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Entry version 197 (13 Feb 2019)
Sequence version 2 (30 May 2000)
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Protein

Metal resistance protein YCF1

Gene

YCF1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Cooperates for the ATP-dependent vacuolar transport of bilirubin and glutathione conjugates.2 Publications

Miscellaneous

Present with 396 molecules/cell in log phase SD medium.1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi663 – 670ATP 1PROSITE-ProRule annotation8
Nucleotide bindingi1306 – 1313ATP 2PROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • ATPase activity, coupled to transmembrane movement of substances Source: GO_Central
  • ATP binding Source: UniProtKB-KW
  • bilirubin transmembrane transporter activity Source: SGD
  • glutathione S-conjugate-exporting ATPase activity Source: SGD

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTranslocase
Biological processCadmium resistance, Transport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
MetaCyc:G3O-29733-MONOMER
YEAST:G3O-29733-MONOMER

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-SCE-114608 Platelet degranulation
R-SCE-196741 Cobalamin (Cbl, vitamin B12) transport and metabolism
R-SCE-2142691 Synthesis of Leukotrienes (LT) and Eoxins (EX)
R-SCE-2142850 Hyaluronan biosynthesis and export
R-SCE-382556 ABC-family proteins mediated transport

Protein family/group databases

Transport Classification Database

More...
TCDBi
3.A.1.208.11 the atp-binding cassette (abc) superfamily

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Metal resistance protein YCF1
Alternative name(s):
ABC-type Cd(2+) transporter (EC:7.2.2.21 Publication)
ABC-type glutathione-S-conjugate transporter (EC:7.6.2.31 Publication)
Yeast cadmium factor 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:YCF1
Ordered Locus Names:YDR135C
ORF Names:YD9302.11C
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559292 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome IV

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
FungiDB:YDR135C

Saccharomyces Genome Database

More...
SGDi
S000002542 YCF1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 32VacuolarSequence analysisAdd BLAST32
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei33 – 53Helical; Name=1PROSITE-ProRule annotationAdd BLAST21
Topological domaini54 – 73CytoplasmicSequence analysisAdd BLAST20
Transmembranei74 – 94Helical; Name=2PROSITE-ProRule annotationAdd BLAST21
Topological domaini95 – 99VacuolarSequence analysis5
Transmembranei100 – 120Helical; Name=3PROSITE-ProRule annotationAdd BLAST21
Topological domaini121 – 130CytoplasmicSequence analysis10
Transmembranei131 – 151Helical; Name=4PROSITE-ProRule annotationAdd BLAST21
Topological domaini152 – 169VacuolarSequence analysisAdd BLAST18
Transmembranei170 – 190Helical; Name=5PROSITE-ProRule annotationAdd BLAST21
Topological domaini191 – 278CytoplasmicSequence analysisAdd BLAST88
Transmembranei279 – 299Helical; Name=6PROSITE-ProRule annotationAdd BLAST21
Topological domaini300 – 345VacuolarSequence analysisAdd BLAST46
Transmembranei346 – 366Helical; Name=7PROSITE-ProRule annotationAdd BLAST21
Topological domaini367 – 422CytoplasmicSequence analysisAdd BLAST56
Transmembranei423 – 443Helical; Name=8PROSITE-ProRule annotationAdd BLAST21
Topological domaini444 – 446VacuolarSequence analysis3
Transmembranei447 – 467Helical; Name=9PROSITE-ProRule annotationAdd BLAST21
Topological domaini468 – 530CytoplasmicSequence analysisAdd BLAST63
Transmembranei531 – 551Helical; Name=10PROSITE-ProRule annotationAdd BLAST21
Topological domaini552 – 572VacuolarSequence analysisAdd BLAST21
Transmembranei573 – 593Helical; Name=11PROSITE-ProRule annotationAdd BLAST21
Topological domaini594 – 943CytoplasmicSequence analysisAdd BLAST350
Transmembranei944 – 964Helical; Name=12PROSITE-ProRule annotationAdd BLAST21
Topological domaini965 – 1001VacuolarSequence analysisAdd BLAST37
Transmembranei1002 – 1023Helical; Name=13PROSITE-ProRule annotationAdd BLAST22
Topological domaini1024 – 1066CytoplasmicSequence analysisAdd BLAST43
Transmembranei1067 – 1087Helical; Name=14PROSITE-ProRule annotationAdd BLAST21
Topological domaini1088VacuolarSequence analysis1
Transmembranei1089 – 1109Helical; Name=15PROSITE-ProRule annotationAdd BLAST21
Topological domaini1110 – 1180CytoplasmicSequence analysisAdd BLAST71
Transmembranei1181 – 1201Helical; Name=16PROSITE-ProRule annotationAdd BLAST21
Topological domaini1202 – 1205VacuolarSequence analysis4
Transmembranei1206 – 1226Helical; Name=17PROSITE-ProRule annotationAdd BLAST21
Topological domaini1227 – 1515CytoplasmicSequence analysisAdd BLAST289

