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Entry version 164 (07 Oct 2020)
Sequence version 1 (01 Feb 1995)
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Protein

Protein STB5

Gene

STB5

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Binds to SIN3.

Miscellaneous

Present with 279 molecules/cell in log phase SD medium.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position and type of each DNA-binding domain present within the protein.<p><a href='/help/dna_bind' target='_top'>More...</a></p>DNA bindingi22 – 49Zn(2)-C6 fungal-typePROSITE-ProRule annotationAdd BLAST28

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein STB5
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:STB5
Ordered Locus Names:YHR178W
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559292 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome VIII

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
FungiDB:YHR178W

Saccharomyces Genome Database

More...
SGDi
S000001221, STB5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001149781 – 743Protein STB5Add BLAST743

Proteomic databases

MaxQB - The MaxQuant DataBase

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MaxQBi
P38699

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P38699

PRoteomics IDEntifications database

More...
PRIDEi
P38699

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P38699

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
36611, 671 interactors

Database of interacting proteins

More...
DIPi
DIP-827N

Protein interaction database and analysis system

More...
IntActi
P38699, 3 interactors

Molecular INTeraction database

More...
MINTi
P38699

STRING: functional protein association networks

More...
STRINGi
4932.YHR178W

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
P38699, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
P38699

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QTEH, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000176581

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_011881_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P38699

Identification of Orthologs from Complete Genome Data

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OMAi
TCYCIDR

Family and domain databases

Conserved Domains Database

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CDDi
cd00067, GAL4, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
4.10.240.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007219, Transcription_factor_dom_fun
IPR001138, Zn2-C6_fun-type_DNA-bd
IPR036864, Zn2-C6_fun-type_DNA-bd_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04082, Fungal_trans, 1 hit
PF00172, Zn_clus, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00906, Fungal_trans, 1 hit
SM00066, GAL4, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57701, SSF57701, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00463, ZN2_CY6_FUNGAL_1, 1 hit
PS50048, ZN2_CY6_FUNGAL_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P38699-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDGPNFAHQG GRSQRTTELY SCARCRKLKK KCGKQIPTCA NCDKNGAHCS
60 70 80 90 100
YPGRAPRRTK KELADAMLRG EYVPVKRNKK VGKSPLSTKS MPNSSSPLSA
110 120 130 140 150
NGAITPGFSP YENDDAHKMK QLKPSDPINL VMGASPNSSE GVSSLISVLT
160 170 180 190 200
SLNDNSNPSS HLSSNENSMI PSRSLPASVQ QSSTTSSFGG YNTPSPLISS
210 220 230 240 250
HVPANAQAVP LQNNNRNTSN GDNGSNVNHD NNNGSTNTPQ LSLTPYANNS
260 270 280 290 300
APNGKFDSVP VDASSIEFET MSCCFKGGRT TSWVREDGSF KSIDRSLLDR
310 320 330 340 350
FIAAYFKHNH RLFPMIDKIA FLNDAATITD FERLYDNKNY PDSFVFKVYM
360 370 380 390 400
IMAIGCTTLQ RAGMVSQDEE CLSEHLAFLA MKKFRSVIIL QDIETVRCLL
410 420 430 440 450
LLGIYSFFEP KGSSSWTISG IIMRLTIGLG LNRELTAKKL KSMSALEAEA
460 470 480 490 500
RYRVFWSAYC FERLVCTSLG RISGIDDEDI TVPLPRALYV DERDDLEMTK
510 520 530 540 550
LMISLRKMGG RIYKQVHSVS AGRQKLTIEQ KQEIISGLRK ELDEIYSRES
560 570 580 590 600
ERRKLKKSQM DQVERENNST TNVISFHSSE IWLAMRYSQL QILLYRPSAL
610 620 630 640 650
MPKPPIDSLS TLGEFCLQAW KHTYTLYKKR LLPLNWITLF RTLTICNTIL
660 670 680 690 700
YCLCQWSIDL IESKIEIQQC VEILRHFGER WIFAMRCADV FQNISNTILD
710 720 730 740
ISLSHGKVPN MDQLTRELFG ASDSYQDILD ENNVDVSWVD KLV
Length:743
Mass (Da):83,473
Last modified:February 1, 1995 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF1777001EA3E0432
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U00027 Genomic DNA Translation: AAB68023.1
BK006934 Genomic DNA Translation: DAA06871.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S48917

NCBI Reference Sequences

More...
RefSeqi
NP_012048.3, NM_001179309.3

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
YHR178W_mRNA; YHR178W; YHR178W

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
856583

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
sce:YHR178W

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00027 Genomic DNA Translation: AAB68023.1
BK006934 Genomic DNA Translation: DAA06871.1
PIRiS48917
RefSeqiNP_012048.3, NM_001179309.3

3D structure databases

SMRiP38699
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi36611, 671 interactors
DIPiDIP-827N
IntActiP38699, 3 interactors
MINTiP38699
STRINGi4932.YHR178W

PTM databases

iPTMnetiP38699

Proteomic databases

MaxQBiP38699
PaxDbiP38699
PRIDEiP38699

Genome annotation databases

EnsemblFungiiYHR178W_mRNA; YHR178W; YHR178W
GeneIDi856583
KEGGisce:YHR178W

Organism-specific databases

EuPathDBiFungiDB:YHR178W
SGDiS000001221, STB5

Phylogenomic databases

eggNOGiENOG502QTEH, Eukaryota
GeneTreeiENSGT00940000176581
HOGENOMiCLU_011881_0_0_1
InParanoidiP38699
OMAiTCYCIDR

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P38699
RNActiP38699, protein

Family and domain databases

CDDicd00067, GAL4, 1 hit
Gene3Di4.10.240.10, 1 hit
InterProiView protein in InterPro
IPR007219, Transcription_factor_dom_fun
IPR001138, Zn2-C6_fun-type_DNA-bd
IPR036864, Zn2-C6_fun-type_DNA-bd_sf
PfamiView protein in Pfam
PF04082, Fungal_trans, 1 hit
PF00172, Zn_clus, 1 hit
SMARTiView protein in SMART
SM00906, Fungal_trans, 1 hit
SM00066, GAL4, 1 hit
SUPFAMiSSF57701, SSF57701, 1 hit
PROSITEiView protein in PROSITE
PS00463, ZN2_CY6_FUNGAL_1, 1 hit
PS50048, ZN2_CY6_FUNGAL_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSTB5_YEAST
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P38699
Secondary accession number(s): D3DLC7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: October 7, 2020
This is version 164 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome VIII
    Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names
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