UniProtKB - P39353 (YJHC_ECOLI)
Protein
Uncharacterized oxidoreductase YjhC
Gene
yjhC
Organism
Escherichia coli (strain K12)
Status
Functioni
GO - Molecular functioni
- oxidoreductase activity Source: UniProtKB-KW
GO - Biological processi
- cellular response to DNA damage stimulus Source: EcoliWiki
Keywordsi
Molecular function | Oxidoreductase |
Enzyme and pathway databases
BioCyci | EcoCyc:G7901-MONOMER |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:yjhC Ordered Locus Names:b4280, JW5769 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000091781 | 1 – 372 | Uncharacterized oxidoreductase YjhCAdd BLAST | 372 |
Proteomic databases
jPOSTi | P39353 |
PaxDbi | P39353 |
PRIDEi | P39353 |
Expressioni
Inductioni
Negatively regulated by the transcriptional repressor NanR. Induced by N-acetylneuraminate, via inactivation of NanR.1 Publication
Interactioni
Binary interactionsi
P39353
With | #Exp. | IntAct |
---|---|---|
metN [P30750] | 3 | EBI-542024,EBI-541886 |
Protein-protein interaction databases
BioGRIDi | 4261650, 8 interactors 853090, 2 interactors |
DIPi | DIP-12617N |
IntActi | P39353, 2 interactors |
STRINGi | 511145.b4280 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P39353 |
ModBasei | Search... |
PDBe-KBi | Search... |
Family & Domainsi
Sequence similaritiesi
Belongs to the Gfo/Idh/MocA family.Curated
Phylogenomic databases
eggNOGi | COG0673, Bacteria |
HOGENOMi | CLU_023194_16_0_6 |
InParanoidi | P39353 |
PhylomeDBi | P39353 |
Family and domain databases
InterProi | View protein in InterPro IPR004104, Gfo/Idh/MocA-like_OxRdtase_C IPR036291, NAD(P)-bd_dom_sf IPR000683, Oxidoreductase_N |
Pfami | View protein in Pfam PF01408, GFO_IDH_MocA, 1 hit PF02894, GFO_IDH_MocA_C, 1 hit |
SUPFAMi | SSF51735, SSF51735, 1 hit |
i Sequence
Sequence statusi: Complete.
P39353-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MINYGVVGVG YFGAELARFM NMHDNAKITC VYDPENGENI ARELQCINMS
60 70 80 90 100
SLDALVSSKL VDCVIVATPN YLHKEPVIKA AKNKKHVFCE KPIALSYEDC
110 120 130 140 150
VDMVKACKEA GVTFMAGHIM NFFNGVQYAR KLIKEGVIGE ILSCHTKRNG
160 170 180 190 200
WENKQERLSW KKMKEQSGGH LYHHIHELDC VQHLLGEIPE TVTMIGGNLA
210 220 230 240 250
HSGPGFGNED DMLFMTLEFP SGKLATLEWG SAFNWPEHYV IINGTKGSIK
260 270 280 290 300
IDMQETAGSL RIGGQTKHFL VHETQEEDDD RRKGNMTSEM DGAIAYGHPG
310 320 330 340 350
KKTPLWLASL IRKETLFLHN ILCGAKPEED YIDLLNGEAA MSAIATADAA
360 370
TLSRSQDRKV KISEIIKHTS VM
Sequence cautioni
The sequence AAA97176 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U14003 Genomic DNA Translation: AAA97176.1 Different initiation. U00096 Genomic DNA Translation: AAC77236.2 AP009048 Genomic DNA Translation: BAE78274.1 |
PIRi | S56505 |
RefSeqi | NP_418700.2, NC_000913.3 WP_000611568.1, NZ_SSUV01000014.1 |
Genome annotation databases
EnsemblBacteriai | AAC77236; AAC77236; b4280 BAE78274; BAE78274; BAE78274 |
GeneIDi | 57730680 948808 |
KEGGi | ecj:JW5769 eco:b4280 |
PATRICi | fig|1411691.4.peg.2423 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U14003 Genomic DNA Translation: AAA97176.1 Different initiation. U00096 Genomic DNA Translation: AAC77236.2 AP009048 Genomic DNA Translation: BAE78274.1 |
PIRi | S56505 |
RefSeqi | NP_418700.2, NC_000913.3 WP_000611568.1, NZ_SSUV01000014.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
6O15 | X-ray | 1.35 | A/B | 1-372 | [»] | |
SMRi | P39353 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 4261650, 8 interactors 853090, 2 interactors |
DIPi | DIP-12617N |
IntActi | P39353, 2 interactors |
STRINGi | 511145.b4280 |
Proteomic databases
jPOSTi | P39353 |
PaxDbi | P39353 |
PRIDEi | P39353 |
Genome annotation databases
EnsemblBacteriai | AAC77236; AAC77236; b4280 BAE78274; BAE78274; BAE78274 |
GeneIDi | 57730680 948808 |
KEGGi | ecj:JW5769 eco:b4280 |
PATRICi | fig|1411691.4.peg.2423 |
Organism-specific databases
EchoBASEi | EB2433 |
Phylogenomic databases
eggNOGi | COG0673, Bacteria |
HOGENOMi | CLU_023194_16_0_6 |
InParanoidi | P39353 |
PhylomeDBi | P39353 |
Enzyme and pathway databases
BioCyci | EcoCyc:G7901-MONOMER |
Miscellaneous databases
PROi | PR:P39353 |
Family and domain databases
InterProi | View protein in InterPro IPR004104, Gfo/Idh/MocA-like_OxRdtase_C IPR036291, NAD(P)-bd_dom_sf IPR000683, Oxidoreductase_N |
Pfami | View protein in Pfam PF01408, GFO_IDH_MocA, 1 hit PF02894, GFO_IDH_MocA_C, 1 hit |
SUPFAMi | SSF51735, SSF51735, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | YJHC_ECOLI | |
Accessioni | P39353Primary (citable) accession number: P39353 Secondary accession number(s): Q2M632 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1995 |
Last sequence update: | December 15, 1998 | |
Last modified: | April 7, 2021 | |
This is version 143 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families