UniProtKB - P38842 (YHU0_YEAST)
Protein
UPF0641 membrane protein YHR140W
Gene
YHR140W
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
Caution
It is uncertain whether Met-1 or Met-2 is the initiator.Curated
Names & Taxonomyi
Protein namesi | Recommended name: UPF0641 membrane protein YHR140W |
Gene namesi | Ordered Locus Names:YHR140W |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
SGDi | S000001182, YHR140W |
VEuPathDBi | FungiDB:YHR140W |
Subcellular locationi
Endoplasmic reticulum
- Endoplasmic reticulum membrane 1 Publication; Multi-pass membrane protein 1 Publication
Endoplasmic reticulum
- endoplasmic reticulum Source: SGD
- endoplasmic reticulum membrane Source: UniProtKB-SubCell
Other locations
- cytoplasm Source: SGD
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 11 | CytoplasmicSequence analysisAdd BLAST | 11 | |
Transmembranei | 12 – 31 | HelicalSequence analysisAdd BLAST | 20 | |
Topological domaini | 32 – 45 | LumenalSequence analysisAdd BLAST | 14 | |
Transmembranei | 46 – 66 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 67 – 99 | CytoplasmicSequence analysisAdd BLAST | 33 | |
Transmembranei | 100 – 120 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 121 – 125 | LumenalSequence analysis | 5 | |
Transmembranei | 126 – 146 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 147 – 162 | CytoplasmicSequence analysisAdd BLAST | 16 | |
Transmembranei | 163 – 183 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 184 – 204 | LumenalSequence analysisAdd BLAST | 21 | |
Transmembranei | 205 – 225 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 226 – 239 | CytoplasmicSequence analysisAdd BLAST | 14 |
Keywords - Cellular componenti
Endoplasmic reticulum, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000202921 | 1 – 239 | UPF0641 membrane protein YHR140WAdd BLAST | 239 |
Proteomic databases
PaxDbi | P38842 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 36573, 90 interactors |
DIPi | DIP-1786N |
IntActi | P38842, 9 interactors |
MINTi | P38842 |
STRINGi | 4932.YHR140W |
Miscellaneous databases
RNActi | P38842, protein |
Family & Domainsi
Sequence similaritiesi
Belongs to the UPF0641 family.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG3989, Eukaryota |
HOGENOMi | CLU_087038_0_0_1 |
InParanoidi | P38842 |
OMAi | VYWCWIE |
Family and domain databases
InterProi | View protein in InterPro IPR006838, Far-17a_AIG1 |
PANTHERi | PTHR10989, PTHR10989, 1 hit |
Pfami | View protein in Pfam PF04750, Far-17a_AIG1, 1 hit |
i Sequence
Sequence statusi: Complete.
P38842-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MMSCLVPTRF TLTLNTACLL TSTWGFVRAT SVVLPPSLSK AGHKQFLTII
60 70 80 90 100
SIIATIINNA VNISNYYIQR NNKMNLETKK KSDFISRHVT LPVSLVLESI
110 120 130 140 150
VATVYWPLRL FFVNLIMHGV ESTAKTPFPM TVDMAIHLYP ILYLLADHYL
160 170 180 190 200
SGSGTKFKLS NKHAWLIVTS LAFSYFQYLA FLIDAGQGQA YPYPFLDVNE
210 220 230
PYKSIIFVVV ATITWAYYVF YQKFPPKYIK KSAKKGDKN
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U10398 Genomic DNA Translation: AAB68402.1 AY692727 Genomic DNA Translation: AAT92746.1 BK006934 Genomic DNA Translation: DAA06833.1 |
PIRi | S48984 |
RefSeqi | NP_012009.1, NM_001179270.1 |
Genome annotation databases
EnsemblFungii | YHR140W_mRNA; YHR140W; YHR140W |
GeneIDi | 856543 |
KEGGi | sce:YHR140W |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U10398 Genomic DNA Translation: AAB68402.1 AY692727 Genomic DNA Translation: AAT92746.1 BK006934 Genomic DNA Translation: DAA06833.1 |
PIRi | S48984 |
RefSeqi | NP_012009.1, NM_001179270.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 36573, 90 interactors |
DIPi | DIP-1786N |
IntActi | P38842, 9 interactors |
MINTi | P38842 |
STRINGi | 4932.YHR140W |
Proteomic databases
PaxDbi | P38842 |
Genome annotation databases
EnsemblFungii | YHR140W_mRNA; YHR140W; YHR140W |
GeneIDi | 856543 |
KEGGi | sce:YHR140W |
Organism-specific databases
SGDi | S000001182, YHR140W |
VEuPathDBi | FungiDB:YHR140W |
Phylogenomic databases
eggNOGi | KOG3989, Eukaryota |
HOGENOMi | CLU_087038_0_0_1 |
InParanoidi | P38842 |
OMAi | VYWCWIE |
Miscellaneous databases
PROi | PR:P38842 |
RNActi | P38842, protein |
Family and domain databases
InterProi | View protein in InterPro IPR006838, Far-17a_AIG1 |
PANTHERi | PTHR10989, PTHR10989, 1 hit |
Pfami | View protein in Pfam PF04750, Far-17a_AIG1, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | YHU0_YEAST | |
Accessioni | P38842Primary (citable) accession number: P38842 Secondary accession number(s): D3DL89, Q6B2K3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1995 |
Last sequence update: | April 18, 2006 | |
Last modified: | February 10, 2021 | |
This is version 132 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD - Yeast chromosome VIII
Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names - Uncharacterized protein families (UPF)
List of uncharacterized protein family (UPF) entries - SIMILARITY comments
Index of protein domains and families