UniProtKB - P39932 (STL1_YEAST)
Protein
Sugar transporter STL1
Gene
STL1
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
GO - Molecular functioni
- carbohydrate:proton symporter activity Source: GO_Central
- solute:proton symporter activity Source: SGD
GO - Biological processi
- carbohydrate transport Source: GO_Central
- glycerol transport Source: SGD
- transmembrane transport Source: SGD
Keywordsi
Biological process | Sugar transport, Transport |
Protein family/group databases
TCDBi | 2.A.1.1.38, the major facilitator superfamily (mfs) |
Names & Taxonomyi
Protein namesi | Recommended name: Sugar transporter STL1 |
Gene namesi | Name:STL1 Ordered Locus Names:YDR536W ORF Names:D9719.39 |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
SGDi | S000002944, STL1 |
VEuPathDBi | FungiDB:YDR536W |
Subcellular locationi
Other locations
Plasma Membrane
- plasma membrane Source: SGD
Vacuole
- fungal-type vacuole Source: SGD
Other locations
- cell periphery Source: SGD
- integral component of membrane Source: UniProtKB-KW
- membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 29 | CytoplasmicSequence analysisAdd BLAST | 29 | |
Transmembranei | 30 – 50 | Helical; Name=1Sequence analysisAdd BLAST | 21 | |
Topological domaini | 51 – 79 | ExtracellularSequence analysisAdd BLAST | 29 | |
Transmembranei | 80 – 100 | Helical; Name=2Sequence analysisAdd BLAST | 21 | |
Topological domaini | 101 – 107 | CytoplasmicSequence analysis | 7 | |
Transmembranei | 108 – 128 | Helical; Name=3Sequence analysisAdd BLAST | 21 | |
Topological domaini | 129 | ExtracellularSequence analysis | 1 | |
Transmembranei | 130 – 150 | Helical; Name=4Sequence analysisAdd BLAST | 21 | |
Topological domaini | 151 – 168 | CytoplasmicSequence analysisAdd BLAST | 18 | |
Transmembranei | 169 – 189 | Helical; Name=5Sequence analysisAdd BLAST | 21 | |
Topological domaini | 190 – 203 | ExtracellularSequence analysisAdd BLAST | 14 | |
Transmembranei | 204 – 224 | Helical; Name=6Sequence analysisAdd BLAST | 21 | |
Topological domaini | 225 – 291 | CytoplasmicSequence analysisAdd BLAST | 67 | |
Transmembranei | 292 – 312 | Helical; Name=7Sequence analysisAdd BLAST | 21 | |
Topological domaini | 313 – 330 | ExtracellularSequence analysisAdd BLAST | 18 | |
Transmembranei | 331 – 351 | Helical; Name=8Sequence analysisAdd BLAST | 21 | |
Topological domaini | 352 – 358 | CytoplasmicSequence analysis | 7 | |
Transmembranei | 359 – 379 | Helical; Name=9Sequence analysisAdd BLAST | 21 | |
Topological domaini | 380 – 389 | ExtracellularSequence analysis | 10 | |
Transmembranei | 390 – 410 | Helical; Name=10Sequence analysisAdd BLAST | 21 | |
Topological domaini | 411 – 426 | CytoplasmicSequence analysisAdd BLAST | 16 | |
Transmembranei | 427 – 447 | Helical; Name=11Sequence analysisAdd BLAST | 21 | |
Topological domaini | 448 – 453 | ExtracellularSequence analysis | 6 | |
Transmembranei | 454 – 474 | Helical; Name=12Sequence analysisAdd BLAST | 21 | |
Topological domaini | 475 – 569 | CytoplasmicSequence analysisAdd BLAST | 95 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000050461 | 1 – 569 | Sugar transporter STL1Add BLAST | 569 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 197 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 319 | N-linked (GlcNAc...) asparagineSequence analysis | 1 |
Keywords - PTMi
GlycoproteinProteomic databases
PaxDbi | P39932 |
PRIDEi | P39932 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 32584, 117 interactors |
DIPi | DIP-5275N |
IntActi | P39932, 2 interactors |
STRINGi | 4932.YDR536W |
Miscellaneous databases
RNActi | P39932, protein |
Family & Domainsi
Sequence similaritiesi
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]Curated
Keywords - Domaini
Repeat, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0254, Eukaryota |
HOGENOMi | CLU_001265_30_3_1 |
InParanoidi | P39932 |
OMAi | WSAPCVE |
Family and domain databases
InterProi | View protein in InterPro IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR003663, Sugar/inositol_transpt IPR005829, Sugar_transporter_CS |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
PRINTSi | PR00171, SUGRTRNSPORT |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00879, SP, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00216, SUGAR_TRANSPORT_1, 1 hit |
i Sequence
Sequence statusi: Complete.
