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Entry version 189 (02 Jun 2021)
Sequence version 4 (29 Aug 2001)
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Protein

Sensor protein TorS

Gene

torS

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Member of the two-component regulatory system TorS/TorR involved in the anaerobic utilization of trimethylamine-N-oxide (TMAO). Detects the presence of TMAO in the medium and, in response, activates TorR via a four-step phosphorelay. When TMAO is removed, TorS can dephosphorylate TorR, probably by a reverse phosphorelay involving His-860 and Asp-733.

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. EC:2.7.13.3

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

Inhibited by TorC apocytochrome.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • ATP binding Source: UniProtKB-KW
  • identical protein binding Source: IntAct
  • phosphoprotein phosphatase activity Source: EcoCyc
  • phosphorelay sensor kinase activity Source: EcoCyc

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinase, Transferase
Biological processTwo-component regulatory system
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
EcoCyc:TORS-MONOMER

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
2.7.13.3, 2026

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Sensor protein TorS (EC:2.7.13.3)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:torS
Synonyms:yccI
Ordered Locus Names:b0993, JW5135
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli (strain K12)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83333 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 8CytoplasmicSequence analysis8
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei9 – 29HelicalSequence analysisAdd BLAST21
Topological domaini30 – 332PeriplasmicSequence analysisAdd BLAST303
Transmembranei333 – 353HelicalSequence analysisAdd BLAST21
Topological domaini354 – 914CytoplasmicSequence analysisAdd BLAST561

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi453H → Q: Loss of activity. 1 Publication1
Mutagenesisi733D → A or E: Loss of activity. 1 Publication1
Mutagenesisi860H → Q: Decrease in activity. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000748881 – 914Sensor protein TorSAdd BLAST914

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei453Phosphohistidine; by autocatalysisCurated1
Modified residuei7334-aspartylphosphateCurated1
Modified residuei860PhosphohistidineCurated1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Activation requires a sequential transfer of a phosphate group from a His in the primary transmitter domain, to an Asp in the receiver domain and to a His in the secondary transmitter domain.

Keywords - PTMi

Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P39453

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P39453

PRoteomics IDEntifications database

More...
PRIDEi
P39453

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P39453

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

May form homomultimers. Seems to interact with TorT and TorC apocytochrome.

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

P39453
With#Exp.IntAct
itself2EBI-9149134,EBI-9149134

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
4262839, 4 interactors
849969, 1 interactor

Database of interacting proteins

More...
DIPi
DIP-11017N

Protein interaction database and analysis system

More...
IntActi
P39453, 1 interactor

STRING: functional protein association networks

More...
STRINGi
511145.b0993

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1914
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P39453

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
P39453

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini354 – 407HAMPPROSITE-ProRule annotationAdd BLAST54
Domaini450 – 664Histidine kinasePROSITE-ProRule annotationAdd BLAST215
Domaini683 – 798Response regulatoryPROSITE-ProRule annotationAdd BLAST116
Domaini821 – 914HPtPROSITE-ProRule annotationAdd BLAST94

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG0784, Bacteria
COG2198, Bacteria
COG2205, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000445_40_1_6

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P39453

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P39453

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00082, HisKA, 1 hit
cd00088, HPT, 1 hit
cd16172, TorS_sensor_domain, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.120.160, 1 hit
1.20.58.920, 1 hit
3.30.565.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011006, CheY-like_superfamily
IPR003660, HAMP_dom
IPR003594, HATPase_C
IPR036890, HATPase_C_sf
IPR005467, His_kinase_dom
IPR003661, HisK_dim/P
IPR036097, HisK_dim/P_sf
IPR036641, HPT_dom_sf
IPR037952, Sensor_TorS
IPR004358, Sig_transdc_His_kin-like_C
IPR008207, Sig_transdc_His_kin_Hpt_dom
IPR014302, Sig_transdc_His_kinase_TorS
IPR001789, Sig_transdc_resp-reg_receiver
IPR038188, TorS_sensor_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00672, HAMP, 1 hit
PF02518, HATPase_c, 1 hit
PF00512, HisKA, 1 hit
PF01627, Hpt, 1 hit
PF00072, Response_reg, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF036437, HK_TorS, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00344, BCTRLSENSOR

