITEiView protein in PROSITE
PS00070 ALDEHYDE_DEHYDR_CYS, 1 hit
PS00687 ALDEHYDE_DEHYDR_GLU, 1 hit

Sequencei

Sequence statusi: Complete.

P40108-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTSVQLETPH SGKYEQPTGL FINNEFVKGQ EGKTFDVINP SDESVITQVH
60 70 80 90 100
EATEKDVDIA VAAARKAFEG SWRQETPENR GKLLNNLANL FEKNIDLLAA
110 120 130 140 150
VESLDNGKAI SMAKGDISMC VGCLRYYGGW ADKITGKVID TTPDTFNYVK
160 170 180 190 200
KEPIGVCGQI IPWNFPLLMW AWKIGPAIAC GNTVVLKTAE QTPLGGLVAA
210 220 230 240 250
SLVKEAGFPP GVINVISGFG KVAGAALSSH MDVDKVAFTG STVVGRTILK
260 270 280 290 300
AAASSNLKKV TLELGGKSPN IVFEDADIDN AISWVNFGIF FNHGQCCCAG
310 320 330 340 350
SRVYVQESIY DKFVQKFKER AQKNVVGDPF AADTFQGPQV SKVQFDRIME
360 370 380 390 400
YIQAGKDAGA TVETGGKRKG DKGYFIEPTI FSNVTEDMKI VKEEIFGPVC
410 420 430 440 450
SIAKFKTKED AIKLGNASTY GLAAAVHTKN LNTAIEVSNA LKAGTVWVNT
460 470 480 490
YNTLHHQMPF GGYKESGIGR ELGEDALANY TQTKTVSIRL GDALFG
Length:496
Mass (Da):53,554
Last modified:June 13, 2006 - v2
Checksum:iD938B5D0D9B26999
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X78228 mRNA Translation: CAA55072.2
PIRiS43114

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X78228 mRNA Translation: CAA55072.2
PIRiS43114

3D structure databases

ProteinModelPortaliP40108
SMRiP40108
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei218 Cla h 10
3201 Cla h 10.0101

Proteomic databases

PRIDEiP40108

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.40.309.10, 1 hit
3.40.605.10, 2 hits
InterProiView protein in InterPro
IPR016161 Ald_DH/histidinol_DH
IPR016163 Ald_DH_C
IPR016160 Ald_DH_CS_CYS
IPR029510 Ald_DH_CS_GLU
IPR016162 Ald_DH_N
IPR015590 Aldehyde_DH_dom
PfamiView protein in Pfam
PF00171 Aldedh, 1 hit
SUPFAMiSSF53720 SSF53720, 1 hit
PROSITEiView protein in PROSITE
PS00070 ALDEHYDE_DEHYDR_CYS, 1 hit
PS00687 ALDEHYDE_DEHYDR_GLU, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiALDH_DAVTA
AccessioniPrimary (citable) accession number: P40108
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: June 13, 2006
Last modified: July 18, 2018
This is version 83 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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