Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 174 (18 Sep 2019)
Sequence version 1 (01 Feb 1995)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Casein kinase II subunit beta'

Gene

CKB2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays a complex role in regulating the basal catalytic activity of the alpha subunit.By similarity

Miscellaneous

Present with 7160 molecules/cell in log phase SD medium.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
YEAST:G3O-33585-MONOMER

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-SCE-6798695 Neutrophil degranulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Casein kinase II subunit beta'
Short name:
CK II beta'
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CKB2
Ordered Locus Names:YOR039W
ORF Names:OR26.32
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559292 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome XV

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
FungiDB:YOR039W

Saccharomyces Genome Database

More...
SGDi
S000005565 CKB2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000682581 – 258Casein kinase II subunit beta'Add BLAST258

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylated by alpha subunit.By similarity
The N-terminus is blocked.

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P38930

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P38930

PRoteomics IDEntifications database

More...
PRIDEi
P38930

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P38930

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Tetramer composed of an alpha subunit, an alpha' subunit, one beta subunit and one beta' subunit.

Interacts with FACT subunits POB3 and SPT16.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
34441, 509 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-581 Protein kinase CK2 variant 1
CPX-769 Protein kinase CK2 variant 2
CPX-770 Protein kinase CK2 variant 3
CPX-771 UTP-C complex variant 2
CPX-772 UTP-C complex variant 1
CPX-773 UTP-C complex variant 3
CPX-774 CURI complex variant 1
CPX-775 CURI complex variant 2
CPX-776 CURI complex variant 3

Database of interacting proteins

More...
DIPi
DIP-262N

Protein interaction database and analysis system

More...
IntActi
P38930, 46 interactors

Molecular INTeraction database

More...
MINTi
P38930

STRING: functional protein association networks

More...
STRINGi
4932.YOR039W

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P38930

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000039270

KEGG Orthology (KO)

More...
KOi
K03115

Identification of Orthologs from Complete Genome Data

More...
OMAi
CPRVLCQ

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.1820.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016149 Casein_kin_II_reg-sub_N
IPR035991 Casein_kinase_II_beta-like
IPR000704 Casein_kinase_II_reg-sub

The PANTHER Classification System

More...
PANTHERi
PTHR11740 PTHR11740, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01214 CK_II_beta, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00472 CASNKINASEII

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01085 CK_II_beta, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57798 SSF57798, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01101 CK2_BETA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P38930-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGSRSENVGT VTREGSRVEQ DDVLMDDDSD SSEYVDMWID LFLGRKGHEY
60 70 80 90 100
FCDVDPEYIT DRFNLMNLQK TVSKFSYVVQ YIVDDLDDSI LENMTHARLE
110 120 130 140 150
QLESDSRKLY GLIHARYIIT IKGLQKMYAK YKEADFGRCP RVYCNLQQLL
160 170 180 190 200
PVGLHDIPGI DCVKLYCPSC EDLYIPKSSR HSSIDGAYFG TSFPGMFLQA
210 220 230 240 250
FPDMVPKHPT KRYVPKIFGF ELHKQAQLTR WQELQRLKLV EKLESKDVDL

TKSGGFKT
Length:258
Mass (Da):29,842
Last modified:February 1, 1995 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD6060CB3D70B19A4
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U08849 Genomic DNA Translation: AAA21656.1
X87331 Genomic DNA Translation: CAA60758.1
Z74947 Genomic DNA Translation: CAA99229.1
AY692981 Genomic DNA Translation: AAT93000.1
X82893 Genomic DNA Translation: CAA58064.1
BK006948 Genomic DNA Translation: DAA10822.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A54907

NCBI Reference Sequences

More...
RefSeqi
NP_014682.1, NM_001183458.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
YOR039W_mRNA; YOR039W; YOR039W

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
854204

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
sce:YOR039W

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U08849 Genomic DNA Translation: AAA21656.1
X87331 Genomic DNA Translation: CAA60758.1
Z74947 Genomic DNA Translation: CAA99229.1
AY692981 Genomic DNA Translation: AAT93000.1
X82893 Genomic DNA Translation: CAA58064.1
BK006948 Genomic DNA Translation: DAA10822.1
PIRiA54907
RefSeqiNP_014682.1, NM_001183458.1

3D structure databases

SMRiP38930
ModBaseiSearch...

Protein-protein interaction databases

BioGridi34441, 509 interactors
ComplexPortaliCPX-581 Protein kinase CK2 variant 1
CPX-769 Protein kinase CK2 variant 2
CPX-770 Protein kinase CK2 variant 3
CPX-771 UTP-C complex variant 2
CPX-772 UTP-C complex variant 1
CPX-773 UTP-C complex variant 3
CPX-774 CURI complex variant 1
CPX-775 CURI complex variant 2
CPX-776 CURI complex variant 3
DIPiDIP-262N
IntActiP38930, 46 interactors
MINTiP38930
STRINGi4932.YOR039W

PTM databases

iPTMnetiP38930

Proteomic databases

MaxQBiP38930
PaxDbiP38930
PRIDEiP38930

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYOR039W_mRNA; YOR039W; YOR039W
GeneIDi854204
KEGGisce:YOR039W

Organism-specific databases

EuPathDBiFungiDB:YOR039W
SGDiS000005565 CKB2

Phylogenomic databases

HOGENOMiHOG000039270
KOiK03115
OMAiCPRVLCQ

Enzyme and pathway databases

BioCyciYEAST:G3O-33585-MONOMER
ReactomeiR-SCE-6798695 Neutrophil degranulation

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P38930

Family and domain databases

Gene3Di1.10.1820.10, 1 hit
InterProiView protein in InterPro
IPR016149 Casein_kin_II_reg-sub_N
IPR035991 Casein_kinase_II_beta-like
IPR000704 Casein_kinase_II_reg-sub
PANTHERiPTHR11740 PTHR11740, 1 hit
PfamiView protein in Pfam
PF01214 CK_II_beta, 1 hit
PRINTSiPR00472 CASNKINASEII
SMARTiView protein in SMART
SM01085 CK_II_beta, 1 hit
SUPFAMiSSF57798 SSF57798, 1 hit
PROSITEiView protein in PROSITE
PS01101 CK2_BETA, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCSK2C_YEAST
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P38930
Secondary accession number(s): D6W2A6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: September 18, 2019
This is version 174 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome XV
    Yeast (Saccharomyces cerevisiae) chromosome XV: entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again