UniProtKB - P39206 (CAIE_ECOLI)
Protein
Carnitine operon protein CaiE
Gene
caiE
Organism
Escherichia coli (strain K12)
Status
Functioni
Overproduction of CaiE stimulates the activity of CaiB and CaiD.1 Publication
: carnitine metabolism Pathwayi
This protein is involved in the pathway carnitine metabolism, which is part of Amine and polyamine metabolism.View all proteins of this organism that are known to be involved in the pathway carnitine metabolism and in Amine and polyamine metabolism.
GO - Molecular functioni
- transferase activity Source: UniProtKB-KW
GO - Biological processi
- carnitine metabolic process Source: EcoCyc
Keywordsi
Molecular function | Transferase |
Enzyme and pathway databases
BioCyci | EcoCyc:CAIE-MONOMER MetaCyc:CAIE-MONOMER |
UniPathwayi | UPA00117 |
Names & Taxonomyi
Protein namesi | Recommended name: Carnitine operon protein CaiE |
Gene namesi | Name:caiE Ordered Locus Names:b0035, JW5004 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000068719 | 1 – 196 | Carnitine operon protein CaiEAdd BLAST | 196 |
Proteomic databases
PaxDbi | P39206 |
PRIDEi | P39206 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4261465, 163 interactors |
STRINGi | 511145.b0035 |
Family & Domainsi
Sequence similaritiesi
Belongs to the transferase hexapeptide repeat family.Curated
Keywords - Domaini
RepeatPhylogenomic databases
eggNOGi | COG0663, Bacteria |
HOGENOMi | CLU_064827_4_2_6 |
InParanoidi | P39206 |
PhylomeDBi | P39206 |
Family and domain databases
HAMAPi | MF_01525, CaiE, 1 hit |
InterProi | View protein in InterPro IPR023446, CaiE IPR001451, Hexapep IPR011004, Trimer_LpxA-like_sf |
Pfami | View protein in Pfam PF00132, Hexapep, 2 hits |
SUPFAMi | SSF51161, SSF51161, 1 hit |
i Sequence
Sequence statusi: Complete.
P39206-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSYYAFEGLI PVVHPTAFVH PSAVLIGDVI VGAGVYIGPL ASLRGDYGRL
60 70 80 90 100
IVQAGANIQD GCIMHGYCDT DTIVGENGHI GHGAILHGCL IGRDALVGMN
110 120 130 140 150
SVIMDGAVIG EESIVAAMSF VKAGFRGEKR QLLMGTPARA VRNVSDDELH
160 170 180 190
WKRLNTKEYQ DLVGRCHVSL HETQPLRQME ENRPRLQGTT DVTPKR
Sequence cautioni
The sequence CAA52115 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural varianti | 54 | A → T in strain: O44:K74. | 1 | |
Natural varianti | 90 | L → V in strain: O44:K74. | 1 | |
Natural varianti | 126 | R → H in strain: O44:K74. | 1 | |
Natural varianti | 143 | N → S in strain: O44:K74. | 1 | |
Natural varianti | 153 | R → Q in strain: O44:K74. | 1 | |
Natural varianti | 168 | V → A in strain: O44:K74. | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X73904 Genomic DNA Translation: CAA52115.1 Different initiation. U00096 Genomic DNA Translation: AAC73146.2 AP009048 Genomic DNA Translation: BAB96604.2 |
PIRi | C64724 |
RefSeqi | NP_414577.2, NC_000913.3 WP_000122871.1, NZ_LN832404.1 |
Genome annotation databases
EnsemblBacteriai | AAC73146; AAC73146; b0035 BAB96604; BAB96604; BAB96604 |
GeneIDi | 948999 |
KEGGi | ecj:JW5004 eco:b0035 |
PATRICi | fig|1411691.4.peg.2248 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X73904 Genomic DNA Translation: CAA52115.1 Different initiation. U00096 Genomic DNA Translation: AAC73146.2 AP009048 Genomic DNA Translation: BAB96604.2 |
PIRi | C64724 |
RefSeqi | NP_414577.2, NC_000913.3 WP_000122871.1, NZ_LN832404.1 |
3D structure databases
SMRi | P39206 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4261465, 163 interactors |
STRINGi | 511145.b0035 |
Proteomic databases
PaxDbi | P39206 |
PRIDEi | P39206 |
Genome annotation databases
EnsemblBacteriai | AAC73146; AAC73146; b0035 BAB96604; BAB96604; BAB96604 |
GeneIDi | 948999 |
KEGGi | ecj:JW5004 eco:b0035 |
PATRICi | fig|1411691.4.peg.2248 |
Organism-specific databases
EchoBASEi | EB2492 |
Phylogenomic databases
eggNOGi | COG0663, Bacteria |
HOGENOMi | CLU_064827_4_2_6 |
InParanoidi | P39206 |
PhylomeDBi | P39206 |
Enzyme and pathway databases
UniPathwayi | UPA00117 |
BioCyci | EcoCyc:CAIE-MONOMER MetaCyc:CAIE-MONOMER |
Miscellaneous databases
PROi | PR:P39206 |
Family and domain databases
HAMAPi | MF_01525, CaiE, 1 hit |
InterProi | View protein in InterPro IPR023446, CaiE IPR001451, Hexapep IPR011004, Trimer_LpxA-like_sf |
Pfami | View protein in Pfam PF00132, Hexapep, 2 hits |
SUPFAMi | SSF51161, SSF51161, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | CAIE_ECOLI | |
Accessioni | P39206Primary (citable) accession number: P39206 Secondary accession number(s): Q8KMY1 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1995 |
Last sequence update: | December 1, 2000 | |
Last modified: | December 2, 2020 | |
This is version 134 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families