UniProtKB - P39328 (YTFT_ECOLI)
Protein
Galactofuranose transporter permease protein YtfT
Gene
ytfT
Organism
Escherichia coli (strain K12)
Status
Functioni
Part of the ABC transporter complex YtfQRT-YjfF involved in galactofuranose transport (Probable). Probably responsible for the translocation of the substrate across the membrane (Probable).Curated
GO - Molecular functioni
- transmembrane transporter activity Source: InterPro
GO - Biological processi
- carbohydrate transport Source: UniProtKB-KW
Keywordsi
Biological process | Sugar transport, Transport |
Enzyme and pathway databases
BioCyci | EcoCyc:YTFT-MONOMER MetaCyc:YTFT-MONOMER |
Protein family/group databases
TCDBi | 3.A.1.2.25, the atp-binding cassette (abc) superfamily |
Names & Taxonomyi
Protein namesi | Recommended name: Galactofuranose transporter permease protein YtfTCurated |
Gene namesi | Name:ytfT Ordered Locus Names:b4230, JW5753 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
- Cell inner membrane 1 Publication; Multi-pass membrane protein Sequence analysis
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 25 | CytoplasmicCuratedAdd BLAST | 25 | |
Transmembranei | 26 – 46 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 47 – 65 | PeriplasmicCuratedAdd BLAST | 19 | |
Transmembranei | 66 – 86 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 87 – 107 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 108 | PeriplasmicCurated | 1 | |
Transmembranei | 109 – 129 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 130 – 136 | CytoplasmicCurated | 7 | |
Transmembranei | 137 – 157 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 158 – 174 | PeriplasmicCuratedAdd BLAST | 17 | |
Transmembranei | 175 – 195 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 196 – 223 | CytoplasmicCuratedAdd BLAST | 28 | |
Transmembranei | 224 – 244 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 245 – 255 | PeriplasmicCuratedAdd BLAST | 11 | |
Transmembranei | 256 – 276 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 277 – 281 | CytoplasmicCurated | 5 | |
Transmembranei | 282 – 302 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 303 – 323 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 324 – 341 | Cytoplasmic1 PublicationAdd BLAST | 18 |
GO - Cellular componenti
- integral component of membrane Source: GO_Central
- integral component of plasma membrane Source: EcoCyc
- plasma membrane Source: EcoCyc
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000060265 | 1 – 341 | Galactofuranose transporter permease protein YtfTAdd BLAST | 341 |
Proteomic databases
PaxDbi | P39328 |
PRIDEi | P39328 |
Interactioni
Subunit structurei
The complex is composed of two ATP-binding proteins (YtfR), two transmembrane proteins (YtfT and YjfF) and a solute-binding protein (YtfQ).
1 PublicationBinary interactionsi
P39328
With | #Exp. | IntAct |
---|---|---|
murC [P17952] | 3 | EBI-554774,EBI-554607 |
Protein-protein interaction databases
BioGRIDi | 4259314, 8 interactors 853034, 1 interactor |
ComplexPortali | CPX-4323, Galactofuranose ABC transporter complex |
DIPi | DIP-12946N |
IntActi | P39328, 1 interactor |
STRINGi | 511145.b4230 |
Family & Domainsi
Sequence similaritiesi
Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG1172, Bacteria |
HOGENOMi | CLU_028880_3_0_6 |
InParanoidi | P39328 |
PhylomeDBi | P39328 |
Family and domain databases
InterProi | View protein in InterPro IPR001851, ABC_transp_permease |
Pfami | View protein in Pfam PF02653, BPD_transp_2, 1 hit |
i Sequence
Sequence statusi: Complete.
P39328-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MMPQSLPDTT TPKRRFRWPT GMPQLVALLL VLLVDSLVAP HFWQVVLQDG
60 70 80 90 100
RLFGSPIDIL NRAAPVALLA IGMTLVIATG GIDLSVGAVM AIAGATTAAM
110 120 130 140 150
TVAGFSLPIV LLSALGTGIL AGLWNGILVA ILKIQPFVAT LILMVAGRGV
160 170 180 190 200
AQLITAGQIV TFNSPDLSWF GSGSLLFLPT PVIIAVLTLI LFWLLTRKTA
210 220 230 240 250
LGMFIEAVGI NIRAAKNAGV NTRIIVMLTY VLSGLCAAIA GIIVAADIRG
260 270 280 290 300
ADANNAGLWL ELDAILAVVI GGGSLMGGRF NLLLSVVGAL IIQGMNTGIL
310 320 330 340
LSGFPPEMNQ VVKAVVVLCV LIVQSQRFIS LIKGVRSRDK T
Sequence cautioni
The sequence BAE78230 differs from that shown. Reason: Erroneous initiation.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U14003 Genomic DNA Translation: AAA97127.1 U00096 Genomic DNA Translation: AAC77187.3 AP009048 Genomic DNA Translation: BAE78230.1 Different initiation. |
PIRi | S56456 |
RefSeqi | NP_418651.3, NC_000913.3 |
Genome annotation databases
EnsemblBacteriai | AAC77187; AAC77187; b4230 BAE78230; BAE78230; BAE78230 |
GeneIDi | 948743 |
KEGGi | ecj:JW5753 eco:b4230 |
PATRICi | fig|511145.12.peg.4361 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U14003 Genomic DNA Translation: AAA97127.1 U00096 Genomic DNA Translation: AAC77187.3 AP009048 Genomic DNA Translation: BAE78230.1 Different initiation. |
PIRi | S56456 |
RefSeqi | NP_418651.3, NC_000913.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 4259314, 8 interactors 853034, 1 interactor |
ComplexPortali | CPX-4323, Galactofuranose ABC transporter complex |
DIPi | DIP-12946N |
IntActi | P39328, 1 interactor |
STRINGi | 511145.b4230 |
Protein family/group databases
TCDBi | 3.A.1.2.25, the atp-binding cassette (abc) superfamily |
Proteomic databases
PaxDbi | P39328 |
PRIDEi | P39328 |
Genome annotation databases
EnsemblBacteriai | AAC77187; AAC77187; b4230 BAE78230; BAE78230; BAE78230 |
GeneIDi | 948743 |
KEGGi | ecj:JW5753 eco:b4230 |
PATRICi | fig|511145.12.peg.4361 |
Organism-specific databases
EchoBASEi | EB2411 |
Phylogenomic databases
eggNOGi | COG1172, Bacteria |
HOGENOMi | CLU_028880_3_0_6 |
InParanoidi | P39328 |
PhylomeDBi | P39328 |
Enzyme and pathway databases
BioCyci | EcoCyc:YTFT-MONOMER MetaCyc:YTFT-MONOMER |
Miscellaneous databases
PROi | PR:P39328 |
Family and domain databases
InterProi | View protein in InterPro IPR001851, ABC_transp_permease |
Pfami | View protein in Pfam PF02653, BPD_transp_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | YTFT_ECOLI | |
Accessioni | P39328Primary (citable) accession number: P39328 Secondary accession number(s): Q2M676 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1995 |
Last sequence update: | February 1, 1995 | |
Last modified: | December 2, 2020 | |
This is version 155 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families