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UniProtKB - P38858 (SOL3_YEAST)
Protein
6-phosphogluconolactonase 3
Gene
SOL3
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
1 PublicationMiscellaneous
Present with 3420 molecules/cell in log phase SD medium.1 Publication
Catalytic activityi
- EC:3.1.1.311 Publication
: pentose phosphate pathway Pathwayi
This protein is involved in step 2 of the subpathway that synthesizes D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage). This subpathway is part of the pathway pentose phosphate pathway, which is itself part of Carbohydrate degradation.View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage), the pathway pentose phosphate pathway and in Carbohydrate degradation.
GO - Molecular functioni
- 6-phosphogluconolactonase activity Source: SGD
GO - Biological processi
- carbohydrate metabolic process Source: InterPro
- pentose-phosphate shunt, oxidative branch Source: GO_Central
Keywordsi
Molecular function | Hydrolase |
Enzyme and pathway databases
Reactomei | R-SCE-71336, Pentose phosphate pathway |
UniPathwayi | UPA00115;UER00409 |
Names & Taxonomyi
Protein namesi | Recommended name: 6-phosphogluconolactonase 31 Publication (EC:3.1.1.311 Publication)Short name: 6PGL1 Publication |
Gene namesi | Name:SOL31 Publication Ordered Locus Names:YHR163W |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
SGDi | S000001206, SOL3 |
VEuPathDBi | FungiDB:YHR163W |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000090084 | 1 – 249 | 6-phosphogluconolactonase 3Add BLAST | 249 |
Proteomic databases
MaxQBi | P38858 |
PaxDbi | P38858 |
PRIDEi | P38858 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 36597, 91 interactors |
DIPi | DIP-5625N |
IntActi | P38858, 1 interactor |
STRINGi | 4932.YHR163W |
Miscellaneous databases
RNActi | P38858, protein |
Family & Domainsi
Sequence similaritiesi
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.Curated
Phylogenomic databases
eggNOGi | KOG3147, Eukaryota |
GeneTreei | ENSGT00550000075110 |
HOGENOMi | CLU_053947_0_1_1 |
InParanoidi | P38858 |
OMAi | SKQPIMH |
Family and domain databases
CDDi | cd01400, 6PGL, 1 hit |
InterProi | View protein in InterPro IPR005900, 6-phosphogluconolactonase_DevB IPR006148, Glc/Gal-6P_isomerase IPR037171, NagB/RpiA_transferase-like IPR039104, PGLS |
PANTHERi | PTHR11054, PTHR11054, 1 hit |
Pfami | View protein in Pfam PF01182, Glucosamine_iso, 1 hit |
SUPFAMi | SSF100950, SSF100950, 1 hit |
TIGRFAMsi | TIGR01198, pgl, 1 hit |
i Sequence
Sequence statusi: Complete.
P38858-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MVTVGVFSER ASLTHQLGEF IVKKQDEALQ KKSDFKVSVS GGSLIDALYE
60 70 80 90 100
SLVADESLSS RVQWSKWQIY FSDERIVPLT DADSNYGAFK RAVLDKLPST
110 120 130 140 150
SQPNVYPMDE SLIGSDAESN NKIAAEYERI VPQVLDLVLL GCGPDGHTCS
160 170 180 190 200
LFPGETHRYL LNETTKRVAW CHDSPKPPSD RITFTLPVLK DAKALCFVAE
210 220 230 240
GSSKQNIMHE IFDLKNDQLP TALVNKLFGE KTSWFVNEEA FGKVQTKTF
Sequence cautioni
The sequence AAB49323 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAB68008 differs from that shown. Reason: Erroneous initiation.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U46560 Genomic DNA Translation: AAB49323.1 Different initiation. U00027 Genomic DNA Translation: AAB68008.1 Different initiation. BK006934 Genomic DNA Translation: DAA06856.1 |
PIRi | S48903 |
RefSeqi | NP_012033.2, NM_001179294.1 |
Genome annotation databases
EnsemblFungii | YHR163W_mRNA; YHR163W; YHR163W |
GeneIDi | 856568 |
KEGGi | sce:YHR163W |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U46560 Genomic DNA Translation: AAB49323.1 Different initiation. U00027 Genomic DNA Translation: AAB68008.1 Different initiation. BK006934 Genomic DNA Translation: DAA06856.1 |
PIRi | S48903 |
RefSeqi | NP_012033.2, NM_001179294.1 |
3D structure databases
SMRi | P38858 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 36597, 91 interactors |
DIPi | DIP-5625N |
IntActi | P38858, 1 interactor |
STRINGi | 4932.YHR163W |
Proteomic databases
MaxQBi | P38858 |
PaxDbi | P38858 |
PRIDEi | P38858 |
Genome annotation databases
EnsemblFungii | YHR163W_mRNA; YHR163W; YHR163W |
GeneIDi | 856568 |
KEGGi | sce:YHR163W |
Organism-specific databases
SGDi | S000001206, SOL3 |
VEuPathDBi | FungiDB:YHR163W |
Phylogenomic databases
eggNOGi | KOG3147, Eukaryota |
GeneTreei | ENSGT00550000075110 |
HOGENOMi | CLU_053947_0_1_1 |
InParanoidi | P38858 |
OMAi | SKQPIMH |
Enzyme and pathway databases
UniPathwayi | UPA00115;UER00409 |
Reactomei | R-SCE-71336, Pentose phosphate pathway |
Miscellaneous databases
PROi | PR:P38858 |
RNActi | P38858, protein |
Family and domain databases
CDDi | cd01400, 6PGL, 1 hit |
InterProi | View protein in InterPro IPR005900, 6-phosphogluconolactonase_DevB IPR006148, Glc/Gal-6P_isomerase IPR037171, NagB/RpiA_transferase-like IPR039104, PGLS |
PANTHERi | PTHR11054, PTHR11054, 1 hit |
Pfami | View protein in Pfam PF01182, Glucosamine_iso, 1 hit |
SUPFAMi | SSF100950, SSF100950, 1 hit |
TIGRFAMsi | TIGR01198, pgl, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | SOL3_YEAST | |
Accessioni | P38858Primary (citable) accession number: P38858 Secondary accession number(s): D3DLB2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1995 |
Last sequence update: | June 16, 2009 | |
Last modified: | February 23, 2022 | |
This is version 160 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD - Yeast chromosome VIII
Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names - PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families