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UniProtKB - P39338 (YJGN_ECOLI)

Entry version 121 (29 Sep 2021)
Sequence version 5 (11 Oct 2004)
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Protein

Inner membrane protein YjgN

Gene

yjgN

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...BioCyci		EcoCyc:G7887-MONOMER

Protein family/group databases

Transport Classification Database

More...TCDBi		9.B.318.1.1, the yjgj or duf898 (duf898) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Inner membrane protein YjgN
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:yjgN
Ordered Locus Names:b4257, JW5759
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli (strain K12)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83333 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 24CytoplasmicSequence analysisAdd BLAST24
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei25 – 45HelicalSequence analysisAdd BLAST21
Topological domaini46 – 73PeriplasmicSequence analysisAdd BLAST28
Transmembranei74 – 94HelicalSequence analysisAdd BLAST21
Topological domaini95CytoplasmicSequence analysis1
Transmembranei96 – 116HelicalSequence analysisAdd BLAST21
Topological domaini117 – 142PeriplasmicSequence analysisAdd BLAST26
Transmembranei143 – 163HelicalSequence analysisAdd BLAST21
Topological domaini164 – 175CytoplasmicSequence analysisAdd BLAST12
Transmembranei176 – 196HelicalSequence analysisAdd BLAST21
Topological domaini197 – 228PeriplasmicSequence analysisAdd BLAST32
Transmembranei229 – 249HelicalSequence analysisAdd BLAST21
Topological domaini250 – 278CytoplasmicSequence analysisAdd BLAST29
Transmembranei279 – 299HelicalSequence analysisAdd BLAST21
Topological domaini300 – 333PeriplasmicSequence analysisAdd BLAST34
Transmembranei334 – 354HelicalSequence analysisAdd BLAST21
Topological domaini355 – 398CytoplasmicSequence analysisAdd BLAST44

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001697681 – 398Inner membrane protein YjgNAdd BLAST398

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P39338

PRoteomics IDEntifications database

More...PRIDEi		P39338

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		4263245, 4 interactors

STRING: functional protein association networks

More...STRINGi		511145.b4257

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		COG4269, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_049287_2_0_6

Database for complete collections of gene phylogenies

More...PhylomeDBi		P39338

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR010295, DUF898

Pfam protein domain database

More...Pfami		View protein in Pfam
PF05987, DUF898, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P39338-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAQVINEMDV PSHSFVFHGT GERYFLICVV NVLLTIITLG IYLPWALMKC 
        60         70         80         90        100
KRYLYANMEV NGQRFSYGIT GGNVFVSCLF FVFFYFAILM TVSADMPLVG 
       110        120        130        140        150
CVLTLLLLVL LIFMAAKGLR HQALMTSLNG VRFSFNCSMK GFWWVTFFLP 
       160        170        180        190        200
ILMAIGMGTV FFISTKMLPA NSSSSVIISM VLMAIVGIVS IGIFNGTLYS 
       210        220        230        240        250
LVMSFLWSNT SFGIHRFKVK LDTTYCIKYA ILAFLALLPF LAVAGYIIFD 
       260        270        280        290        300
QILNAYDSSV YANDDIENLQ QFMEMQRKMI IAQLIYYFGI AVSTSYLTVS 
       310        320        330        340        350
LRNHFMSNLS LNDGRIRFRL TLTYHGMLYR MCALVVISGI TGGLAYPLLK 
       360        370        380        390 
IWMIDWQAKN TYLLGDLDDL PLINKEEQPD KGFLASISRG VMPSLPFL
Length:398
Mass (Da):44,900
Last modified:October 11, 2004 - v5
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7F78F19C29E49342
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAA97154 differs from that shown. Reason: Frameshift.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
U14003 Genomic DNA Translation: AAA97153.1 Frameshift.
U14003 Genomic DNA Translation: AAA97154.1 Frameshift.
U00096 Genomic DNA Translation: AAT48246.1
AP009048 Genomic DNA Translation: BAE78254.1

Protein sequence database of the Protein Information Resource

More...PIRi		D65238
S56482

NCBI Reference Sequences

More...RefSeqi		WP_000079634.1, NZ_LN832404.1
YP_026288.1, NC_000913.3

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		AAT48246; AAT48246; b4257
BAE78254; BAE78254; BAE78254

Database of genes from NCBI RefSeq genomes

More...GeneIDi		948784

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		ecj:JW5759
eco:b4257

Pathosystems Resource Integration Center (PATRIC)

More...PATRICi		fig|1411691.4.peg.2447

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U14003 Genomic DNA Translation: AAA97153.1 Frameshift.
U14003 Genomic DNA Translation: AAA97154.1 Frameshift.
U00096 Genomic DNA Translation: AAT48246.1
AP009048 Genomic DNA Translation: BAE78254.1
PIRiD65238
S56482
RefSeqiWP_000079634.1, NZ_LN832404.1
YP_026288.1, NC_000913.3

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi4263245, 4 interactors
STRINGi511145.b4257

Protein family/group databases

TCDBi9.B.318.1.1, the yjgj or duf898 (duf898) family

Proteomic databases

PaxDbiP39338
PRIDEiP39338

Genome annotation databases

EnsemblBacteriaiAAT48246; AAT48246; b4257
BAE78254; BAE78254; BAE78254
GeneIDi948784
KEGGiecj:JW5759
eco:b4257
PATRICifig|1411691.4.peg.2447

Organism-specific databases

EchoBASE - an integrated post-genomic database for E. coli

More...EchoBASEi		EB2423

Phylogenomic databases

eggNOGiCOG4269, Bacteria
HOGENOMiCLU_049287_2_0_6
PhylomeDBiP39338

Enzyme and pathway databases

BioCyciEcoCyc:G7887-MONOMER

Miscellaneous databases

Protein Ontology

More...PROi		PR:P39338

Family and domain databases

InterProiView protein in InterPro
IPR010295, DUF898
PfamiView protein in Pfam
PF05987, DUF898, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYJGN_ECOLI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P39338
Secondary accession number(s): P39339
, P76811, Q2M652, Q6BEW8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: October 11, 2004
Last modified: September 29, 2021
This is version 121 of the entry and version 5 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome
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