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00304, HAMP, 1 hit
SM00387, HATPase_c, 1 hit
SM00388, HisKA, 1 hit
SM00073, HPT, 1 hit
SM00448, REC, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47226, SSF47226, 1 hit
SSF47384, SSF47384, 1 hit
SSF52172, SSF52172, 1 hit
SSF55874, SSF55874, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR02956, TMAO_torS, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50885, HAMP, 1 hit
PS50109, HIS_KIN, 1 hit
PS50894, HPT, 1 hit
PS50110, RESPONSE_REGULATORY, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P39453-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNLTLTRRLW MGFALMALLT LTSTLVGWYN LRFISQVEKD NTQALIPTMN
60 70 80 90 100
MARQLSEASA WELFAAQNLT SADNEKMWQA QGRMLTAQSL KINALLQALR
110 120 130 140 150
EQGFDTTAIE QQEQEISRSL RQQGELVGQR LQLRQQQQQL SQQIVAAADE
160 170 180 190 200
IARLAQGQAN NATTSAGATQ AGIYDLIEQD QRQAAESALD RLIDIDLEYV
210 220 230 240 250
NQMNELRLSA LRVQQMVMNL GLEQIQKNAP TLEKQLNNAV KILQRRQIRI
260 270 280 290 300
EDPGVRAQVA TTLTTVSQYS DLLALYQQDS EISNHLQTLA QNNIAQFAQF
310 320 330 340 350
SSEVSQLVDT IELRNQHGLA HLEKASARGQ YSLLLLGMVS LCALILILWR
360 370 380 390 400
VVYRSVTRPL AEQTQALQRL LDGDIDSPFP ETAGVRELDT IGRLMDAFRS
410 420 430 440 450
NVHALNRHRE QLAAQVKART AELQELVIEH RQARAEAEKA SQAKSAFLAA
460 470 480 490 500
MSHEIRTPLY GILGTAQLLA DNPALNAQRD DLRAITDSGE SLLTILNDIL
510 520 530 540 550
DYSAIEAGGK NVSVSDEPFE PRPLLESTLQ LMSGRVKGRP IRLATAIADD
560 570 580 590 600
MPCALMGDPR RIRQVITNLL SNALRFTDEG YIILRSRTDG EQWLVEVEDS
610 620 630 640 650
GCGIDPAKLA EIFQPFVQVS GKRGGTGLGL TISSRLAQAM GGELSATSTP
660 670 680 690 700
EVGSCFCLRL PLRVATAPVP KTVNQAVRLD GLRLLLIEDN PLTQRITIEM
710 720 730 740 750
LKTSGAQIVA VGNAAQALET LQNSEPFAAA LVDFDLPDID GITLARQLAQ
760 770 780 790 800
QYPSLVLIGF SAHVIDETLR QRTSSLFRGI IPKPVPREVL GQLLAHYLQL
810 820 830 840 850
QVNNDQSLDV SQLNEDAQLM GTEKIHEWLV LFTQHALPLL DEIDIARASQ
860 870 880 890 900
DSEKIKRAAH QLKSSCSSLG MHIASQLCAQ LEQQPLSAPL PHEEITRSVA
910
ALEAWLHKKD LNAI
Length:914
Mass (Da):101,024
Last modified:August 29, 2001 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i45D66BD027B69FCD
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CAA63920 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti771 – 772QR → HG in CAA63920 (PubMed:8809780).Curated2

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural varianti295 – 297Missing in torS726; constitutively active. 3
Natural varianti408H → L in torS729; partial activation. 1
Natural varianti414A → P in torS13; partial activation. 1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X94231 Genomic DNA Translation: CAA63920.1 Different initiation.
U00096 Genomic DNA Translation: AAC74078.2
AP009048 Genomic DNA Translation: BAA36135.2

