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UniProtKB - P38156 (MAL31_YEAST)
Protein
Maltose permease MAL31
Gene
MAL31
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
High-affinity uptake of maltose and maltotriose. Also transports turanose but not alpha-methylglucoside, melezitose or trehalose.
1 PublicationGO - Molecular functioni
- alpha-glucoside:proton symporter activity Source: SGD
- carbohydrate:proton symporter activity Source: GO_Central
GO - Biological processi
- alpha-glucoside transport Source: SGD
- carbohydrate transport Source: GO_Central
- maltose metabolic process Source: UniProtKB-KW
Keywordsi
Biological process | Maltose metabolism, Sugar transport, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Maltose permease MAL31Alternative name(s): Maltose transport protein MAL31 |
Gene namesi | Name:MAL31 Synonyms:MAL3T Ordered Locus Names:YBR298C ORF Names:YBR2116 |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
SGDi | S000000502, MAL31 |
VEuPathDBi | FungiDB:YBR298C |
Subcellular locationi
Other locations
Other locations
- cell periphery Source: SGD
- integral component of membrane Source: UniProtKB-KW
- membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 108 | CytoplasmicSequence analysisAdd BLAST | 108 | |
Transmembranei | 109 – 129 | Helical; Name=1Sequence analysisAdd BLAST | 21 | |
Topological domaini | 130 – 144 | ExtracellularSequence analysisAdd BLAST | 15 | |
Transmembranei | 145 – 165 | Helical; Name=2Sequence analysisAdd BLAST | 21 | |
Topological domaini | 166 – 180 | CytoplasmicSequence analysisAdd BLAST | 15 | |
Transmembranei | 181 – 201 | Helical; Name=3Sequence analysisAdd BLAST | 21 | |
Topological domaini | 202 | ExtracellularSequence analysis | 1 | |
Transmembranei | 203 – 223 | Helical; Name=4Sequence analysisAdd BLAST | 21 | |
Topological domaini | 224 – 236 | CytoplasmicSequence analysisAdd BLAST | 13 | |
Transmembranei | 237 – 257 | Helical; Name=5Sequence analysisAdd BLAST | 21 | |
Topological domaini | 258 – 272 | ExtracellularSequence analysisAdd BLAST | 15 | |
Transmembranei | 273 – 293 | Helical; Name=6Sequence analysisAdd BLAST | 21 | |
Topological domaini | 294 – 364 | CytoplasmicSequence analysisAdd BLAST | 71 | |
Transmembranei | 365 – 385 | Helical; Name=7Sequence analysisAdd BLAST | 21 | |
Topological domaini | 386 – 398 | ExtracellularSequence analysisAdd BLAST | 13 | |
Transmembranei | 399 – 419 | Helical; Name=8Sequence analysisAdd BLAST | 21 | |
Topological domaini | 420 – 427 | CytoplasmicSequence analysis | 8 | |
Transmembranei | 428 – 448 | Helical; Name=9Sequence analysisAdd BLAST | 21 | |
Topological domaini | 449 – 460 | ExtracellularSequence analysisAdd BLAST | 12 | |
Transmembranei | 461 – 481 | Helical; Name=10Sequence analysisAdd BLAST | 21 | |
Topological domaini | 482 – 493 | CytoplasmicSequence analysisAdd BLAST | 12 | |
Transmembranei | 494 – 514 | Helical; Name=11Sequence analysisAdd BLAST | 21 | |
Topological domaini | 515 – 526 | ExtracellularSequence analysisAdd BLAST | 12 | |
Transmembranei | 527 – 547 | Helical; Name=12Sequence analysisAdd BLAST | 21 | |
Topological domaini | 548 – 614 | CytoplasmicSequence analysisAdd BLAST | 67 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000050422 | 1 – 614 | Maltose permease MAL31Add BLAST | 614 |
Proteomic databases
PaxDbi | P38156 |
PRIDEi | P38156 |
Expressioni
Inductioni
By maltose and maltotriose. Repressed by glucose.1 Publication
Interactioni
Protein-protein interaction databases
BioGRIDi | 32991, 84 interactors |
DIPi | DIP-7544N |
IntActi | P38156, 16 interactors |
MINTi | P38156 |
STRINGi | 4932.YBR298C |
Miscellaneous databases
RNActi | P38156, protein |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 48 | DisorderedSequence analysisAdd BLAST | 48 | |
Regioni | 595 – 614 | DisorderedSequence analysisAdd BLAST | 20 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 23 | Basic and acidic residuesSequence analysisAdd BLAST | 23 |
Sequence similaritiesi
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0254, Eukaryota |
GeneTreei | ENSGT00940000176341 |
HOGENOMi | CLU_001265_11_5_1 |
InParanoidi | P38156 |
OMAi | WNWGART |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR003663, Sugar/inositol_transpt IPR005829, Sugar_transporter_CS |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00879, SP, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00217, SUGAR_TRANSPORT_2, 1 hit |
i Sequence
Sequence statusi: Complete.
