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UniProtKB - P38824 (COX23_YEAST)
Protein
Cytochrome c oxidase-assembly factor COX23, mitochondrial
Gene
COX23
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
Required for the assembly of cytochrome c oxidase.
1 PublicationMiscellaneous
Present with 1360 molecules/cell in log phase SD medium.1 Publication
GO - Biological processi
- mitochondrial respiratory chain complex assembly Source: SGD
Names & Taxonomyi
Protein namesi | Recommended name: Cytochrome c oxidase-assembly factor COX23, mitochondrial |
Gene namesi | Name:COX23 Ordered Locus Names:YHR116W |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
SGDi | S000001158, COX23 |
VEuPathDBi | FungiDB:YHR116W |
Subcellular locationi
Mitochondrion
- Mitochondrion intermembrane space 2 Publications
Cytoplasm and Cytosol
- Cytoplasm 1 Publication
Mitochondrion
- mitochondrial intermembrane space Source: UniProtKB-SubCell
- mitochondrion Source: SGD
Other locations
- cytoplasm Source: SGD
Keywords - Cellular componenti
Cytoplasm, MitochondrionPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transit peptidei | 1 – 10 | MitochondrionSequence analysis | 10 | |
ChainiPRO_0000202912 | 11 – 151 | Cytochrome c oxidase-assembly factor COX23, mitochondrialAdd BLAST | 141 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 104 ↔ 135 | PROSITE-ProRule annotation | ||
Disulfide bondi | 114 ↔ 125 | PROSITE-ProRule annotation |
Keywords - PTMi
Disulfide bondProteomic databases
MaxQBi | P38824 |
PaxDbi | P38824 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 36549, 272 interactors |
DIPi | DIP-5306N |
IntActi | P38824, 1 interactor |
MINTi | P38824 |
STRINGi | 4932.YHR116W |
Miscellaneous databases
RNActi | P38824, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 101 – 143 | CHCHPROSITE-ProRule annotationAdd BLAST | 43 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 86 | DisorderedSequence analysisAdd BLAST | 86 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 104 – 114 | Cx9C motif 1PROSITE-ProRule annotationAdd BLAST | 11 | |
Motifi | 125 – 135 | Cx9C motif 2PROSITE-ProRule annotationAdd BLAST | 11 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 7 – 56 | Polar residuesSequence analysisAdd BLAST | 50 |
Sequence similaritiesi
Belongs to the COX23 family.Curated
Keywords - Domaini
Transit peptidePhylogenomic databases
eggNOGi | KOG4618, Eukaryota |
HOGENOMi | CLU_153383_1_0_1 |
InParanoidi | P38824 |
OMAi | DPCQESS |
Family and domain databases
InterProi | View protein in InterPro IPR010625, CHCH IPR009069, Cys_alpha_HP_mot_SF |
Pfami | View protein in Pfam PF06747, CHCH, 1 hit |
SUPFAMi | SSF47072, SSF47072, 1 hit |
PROSITEi | View protein in PROSITE PS51808, CHCH, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P38824-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEKPSPTRRQ TSSLSTISNG MTMTNDNRDT TNTNSGSTSS NNSQPSSSST
60 70 80 90 100
PPAASGPVTD RTKVNYVPKS DDPSSFQYYP DDPENPVNKY KFALKADSQY
110 120 130 140 150
YDPCEESSKL SFQCLERNDY DRSKCQEYFD AYRECKKQWL TARRKNRQQW
E
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00059 Genomic DNA Translation: AAB68866.1 AY692601 Genomic DNA Translation: AAT92620.1 BK006934 Genomic DNA Translation: DAA06810.1 |
PIRi | S48958 |
RefSeqi | NP_011984.1, NM_001179246.1 |
Genome annotation databases
EnsemblFungii | YHR116W_mRNA; YHR116W; YHR116W |
GeneIDi | 856516 |
KEGGi | sce:YHR116W |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00059 Genomic DNA Translation: AAB68866.1 AY692601 Genomic DNA Translation: AAT92620.1 BK006934 Genomic DNA Translation: DAA06810.1 |
PIRi | S48958 |
RefSeqi | NP_011984.1, NM_001179246.1 |
3D structure databases
AlphaFoldDBi | P38824 |
SMRi | P38824 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 36549, 272 interactors |
DIPi | DIP-5306N |
IntActi | P38824, 1 interactor |
MINTi | P38824 |
STRINGi | 4932.YHR116W |
Proteomic databases
MaxQBi | P38824 |
PaxDbi | P38824 |
Genome annotation databases
EnsemblFungii | YHR116W_mRNA; YHR116W; YHR116W |
GeneIDi | 856516 |
KEGGi | sce:YHR116W |
Organism-specific databases
SGDi | S000001158, COX23 |
VEuPathDBi | FungiDB:YHR116W |
Phylogenomic databases
eggNOGi | KOG4618, Eukaryota |
HOGENOMi | CLU_153383_1_0_1 |
InParanoidi | P38824 |
OMAi | DPCQESS |
Miscellaneous databases
PROi | PR:P38824 |
RNActi | P38824, protein |
Family and domain databases
InterProi | View protein in InterPro IPR010625, CHCH IPR009069, Cys_alpha_HP_mot_SF |
Pfami | View protein in Pfam PF06747, CHCH, 1 hit |
SUPFAMi | SSF47072, SSF47072, 1 hit |
PROSITEi | View protein in PROSITE PS51808, CHCH, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | COX23_YEAST | |
Accessioni | P38824Primary (citable) accession number: P38824 Secondary accession number(s): D3DL66 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1995 |
Last sequence update: | February 1, 1995 | |
Last modified: | May 25, 2022 | |
This is version 143 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD - Yeast chromosome VIII
Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names - SIMILARITY comments
Index of protein domains and families