Keywords - Cellular componenti

Membrane, Vacuole

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi713Missing : Loss of function. 1
Mutagenesisi908S → A: Loss of function. 1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000934491 – 1515Metal resistance protein YCF1Add BLAST1515

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei251PhosphoserineCombined sources1
Modified residuei873PhosphoserineCombined sources1
Modified residuei903PhosphoserineCombined sources1
Modified residuei908PhosphoserineCombined sources1
Modified residuei911PhosphothreonineCombined sources1
Modified residuei914PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P39109

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P39109

PRoteomics IDEntifications database

More...
PRIDEi
P39109

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P39109

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
32190, 109 interactors

Database of interacting proteins

More...
DIPi
DIP-2612N

Protein interaction database and analysis system

More...
IntActi
P39109, 33 interactors

Molecular INTeraction database

More...
MINTi
P39109

STRING: functional protein association networks

More...
STRINGi
4932.YDR135C

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
P39109

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P39109

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini287 – 590ABC transmembrane type-1 1PROSITE-ProRule annotationAdd BLAST304
Domaini626 – 853ABC transporter 1PROSITE-ProRule annotationAdd BLAST228
Domaini951 – 1235ABC transmembrane type-1 2PROSITE-ProRule annotationAdd BLAST285
Domaini1272 – 1507ABC transporter 2PROSITE-ProRule annotationAdd BLAST236

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000166156

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P39109

KEGG Orthology (KO)

More...
KOi
K05665

Identification of Orthologs from Complete Genome Data

More...
OMAi
NEWRVDA

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.1560.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR027417 P-loop_NTPase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00664 ABC_membrane, 2 hits
PF00005 ABC_tran, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382 AAA, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 2 hits
SSF90123 SSF90123, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50929 ABC_TM1F, 2 hits
PS00211 ABC_TRANSPORTER_1, 2 hits
PS50893 ABC_TRANSPORTER_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P39109-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAGNLVSWAC KLCRSPEGFG PISFYGDFTQ CFIDGVILNL SAIFMITFGI
60 70 80 90 100
RDLVNLCKKK HSGIKYRRNW IIVSRMALVL LEIAFVSLAS LNISKEEAEN
110 120 130 140 150
FTIVSQYAST MLSLFVALAL HWIEYDRSVV ANTVLLFYWL FETFGNFAKL
160 170 180 190 200
INILIRHTYE GIWYSGQTGF ILTLFQVITC ASILLLEALP KKPLMPHQHI
210 220 230 240 250
HQTLTRRKPN PYDSANIFSR ITFSWMSGLM KTGYEKYLVE ADLYKLPRNF
260 270 280 290 300
SSEELSQKLE KNWENELKQK SNPSLSWAIC RTFGSKMLLA AFFKAIHDVL
310 320 330 340 350
AFTQPQLLRI LIKFVTDYNS ERQDDHSSLQ GFENNHPQKL PIVRGFLIAF
360 370 380 390 400
AMFLVGFTQT SVLHQYFLNV FNTGMYIKSA LTALIYQKSL VLSNEASGLS
410 420 430 440 450
STGDIVNLMS VDVQKLQDLT QWLNLIWSGP FQIIICLYSL YKLLGNSMWV
460 470 480 490 500
GVIILVIMMP LNSFLMRIQK KLQKSQMKYK DERTRVISEI LNNIKSLKLY
510 520 530 540 550
AWEKPYREKL EEVRNNKELK NLTKLGCYMA VTSFQFNIVP FLVSCCTFAV
560 570 580 590 600
FVYTEDRALT TDLVFPALTL FNLLSFPLMI IPMVLNSFIE ASVSIGRLFT
610 620 630 640 650
FFTNEELQPD SVQRLPKVKN IGDVAINIGD DATFLWQRKP EYKVALKNIN
660 670 680 690 700
FQAKKGNLTC IVGKVGSGKT ALLSCMLGDL FRVKGFATVH GSVAYVSQVP
710 720 730 740 750
WIMNGTVKEN ILFGHRYDAE FYEKTIKACA LTIDLAILMD GDKTLVGEKG
760 770 780 790 800
ISLSGGQKAR LSLARAVYAR ADTYLLDDPL AAVDEHVARH LIEHVLGPNG
810 820 830 840 850
LLHTKTKVLA TNKVSALSIA DSIALLDNGE ITQQGTYDEI TKDADSPLWK
860 870 880 890 900
LLNNYGKKNN GKSNEFGDSS ESSVRESSIP VEGELEQLQK LNDLDFGNSD
910 920 930 940 950
AISLRRASDA TLGSIDFGDD ENIAKREHRE QGKVKWNIYL EYAKACNPKS
960 970 980 990 1000
VCVFILFIVI SMFLSVMGNV WLKHWSEVNS RYGSNPNAAR YLAIYFALGI
1010 1020 1030 1040 1050
GSALATLIQT IVLWVFCTIH ASKYLHNLMT NSVLRAPMTF FETTPIGRIL
1060 1070 1080 1090 1100
NRFSNDIYKV DALLGRTFSQ FFVNAVKVTF TITVICATTW QFIFIIIPLS
1110 1120 1130 1140 1150
VFYIYYQQYY LRTSRELRRL DSITRSPIYS HFQETLGGLA TVRGYSQQKR
1160 1170 1180 1190 1200
FSHINQCRID NNMSAFYPSI NANRWLAYRL ELIGSIIILG AATLSVFRLK
1210 1220 1230 1240 1250
QGTLTAGMVG LSLSYALQIT QTLNWIVRMT VEVETNIVSV ERIKEYADLK
1260 1270 1280 1290 1300
SEAPLIVEGH RPPKEWPSQG DIKFNNYSTR YRPELDLVLK HINIHIKPNE
1310 1320 1330 1340 1350
KVGIVGRTGA GKSSLTLALF RMIEASEGNI VIDNIAINEI GLYDLRHKLS
1360 1370 1380 1390 1400
IIPQDSQVFE GTVRENIDPI NQYTDEAIWR ALELSHLKEH VLSMSNDGLD
1410 1420 1430 1440 1450
AQLTEGGGNL SVGQRQLLCL ARAMLVPSKI LVLDEATAAV DVETDKVVQE
1460 1470 1480 1490 1500
TIRTAFKDRT ILTIAHRLNT IMDSDRIIVL DNGKVAEFDS PGQLLSDNKS
1510
LFYSLCMEAG LVNEN
Length:1,515
Mass (Da):171,121
Last modified:May 30, 2000 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i30F92FDDBAF60431
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti680L → R in AAA50353 (PubMed:7521334).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
L35237 Genomic DNA Translation: AAA50353.1
Z48179 Genomic DNA Translation: CAA88217.1
BK006938 Genomic DNA Translation: DAA11979.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S51863