P39932-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKDLKLSNFK GKFISRTSHW GLTGKKLRYF ITIASMTGFS LFGYDQGLMA
60 70 80 90 100
SLITGKQFNY EFPATKENGD HDRHATVVQG ATTSCYELGC FAGSLFVMFC
110 120 130 140 150
GERIGRKPLI LMGSVITIIG AVISTCAFRG YWALGQFIIG RVVTGVGTGL
160 170 180 190 200
NTSTIPVWQS EMSKAENRGL LVNLEGSTIA FGTMIAYWID FGLSYTNSSV
210 220 230 240 250
QWRFPVSMQI VFALFLLAFM IKLPESPRWL ISQSRTEEAR YLVGTLDDAD
260 270 280 290 300
PNDEEVITEV AMLHDAVNRT KHEKHSLSSL FSRGRSQNLQ RALIAASTQF
310 320 330 340 350
FQQFTGCNAA IYYSTVLFNK TIKLDYRLSM IIGGVFATIY ALSTIGSFFL
360 370 380 390 400
IEKLGRRKLF LLGATGQAVS FTITFACLVK ENKENARGAA VGLFLFITFF
410 420 430 440 450
GLSLLSLPWI YPPEIASMKV RASTNAFSTC TNWLCNFAVV MFTPIFIGQS
460 470 480 490 500
GWGCYLFFAV MNYLYIPVIF FFYPETAGRS LEEIDIIFAK AYEDGTQPWR
510 520 530 540 550
VANHLPKLSL QEVEDHANAL GSYDDEMEKE DFGEDRVEDT YNQINGDNSS
560
SSSNIKNEDT VNDKANFEG
Sequence cautioni
The sequence AAA57229 differs from that shown. Reason: Frameshift.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 237 | E → G in AAU09713 (PubMed:17322287).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L07492 Genomic DNA Translation: AAA57229.1 Frameshift. U33057 Genomic DNA Translation: AAB64975.1 AY723796 Genomic DNA Translation: AAU09713.1 BK006938 Genomic DNA Translation: DAA12366.1 |
PIRi | S69591 |
RefSeqi | NP_010825.3, NM_001180844.3 |
Genome annotation databases
EnsemblFungii | YDR536W_mRNA; YDR536W; YDR536W |
GeneIDi | 852149 |
KEGGi | sce:YDR536W |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L07492 Genomic DNA Translation: AAA57229.1 Frameshift. U33057 Genomic DNA Translation: AAB64975.1 AY723796 Genomic DNA Translation: AAU09713.1 BK006938 Genomic DNA Translation: DAA12366.1 |
PIRi | S69591 |
RefSeqi | NP_010825.3, NM_001180844.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 32584, 117 interactors |
DIPi | DIP-5275N |
IntActi | P39932, 2 interactors |
STRINGi | 4932.YDR536W |
Protein family/group databases
TCDBi | 2.A.1.1.38, the major facilitator superfamily (mfs) |
Proteomic databases
PaxDbi | P39932 |
PRIDEi | P39932 |
Genome annotation databases
EnsemblFungii | YDR536W_mRNA; YDR536W; YDR536W |
GeneIDi | 852149 |
KEGGi | sce:YDR536W |
Organism-specific databases
SGDi | S000002944, STL1 |
VEuPathDBi | FungiDB:YDR536W |
Phylogenomic databases
eggNOGi | KOG0254, Eukaryota |
HOGENOMi | CLU_001265_30_3_1 |
InParanoidi | P39932 |
OMAi | WSAPCVE |
Miscellaneous databases
PROi | PR:P39932 |
RNActi | P39932, protein |
Family and domain databases
InterProi | View protein in InterPro IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR003663, Sugar/inositol_transpt IPR005829, Sugar_transporter_CS |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
PRINTSi | PR00171, SUGRTRNSPORT |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00879, SP, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00216, SUGAR_TRANSPORT_1, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | STL1_YEAST | |
Accessioni | P39932Primary (citable) accession number: P39932 Secondary accession number(s): D6VTF6, E9P950 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1995 |
Last sequence update: | October 1, 1996 | |
Last modified: | April 7, 2021 | |
This is version 169 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD - Yeast chromosome IV
Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names - SIMILARITY comments
Index of protein domains and families