P38156-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKGLSSLINR KKDRNDSHLD EIENGVNATE FNSIEMEEQG KKSDFDLSHL
60 70 80 90 100
EYGPGSLIPN DNNEEVPDLL DEAMQDAKEA DESERGMPLM TALKTYPKAA
110 120 130 140 150
AWSLLVSTTL IQEGYDTAIL GAFYALPVFQ KKYGSLNSNT GDYEISVSWQ
160 170 180 190 200
IGLCLCYMAG EIVGLQMTGP SVDYMGNRYT LIMALFFLAA FIFILYFCKS
210 220 230 240 250
LGMIAVGQAL CGMPWGCFQC LTVSYASEIC PLALRYYLTT YSNLCWAFGQ
260 270 280 290 300
LFAAGIMKNS QNKYANSELG YKLPFALQWI WPLPLAVGIF FAPESPWWLV
310 320 330 340 350
KKGRIDQARR SLERTLSGKG PEKELLVSME LDKIKTTIEK EQKMSDEGTY
360 370 380 390 400
WDCVKDGINR RRTRIACLCW IGQCSCGASL IGYSTYFYEK AGVSTDTAFT
410 420 430 440 450
FSIIQYCLGI AATFISWWAS KYCGRFDLYA FGLAFQAIMF FIIGGLGCSD
460 470 480 490 500
THGAKMGSGA LLMVVAFFYN LGIAPVVFCL VSEIPSSRLR TKTIILARNA
510 520 530 540 550
YNVIQVVVTV LIMYQLNSEK WNWGAKSGFF WGGFCLATLA WAVVDLPETA
560 570 580 590 600
GRTFIEINEL FRLGVPARKF KSTKVDPFAA AKAAAAEINV KDPKEDLETS
610
VVDEGRNTSS VVNK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | DQ010169 Genomic DNA Translation: AAY67702.1 Z36167 Genomic DNA Translation: CAA85263.1 AY692794 Genomic DNA Translation: AAT92813.1 BK006936 Genomic DNA Translation: DAA07413.1 |
PIRi | S46182 |
RefSeqi | NP_009857.1, NM_001178646.1 |
Genome annotation databases
EnsemblFungii | YBR298C_mRNA; YBR298C; YBR298C |
GeneIDi | 852601 |
KEGGi | sce:YBR298C |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | DQ010169 Genomic DNA Translation: AAY67702.1 Z36167 Genomic DNA Translation: CAA85263.1 AY692794 Genomic DNA Translation: AAT92813.1 BK006936 Genomic DNA Translation: DAA07413.1 |
PIRi | S46182 |
RefSeqi | NP_009857.1, NM_001178646.1 |
3D structure databases
SMRi | P38156 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 32991, 84 interactors |
DIPi | DIP-7544N |
IntActi | P38156, 16 interactors |
MINTi | P38156 |
STRINGi | 4932.YBR298C |
Proteomic databases
PaxDbi | P38156 |
PRIDEi | P38156 |
Genome annotation databases
EnsemblFungii | YBR298C_mRNA; YBR298C; YBR298C |
GeneIDi | 852601 |
KEGGi | sce:YBR298C |
Organism-specific databases
SGDi | S000000502, MAL31 |
VEuPathDBi | FungiDB:YBR298C |
Phylogenomic databases
eggNOGi | KOG0254, Eukaryota |
GeneTreei | ENSGT00940000176341 |
HOGENOMi | CLU_001265_11_5_1 |
InParanoidi | P38156 |
OMAi | WNWGART |
Miscellaneous databases
PROi | PR:P38156 |
RNActi | P38156, protein |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR003663, Sugar/inositol_transpt IPR005829, Sugar_transporter_CS |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00879, SP, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00217, SUGAR_TRANSPORT_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | MAL31_YEAST | |
Accessioni | P38156Primary (citable) accession number: P38156 Secondary accession number(s): D6VQU3, Q3SCJ3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1994 |
Last sequence update: | October 1, 1994 | |
Last modified: | February 23, 2022 | |
This is version 162 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD - Yeast chromosome II
Yeast (Saccharomyces cerevisiae) chromosome II: entries and gene names - SIMILARITY comments
Index of protein domains and families