NCBI Reference Sequences

More...
RefSeqi
NP_010419.3, NM_001180442.3

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
YDR135C_mRNA; YDR135C_mRNA; YDR135C

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
851713

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
sce:YDR135C

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L35237 Genomic DNA Translation: AAA50353.1
Z48179 Genomic DNA Translation: CAA88217.1
BK006938 Genomic DNA Translation: DAA11979.1
PIRiS51863
RefSeqiNP_010419.3, NM_001180442.3

3D structure databases

ProteinModelPortaliP39109
SMRiP39109
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi32190, 109 interactors
DIPiDIP-2612N
IntActiP39109, 33 interactors
MINTiP39109
STRINGi4932.YDR135C

Protein family/group databases

TCDBi3.A.1.208.11 the atp-binding cassette (abc) superfamily

PTM databases

iPTMnetiP39109

Proteomic databases

MaxQBiP39109
PaxDbiP39109
PRIDEiP39109

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYDR135C_mRNA; YDR135C_mRNA; YDR135C
GeneIDi851713
KEGGisce:YDR135C

Organism-specific databases

EuPathDBiFungiDB:YDR135C
SGDiS000002542 YCF1

Phylogenomic databases

GeneTreeiENSGT00940000166156
InParanoidiP39109
KOiK05665
OMAiNEWRVDA

Enzyme and pathway databases

BioCyciMetaCyc:G3O-29733-MONOMER
YEAST:G3O-29733-MONOMER
ReactomeiR-SCE-114608 Platelet degranulation
R-SCE-196741 Cobalamin (Cbl, vitamin B12) transport and metabolism
R-SCE-2142691 Synthesis of Leukotrienes (LT) and Eoxins (EX)
R-SCE-2142850 Hyaluronan biosynthesis and export
R-SCE-382556 ABC-family proteins mediated transport

Miscellaneous databases

Protein Ontology

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PROi
PR:P39109

Family and domain databases

Gene3Di1.20.1560.10, 2 hits
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00664 ABC_membrane, 2 hits
PF00005 ABC_tran, 2 hits
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SUPFAMiSSF52540 SSF52540, 2 hits
SSF90123 SSF90123, 2 hits
PROSITEiView protein in PROSITE
PS50929 ABC_TM1F, 2 hits
PS00211 ABC_TRANSPORTER_1, 2 hits
PS50893 ABC_TRANSPORTER_2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYCFI_YEAST
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P39109
Secondary accession number(s): D6VSB9, Q03905
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: May 30, 2000
Last modified: February 13, 2019
This is version 197 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast chromosome IV
    Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
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