UniProtKB - P39832 (ZNUB_ECOLI)
Protein
High-affinity zinc uptake system membrane protein ZnuB
Gene
znuB
Organism
Escherichia coli (strain K12)
Status
Functioni
Involved in the high-affinity zinc uptake transport system.
GO - Molecular functioni
- ATPase-coupled transmembrane transporter activity Source: InterPro
- high-affinity zinc transmembrane transporter activity Source: EcoCyc
GO - Biological processi
- response to zinc ion Source: GO_Central
- zinc ion import across plasma membrane Source: EcoCyc
Keywordsi
Biological process | Ion transport, Transport, Zinc transport |
Ligand | Zinc |
Enzyme and pathway databases
BioCyci | EcoCyc:ZNUB-MONOMER MetaCyc:ZNUB-MONOMER |
Protein family/group databases
TCDBi | 3.A.1.15.5, the atp-binding cassette (abc) superfamily |
Names & Taxonomyi
Protein namesi | Recommended name: High-affinity zinc uptake system membrane protein ZnuB |
Gene namesi | Name:znuB Synonyms:yebI Ordered Locus Names:b1859, JW1848 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 7 | PeriplasmicSequence analysis | 7 | |
Transmembranei | 8 – 28 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 29 – 53 | CytoplasmicSequence analysisAdd BLAST | 25 | |
Transmembranei | 54 – 74 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 75 – 83 | PeriplasmicSequence analysis | 9 | |
Transmembranei | 84 – 104 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 105 – 121 | CytoplasmicSequence analysisAdd BLAST | 17 | |
Transmembranei | 122 – 142 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 143 – 177 | PeriplasmicSequence analysisAdd BLAST | 35 | |
Transmembranei | 178 – 198 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 199 – 213 | CytoplasmicSequence analysisAdd BLAST | 15 | |
Transmembranei | 214 – 234 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 235 | PeriplasmicSequence analysis | 1 | |
Transmembranei | 236 – 256 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 257 – 261 | CytoplasmicSequence analysis | 5 |
GO - Cellular componenti
- ATP-binding cassette (ABC) transporter complex Source: InterPro
- integral component of plasma membrane Source: InterPro
- plasma membrane Source: EcoCyc
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000171161 | 1 – 261 | High-affinity zinc uptake system membrane protein ZnuBAdd BLAST | 261 |
Proteomic databases
PaxDbi | P39832 |
PRIDEi | P39832 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4260881, 11 interactors |
ComplexPortali | CPX-4407, Zinc ABC transporter complex |
STRINGi | 511145.b1859 |
Family & Domainsi
Sequence similaritiesi
Belongs to the ABC-3 integral membrane protein family.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG1108, Bacteria |
HOGENOMi | CLU_028808_3_2_6 |
InParanoidi | P39832 |
PhylomeDBi | P39832 |
Family and domain databases
Gene3Di | 1.10.3470.10, 1 hit |
InterProi | View protein in InterPro IPR037294, ABC_BtuC-like IPR001626, ABC_TroCD |
PANTHERi | PTHR30477, PTHR30477, 1 hit |
Pfami | View protein in Pfam PF00950, ABC-3, 1 hit |
SUPFAMi | SSF81345, SSF81345, 1 hit |
i Sequence
Sequence statusi: Complete.
P39832-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MIELLFPGWL AGIMLACAAG PLGSFVVWRR MSYFGDTLAH ASLLGVAFGL
60 70 80 90 100
LLDVNPFYAV IAVTLLLAGG LVWLEKRPQL AIDTLLGIMA HSALSLGLVV
110 120 130 140 150
VSLMSNIRVD LMAYLFGDLL AVTPEDLISI AIGVVIVVAI LFWQWRNLLS
160 170 180 190 200
MTISPDLAFV DGVKLQRVKL LLMLVTALTI GVAMKFVGAL IITSLLIIPA
210 220 230 240 250
ATARRFARTP EQMAGVAVLV GMVAVTGGLT FSAVYDTPAG PSVVLCAALL
260
FILSMMKKQA S
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC74929.1 AP009048 Genomic DNA Translation: BAA15667.1 U38702 Genomic DNA Translation: AAA81031.1 M21298 Genomic DNA No translation available. |
PIRi | C64948 |
RefSeqi | NP_416373.1, NC_000913.3 WP_000571480.1, NZ_SSZK01000001.1 |
Genome annotation databases
EnsemblBacteriai | AAC74929; AAC74929; b1859 BAA15667; BAA15667; BAA15667 |
GeneIDi | 946372 |
KEGGi | ecj:JW1848 eco:b1859 |
PATRICi | fig|1411691.4.peg.389 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC74929.1 AP009048 Genomic DNA Translation: BAA15667.1 U38702 Genomic DNA Translation: AAA81031.1 M21298 Genomic DNA No translation available. |
PIRi | C64948 |
RefSeqi | NP_416373.1, NC_000913.3 WP_000571480.1, NZ_SSZK01000001.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 4260881, 11 interactors |
ComplexPortali | CPX-4407, Zinc ABC transporter complex |
STRINGi | 511145.b1859 |
Protein family/group databases
TCDBi | 3.A.1.15.5, the atp-binding cassette (abc) superfamily |
Proteomic databases
PaxDbi | P39832 |
PRIDEi | P39832 |
Genome annotation databases
EnsemblBacteriai | AAC74929; AAC74929; b1859 BAA15667; BAA15667; BAA15667 |
GeneIDi | 946372 |
KEGGi | ecj:JW1848 eco:b1859 |
PATRICi | fig|1411691.4.peg.389 |
Organism-specific databases
EchoBASEi | EB2271 |
Phylogenomic databases
eggNOGi | COG1108, Bacteria |
HOGENOMi | CLU_028808_3_2_6 |
InParanoidi | P39832 |
PhylomeDBi | P39832 |
Enzyme and pathway databases
BioCyci | EcoCyc:ZNUB-MONOMER MetaCyc:ZNUB-MONOMER |
Miscellaneous databases
PROi | PR:P39832 |
Family and domain databases
Gene3Di | 1.10.3470.10, 1 hit |
InterProi | View protein in InterPro IPR037294, ABC_BtuC-like IPR001626, ABC_TroCD |
PANTHERi | PTHR30477, PTHR30477, 1 hit |
Pfami | View protein in Pfam PF00950, ABC-3, 1 hit |
SUPFAMi | SSF81345, SSF81345, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | ZNUB_ECOLI | |
Accessioni | P39832Primary (citable) accession number: P39832 Secondary accession number(s): P76286 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1995 |
Last sequence update: | November 1, 1997 | |
Last modified: | December 2, 2020 | |
This is version 148 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families