UniProtKB - P39173 (YEAD_ECOLI)
Protein
Putative glucose-6-phosphate 1-epimerase
Gene
yeaD
Organism
Escherichia coli (strain K12)
Status
Functioni
Catalytic activityi
- EC:5.1.3.15By similarity
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 74 | SubstrateBy similarity | 1 | |
Binding sitei | 99 | SubstrateBy similarity | 1 | |
Active sitei | 164 | By similarity | 1 | |
Binding sitei | 208 | SubstrateBy similarity | 1 | |
Active sitei | 267 | By similarity | 1 |
GO - Molecular functioni
- carbohydrate binding Source: InterPro
- glucose-6-phosphate 1-epimerase activity Source: GO_Central
GO - Biological processi
- carbohydrate metabolic process Source: InterPro
- cellular response to DNA damage stimulus Source: EcoliWiki
Keywordsi
Molecular function | Isomerase |
Enzyme and pathway databases
BioCyci | EcoCyc:G6966-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Putative glucose-6-phosphate 1-epimeraseBy similarity (EC:5.1.3.15By similarity)Alternative name(s): Putative D-hexose-6-phosphate mutarotaseBy similarity Unknown protein from 2D-page spots T26/PR37 |
Gene namesi | Name:yeaD Synonyms:yzzQ Ordered Locus Names:b1780, JW1769 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000213036 | 1 – 294 | Putative glucose-6-phosphate 1-epimeraseAdd BLAST | 294 |
Proteomic databases
jPOSTi | P39173 |
PaxDbi | P39173 |
PRIDEi | P39173 |
Interactioni
Subunit structurei
Monomer in solution.
1 PublicationProtein-protein interaction databases
BioGRIDi | 4260309, 34 interactors |
IntActi | P39173, 2 interactors |
STRINGi | 511145.b1780 |
Family & Domainsi
Sequence similaritiesi
Belongs to the glucose-6-phosphate 1-epimerase family.Curated
Phylogenomic databases
eggNOGi | COG0676, Bacteria |
HOGENOMi | CLU_048345_4_1_6 |
InParanoidi | P39173 |
PhylomeDBi | P39173 |
Family and domain databases
CDDi | cd09020, D-hex-6-P-epi_like, 1 hit |
Gene3Di | 2.70.98.10, 1 hit |
InterProi | View protein in InterPro IPR008183, Aldose_1/G6P_1-epimerase IPR025532, G6P_1-epimerase IPR011013, Gal_mutarotase_sf_dom IPR014718, GH-type_carb-bd |
Pfami | View protein in Pfam PF01263, Aldose_epim, 1 hit |
PIRSFi | PIRSF016020, PHexose_mutarotase, 1 hit |
SUPFAMi | SSF74650, SSF74650, 1 hit |
i Sequence
Sequence statusi: Complete.
P39173-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MIKKIFALPV IEQISPVLSR RKLDELDLIV VDHPQVKASF ALQGAHLLSW
60 70 80 90 100
KPAGEEEVLW LSNNTPFKNG VAIRGGVPVC WPWFGPAAQQ GLPAHGFARN
110 120 130 140 150
LPWTLKSHHE DADGVALTFE LTQSEETKKF WPHDFTLLAH FRVGKTCEID
160 170 180 190 200
LESHGEFETT SALHTYFNVG DIAKVSVSGL GDRFIDKVND AKENVLTDGI
210 220 230 240 250
QTFPDRTDRV YLNPQDCSVI NDEALNRIIA VGHQHHLNVV GWNPGPALSI
260 270 280 290
SMGDMPDDGY KTFVCVETAY ASETQKVTKE KPAHLAQSIR VAKR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC74850.2 AP009048 Genomic DNA Translation: BAA15577.1 |
PIRi | D64938 |
RefSeqi | NP_416294.4, NC_000913.3 WP_001335909.1, NZ_SSZK01000001.1 |
Genome annotation databases
EnsemblBacteriai | AAC74850; AAC74850; b1780 BAA15577; BAA15577; BAA15577 |
GeneIDi | 57731175 946572 |
KEGGi | ecj:JW1769 eco:b1780 |
PATRICi | fig|511145.12.peg.1853 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC74850.2 AP009048 Genomic DNA Translation: BAA15577.1 |
PIRi | D64938 |
RefSeqi | NP_416294.4, NC_000913.3 WP_001335909.1, NZ_SSZK01000001.1 |
3D structure databases
SMRi | P39173 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4260309, 34 interactors |
IntActi | P39173, 2 interactors |
STRINGi | 511145.b1780 |
Proteomic databases
jPOSTi | P39173 |
PaxDbi | P39173 |
PRIDEi | P39173 |
Genome annotation databases
EnsemblBacteriai | AAC74850; AAC74850; b1780 BAA15577; BAA15577; BAA15577 |
GeneIDi | 57731175 946572 |
KEGGi | ecj:JW1769 eco:b1780 |
PATRICi | fig|511145.12.peg.1853 |
Organism-specific databases
EchoBASEi | EB2544 |
Phylogenomic databases
eggNOGi | COG0676, Bacteria |
HOGENOMi | CLU_048345_4_1_6 |
InParanoidi | P39173 |
PhylomeDBi | P39173 |
Enzyme and pathway databases
BioCyci | EcoCyc:G6966-MONOMER |
Miscellaneous databases
PROi | PR:P39173 |
Family and domain databases
CDDi | cd09020, D-hex-6-P-epi_like, 1 hit |
Gene3Di | 2.70.98.10, 1 hit |
InterProi | View protein in InterPro IPR008183, Aldose_1/G6P_1-epimerase IPR025532, G6P_1-epimerase IPR011013, Gal_mutarotase_sf_dom IPR014718, GH-type_carb-bd |
Pfami | View protein in Pfam PF01263, Aldose_epim, 1 hit |
PIRSFi | PIRSF016020, PHexose_mutarotase, 1 hit |
SUPFAMi | SSF74650, SSF74650, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | YEAD_ECOLI | |
Accessioni | P39173Primary (citable) accession number: P39173 Secondary accession number(s): P76233, P76913 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1995 |
Last sequence update: | November 1, 1997 | |
Last modified: | February 10, 2021 | |
This is version 137 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Direct protein sequencing, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families