Protein sequence database of the Protein Information Resource

More...
PIRi
G64840

NCBI Reference Sequences

More...
RefSeqi
NP_415513.2, NC_000913.3
WP_001300633.1, NZ_LN832404.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAC74078; AAC74078; b0993
BAA36135; BAA36135; BAA36135

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
945595

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ecj:JW5135
eco:b0993

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|511145.12.peg.1029

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X94231 Genomic DNA Translation: CAA63920.1 Different initiation.
U00096 Genomic DNA Translation: AAC74078.2
AP009048 Genomic DNA Translation: BAA36135.2
PIRiG64840
RefSeqiNP_415513.2, NC_000913.3
WP_001300633.1, NZ_LN832404.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3I9WX-ray2.70A35-320[»]
SMRiP39453
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi4262839, 4 interactors
849969, 1 interactor
DIPiDIP-11017N
IntActiP39453, 1 interactor
STRINGi511145.b0993

PTM databases

iPTMnetiP39453

Proteomic databases

jPOSTiP39453
PaxDbiP39453
PRIDEiP39453

Genome annotation databases

EnsemblBacteriaiAAC74078; AAC74078; b0993
BAA36135; BAA36135; BAA36135
GeneIDi945595
KEGGiecj:JW5135
eco:b0993
PATRICifig|511145.12.peg.1029

Organism-specific databases

EchoBASE - an integrated post-genomic database for E. coli

More...
EchoBASEi
EB2501

Phylogenomic databases

eggNOGiCOG0784, Bacteria
COG2198, Bacteria
COG2205, Bacteria
HOGENOMiCLU_000445_40_1_6
InParanoidiP39453
PhylomeDBiP39453

Enzyme and pathway databases

BioCyciEcoCyc:TORS-MONOMER
BRENDAi2.7.13.3, 2026

Miscellaneous databases

EvolutionaryTraceiP39453

Protein Ontology

More...
PROi
PR:P39453

Family and domain databases

CDDicd00082, HisKA, 1 hit
cd00088, HPT, 1 hit
cd16172, TorS_sensor_domain, 1 hit
Gene3Di1.20.120.160, 1 hit
1.20.58.920, 1 hit
3.30.565.10, 1 hit
InterProiView protein in InterPro
IPR011006, CheY-like_superfamily
IPR003660, HAMP_dom
IPR003594, HATPase_C
IPR036890, HATPase_C_sf
IPR005467, His_kinase_dom
IPR003661, HisK_dim/P
IPR036097, HisK_dim/P_sf
IPR036641, HPT_dom_sf
IPR037952, Sensor_TorS
IPR004358, Sig_transdc_His_kin-like_C
IPR008207, Sig_transdc_His_kin_Hpt_dom
IPR014302, Sig_transdc_His_kinase_TorS
IPR001789, Sig_transdc_resp-reg_receiver
IPR038188, TorS_sensor_sf
PfamiView protein in Pfam
PF00672, HAMP, 1 hit
PF02518, HATPase_c, 1 hit
PF00512, HisKA, 1 hit
PF01627, Hpt, 1 hit
PF00072, Response_reg, 1 hit
PIRSFiPIRSF036437, HK_TorS, 1 hit
PRINTSiPR00344, BCTRLSENSOR
SMARTiView protein in SMART
SM00304, HAMP, 1 hit
SM00387, HATPase_c, 1 hit
SM00388, HisKA, 1 hit
SM00073, HPT, 1 hit
SM00448, REC, 1 hit
SUPFAMiSSF47226, SSF47226, 1 hit
SSF47384, SSF47384, 1 hit
SSF52172, SSF52172, 1 hit
SSF55874, SSF55874, 1 hit
TIGRFAMsiTIGR02956, TMAO_torS, 1 hit
PROSITEiView protein in PROSITE
PS50885, HAMP, 1 hit
PS50109, HIS_KIN, 1 hit
PS50894, HPT, 1 hit
PS50110, RESPONSE_REGULATORY, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTORS_ECOLI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P39453
Secondary accession number(s): P75887
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: August 29, 2001
Last modified: June 2, 2021
This is version 189 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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