UniProtKB - P38760 (MIP6_YEAST)
Protein
RNA-binding protein MIP6
Gene
MIP6
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
Miscellaneous
Present with 98 molecules/cell in log phase SD medium.1 Publication
GO - Molecular functioni
- mRNA 3'-UTR binding Source: GO_Central
- poly(A) binding Source: GO_Central
- poly(U) RNA binding Source: GO_Central
- RNA binding Source: GO_Central
GO - Biological processi
- mRNA localization resulting in posttranscriptional regulation of gene expression Source: SGD
- mRNA metabolic process Source: SGD
- regulation of translation Source: SGD
Keywordsi
Molecular function | RNA-binding |
Names & Taxonomyi
Protein namesi | Recommended name: RNA-binding protein MIP6Alternative name(s): MEX67-interacting protein 6 |
Gene namesi | Name:MIP6 Ordered Locus Names:YHR015W |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
EuPathDBi | FungiDB:YHR015W |
SGDi | S000001057, MIP6 |
Subcellular locationi
Other locations
- Cytoplasm 1 Publication
Cytosol
- cytosol Source: GO_Central
Nucleus
- nucleus Source: GO_Central
Other locations
- cytoplasm Source: GO_Central
- cytoplasmic stress granule Source: GO_Central
- prospore membrane Source: SGD
- ribonucleoprotein complex Source: GO_Central
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000082032 | 1 – 659 | RNA-binding protein MIP6Add BLAST | 659 |
Proteomic databases
PaxDbi | P38760 |
PRIDEi | P38760 |
Interactioni
Subunit structurei
Interacts with MEX67.
1 PublicationProtein-protein interaction databases
BioGRIDi | 36444, 30 interactors |
DIPi | DIP-6647N |
IntActi | P38760, 2 interactors |
STRINGi | 4932.YHR015W |
Miscellaneous databases
RNActi | P38760, protein |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P38760 |
ModBasei | Search... |
PDBe-KBi | Search... |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 111 – 189 | RRM 1PROSITE-ProRule annotationAdd BLAST | 79 | |
Domaini | 199 – 267 | RRM 2PROSITE-ProRule annotationAdd BLAST | 69 | |
Domaini | 313 – 389 | RRM 3PROSITE-ProRule annotationAdd BLAST | 77 |
Keywords - Domaini
RepeatPhylogenomic databases
eggNOGi | KOG0123, Eukaryota |
GeneTreei | ENSGT00940000176742 |
HOGENOMi | CLU_020939_0_0_1 |
InParanoidi | P38760 |
OMAi | NIGSICT |
Family and domain databases
Gene3Di | 3.30.70.330, 4 hits |
InterProi | View protein in InterPro IPR012677, Nucleotide-bd_a/b_plait_sf IPR035979, RBD_domain_sf IPR000504, RRM_dom |
Pfami | View protein in Pfam PF00076, RRM_1, 3 hits |
SMARTi | View protein in SMART SM00360, RRM, 4 hits |
SUPFAMi | SSF54928, SSF54928, 2 hits |
PROSITEi | View protein in PROSITE PS50102, RRM, 3 hits |
i Sequence
Sequence statusi: Complete.
P38760-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPNSHGNVLN NISLNSKQNP RSISKSCPND KDARQKSFKT ISAQALVRVQ
60 70 80 90 100
GAGYKLGDVK LKDAEVKEKN SLKKYDCKNA TQEKKEQEQV FEKTVAKGSV
110 120 130 140 150
QKYITKTSKT NSLFIGNLKS TVTEEMLRKI FKRYQSFESA KVCRDFLTKK
160 170 180 190 200
SLGYGYLNFK DKNDAESARK EFNYTVFFGQ EVKIMPSMKN TLFRKNIGTN
210 220 230 240 250
VFFSNLPLEN PQLTTRSFYL IMIEYGNVLS CLLERRKNIG FVYFDNDISA
260 270 280 290 300
RNVIKKYNNQ EFFGNKIICG LHFDKEVRTR PEFTKRKKMI GSDIVIEDEL
310 320 330 340 350
LASNNLSDNA RSKTILVKNL PSDTTQEEVL DYFSTIGPIK SVFISEKQAN
360 370 380 390 400
TPHKAFVTYK NEEESKKAQK CLNKTIFKNH TIWVGPGKDK PVHNQIGTNK
410 420 430 440 450
KTKVYLKNLS FNCNKEFISQ LCLQEKIRFS EIKITNYNSL NWTFCGHVEC
460 470 480 490 500
FSRSDAERLF NILDRRLIGS SLVEASWSKN NDNILNEIDY DDGNNNENYK
510 520 530 540 550
KLINISSMMR FRTQELSAHQ KGLTSQFQQV VSPFSSYSNS YTNMNSLVAT
560 570 580 590 600
PMKPHPAFNL ITNTVDEKLH QPKRTKQENA EILESLKKII NRNLQRISIS
610 620 630 640 650
GLNKEENLRS ISEFIFDVFW EHDSERLSHF LLMTNTSLES QKILQKQVTR
AAESLGFTV
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U10400 Genomic DNA Translation: AAB68942.1 BK006934 Genomic DNA Translation: DAA06704.1 |
PIRi | S46788 |
RefSeqi | NP_011879.1, NM_001179145.1 |
Genome annotation databases
EnsemblFungii | YHR015W_mRNA; YHR015W; YHR015W |
GeneIDi | 856408 |
KEGGi | sce:YHR015W |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U10400 Genomic DNA Translation: AAB68942.1 BK006934 Genomic DNA Translation: DAA06704.1 |
PIRi | S46788 |
RefSeqi | NP_011879.1, NM_001179145.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
5D77 | X-ray | 1.30 | A | 313-388 | [»] | |
5D78 | X-ray | 1.25 | A | 313-387 | [»] | |
SMRi | P38760 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 36444, 30 interactors |
DIPi | DIP-6647N |
IntActi | P38760, 2 interactors |
STRINGi | 4932.YHR015W |
Proteomic databases
PaxDbi | P38760 |
PRIDEi | P38760 |
Genome annotation databases
EnsemblFungii | YHR015W_mRNA; YHR015W; YHR015W |
GeneIDi | 856408 |
KEGGi | sce:YHR015W |
Organism-specific databases
EuPathDBi | FungiDB:YHR015W |
SGDi | S000001057, MIP6 |
Phylogenomic databases
eggNOGi | KOG0123, Eukaryota |
GeneTreei | ENSGT00940000176742 |
HOGENOMi | CLU_020939_0_0_1 |
InParanoidi | P38760 |
OMAi | NIGSICT |
Miscellaneous databases
PROi | PR:P38760 |
RNActi | P38760, protein |
Family and domain databases
Gene3Di | 3.30.70.330, 4 hits |
InterProi | View protein in InterPro IPR012677, Nucleotide-bd_a/b_plait_sf IPR035979, RBD_domain_sf IPR000504, RRM_dom |
Pfami | View protein in Pfam PF00076, RRM_1, 3 hits |
SMARTi | View protein in SMART SM00360, RRM, 4 hits |
SUPFAMi | SSF54928, SSF54928, 2 hits |
PROSITEi | View protein in PROSITE PS50102, RRM, 3 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | MIP6_YEAST | |
Accessioni | P38760Primary (citable) accession number: P38760 Secondary accession number(s): D3DKW0 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1995 |
Last sequence update: | February 1, 1995 | |
Last modified: | October 7, 2020 | |
This is version 158 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD - Yeast chromosome VIII
Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names