UniProtKB - P39161 (UXUR_ECOLI)
Protein
Uxu operon transcriptional regulator
Gene
uxuR
Organism
Escherichia coli (strain K12)
Status
Functioni
Repressor for the uxuRBA operon.
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 36 – 55 | H-T-H motifPROSITE-ProRule annotationAdd BLAST | 20 |
GO - Molecular functioni
- DNA binding Source: UniProtKB-KW
- DNA-binding transcription factor activity Source: InterPro
GO - Biological processi
- transcription, DNA-templated Source: EcoCyc
Keywordsi
Molecular function | DNA-binding, Repressor |
Biological process | Transcription, Transcription regulation |
Enzyme and pathway databases
BioCyci | EcoCyc:EG20249-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Uxu operon transcriptional regulator |
Gene namesi | Name:uxuR Ordered Locus Names:b4324, JW4287 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000050670 | 1 – 257 | Uxu operon transcriptional regulatorAdd BLAST | 257 |
Proteomic databases
jPOSTi | P39161 |
PaxDbi | P39161 |
PRIDEi | P39161 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4261007, 10 interactors |
DIPi | DIP-11110N |
IntActi | P39161, 2 interactors |
STRINGi | 511145.b4324 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 8 – 76 | HTH gntR-typePROSITE-ProRule annotationAdd BLAST | 69 |
Phylogenomic databases
eggNOGi | COG2186, Bacteria |
HOGENOMi | CLU_017584_9_5_6 |
InParanoidi | P39161 |
PhylomeDBi | P39161 |
Family and domain databases
CDDi | cd07377, WHTH_GntR, 1 hit |
Gene3Di | 1.10.10.10, 1 hit 1.20.120.530, 1 hit |
InterProi | View protein in InterPro IPR011711, GntR_C IPR008920, TF_FadR/GntR_C IPR000524, Tscrpt_reg_HTH_GntR IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
Pfami | View protein in Pfam PF07729, FCD, 1 hit PF00392, GntR, 1 hit |
PRINTSi | PR00035, HTHGNTR |
SMARTi | View protein in SMART SM00895, FCD, 1 hit SM00345, HTH_GNTR, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit SSF48008, SSF48008, 1 hit |
PROSITEi | View protein in PROSITE PS50949, HTH_GNTR, 1 hit |
i Sequence
Sequence statusi: Complete.
P39161-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKSATSAQRP YQEVGAMIRD LIIKTPYNPG ERLPPEREIA EMLDVTRTVV
60 70 80 90 100
REALIMLEIK GLVEVRRGAG IYVLDNSGSQ NTDSPDANVC NDAGPFELLQ
110 120 130 140 150
ARQLLESNIA EFAALQATRE DIVKMRQALQ LEERELASSA PGSSESGDMQ
160 170 180 190 200
FHLAIAEATH NSMLVELFRQ SWQWRENNPM WIQLHSHLDD SLYRKEWLGD
210 220 230 240 250
HKQILAALIK KDARAAKLAM WQHLENVKQR LLEFSNVDDI YFDGYLFDSW
PLDKVDA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D13329 Genomic DNA Translation: BAA02592.1 U14003 Genomic DNA Translation: AAA97220.1 U00096 Genomic DNA Translation: AAC77280.1 AP009048 Genomic DNA Translation: BAE78317.1 |
PIRi | S56549 |
RefSeqi | NP_418744.1, NC_000913.3 WP_000833679.1, NZ_SSUV01000012.1 |
Genome annotation databases
EnsemblBacteriai | AAC77280; AAC77280; b4324 BAE78317; BAE78317; BAE78317 |
GeneIDi | 948849 |
KEGGi | ecj:JW4287 eco:b4324 |
PATRICi | fig|511145.12.peg.4466 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D13329 Genomic DNA Translation: BAA02592.1 U14003 Genomic DNA Translation: AAA97220.1 U00096 Genomic DNA Translation: AAC77280.1 AP009048 Genomic DNA Translation: BAE78317.1 |
PIRi | S56549 |
RefSeqi | NP_418744.1, NC_000913.3 WP_000833679.1, NZ_SSUV01000012.1 |
3D structure databases
SMRi | P39161 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4261007, 10 interactors |
DIPi | DIP-11110N |
IntActi | P39161, 2 interactors |
STRINGi | 511145.b4324 |
Proteomic databases
jPOSTi | P39161 |
PaxDbi | P39161 |
PRIDEi | P39161 |
Genome annotation databases
EnsemblBacteriai | AAC77280; AAC77280; b4324 BAE78317; BAE78317; BAE78317 |
GeneIDi | 948849 |
KEGGi | ecj:JW4287 eco:b4324 |
PATRICi | fig|511145.12.peg.4466 |
Organism-specific databases
EchoBASEi | EB4151 |
Phylogenomic databases
eggNOGi | COG2186, Bacteria |
HOGENOMi | CLU_017584_9_5_6 |
InParanoidi | P39161 |
PhylomeDBi | P39161 |
Enzyme and pathway databases
BioCyci | EcoCyc:EG20249-MONOMER |
Miscellaneous databases
PROi | PR:P39161 |
Family and domain databases
CDDi | cd07377, WHTH_GntR, 1 hit |
Gene3Di | 1.10.10.10, 1 hit 1.20.120.530, 1 hit |
InterProi | View protein in InterPro IPR011711, GntR_C IPR008920, TF_FadR/GntR_C IPR000524, Tscrpt_reg_HTH_GntR IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
Pfami | View protein in Pfam PF07729, FCD, 1 hit PF00392, GntR, 1 hit |
PRINTSi | PR00035, HTHGNTR |
SMARTi | View protein in SMART SM00895, FCD, 1 hit SM00345, HTH_GNTR, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit SSF48008, SSF48008, 1 hit |
PROSITEi | View protein in PROSITE PS50949, HTH_GNTR, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | UXUR_ECOLI | |
Accessioni | P39161Primary (citable) accession number: P39161 Secondary accession number(s): Q2M5Y9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1995 |
Last sequence update: | February 1, 1995 | |
Last modified: | December 2, 2020 | |
This is version 144 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |