Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Vacuolar ATPase assembly protein VMA22

Gene

VMA22

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Required for V-ATPase activity.

Miscellaneous

Present with 752 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • unfolded protein binding Source: SGD

GO - Biological processi

Enzyme and pathway databases

BioCyciYEAST:G3O-31113-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Vacuolar ATPase assembly protein VMA22
Gene namesi
Name:VMA22
Ordered Locus Names:YHR060W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VIII

Organism-specific databases

EuPathDBiFungiDB:YHR060W
SGDiS000001102 VMA22

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000658761 – 181Vacuolar ATPase assembly protein VMA22Add BLAST181
Isoform 2 (identifier: P38784-2)
Initiator methionineiRemovedCombined sources

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Isoform 2 (identifier: P38784-2)
Modified residuei2N-acetylalanineCombined sources1

Keywords - PTMi

Acetylation

Proteomic databases

MaxQBiP38784
PaxDbiP38784
PRIDEiP38784

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi36492, 115 interactors
DIPiDIP-1736N
IntActiP38784, 10 interactors
MINTiP38784
STRINGi4932.YHR060W

Structurei

3D structure databases

ProteinModelPortaliP38784
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000000873
InParanoidiP38784
OMAiRANYHNK
OrthoDBiEOG092C51XC

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative initiation. AlignAdd to basket
Isoform 1 (identifier: P38784-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSETRMAQNM DTTDEQYLRL IELLSNYDST LEQLQKGFQD GYIQLSRSNY
60 70 80 90 100
YNKDSLRGNY GEDYWDETYI GQLMATVEEK NSKVVVEIVK RKAQDKQEKK
110 120 130 140 150
EEEDNKLTQR KKGTKPEKQK TQSHKLKQDY DPILMFGGVL SVPSSLRQSQ
160 170 180
TSFKGCIPLI AQLINYKNEI LTLVETLSEQ E
Length:181
Mass (Da):21,078
Last modified:February 1, 1995 - v1
Checksum:iC1CB5DC8292D2734
GO
Isoform 2 (identifier: P38784-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-5: Missing.

Show »
Length:176
Mass (Da):20,473
Checksum:iB15B1BEB45347578
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0581231 – 5Missing in isoform 2. Curated5

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U24501 Genomic DNA Translation: AAA87458.1
U00061 Genomic DNA Translation: AAB68380.1
BK006934 Genomic DNA Translation: DAA06753.1
PIRiS46701
RefSeqiNP_011927.1, NM_001179190.1 [P38784-1]

Genome annotation databases

EnsemblFungiiYHR060W; YHR060W; YHR060W [P38784-1]
GeneIDi856457
KEGGisce:YHR060W

Keywords - Coding sequence diversityi

Alternative initiation

Similar proteinsi

Entry informationi

Entry nameiVMA22_YEAST
AccessioniPrimary (citable) accession number: P38784
Secondary accession number(s): D3DL09
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: May 23, 2018
This is version 129 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again