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Entry version 160 (02 Jun 2021)
Sequence version 1 (01 Oct 1994)
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Protein

Probable metabolite transport protein YBR241C

Gene

YBR241C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTransport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-SCE-189200, Cellular hexose transport
R-SCE-196836, Vitamin C (ascorbate) metabolism
R-SCE-422356, Regulation of insulin secretion
R-SCE-5653890, Lactose synthesis
R-SCE-6798695, Neutrophil degranulation
R-SCE-8981373, Intestinal hexose absorption

Protein family/group databases

Transport Classification Database

More...
TCDBi
2.A.1.1.96, the major facilitator superfamily (mfs)

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Probable metabolite transport protein YBR241C
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:YBR241C
ORF Names:YBR1625
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559292 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome II

Organism-specific databases

Saccharomyces Genome Database

More...
SGDi
S000000445, YBR241C

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
FungiDB:YBR241C

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 18CytoplasmicSequence analysisAdd BLAST18
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei19 – 39Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini40 – 87VacuolarSequence analysisAdd BLAST48
Transmembranei88 – 108Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini109 – 121CytoplasmicSequence analysisAdd BLAST13
Transmembranei122 – 142Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini143 – 146VacuolarSequence analysis4
Transmembranei147 – 167Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini168 – 178CytoplasmicSequence analysisAdd BLAST11
Transmembranei179 – 198Helical; Name=5Sequence analysisAdd BLAST20
Topological domaini199 – 204VacuolarSequence analysis6
Transmembranei205 – 225Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini226 – 299CytoplasmicSequence analysisAdd BLAST74
Transmembranei300 – 320Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini321 – 322VacuolarSequence analysis2
Transmembranei323 – 337Helical; Name=8Sequence analysisAdd BLAST15
Topological domaini338 – 344CytoplasmicSequence analysis7
Transmembranei345 – 364Helical; Name=9Sequence analysisAdd BLAST20
Topological domaini365 – 390VacuolarSequence analysisAdd BLAST26
Transmembranei391 – 411Helical; Name=10Sequence analysisAdd BLAST21
Topological domaini412 – 419CytoplasmicSequence analysis8
Transmembranei420 – 442Helical; Name=11Sequence analysisAdd BLAST23
Topological domaini443 – 446VacuolarSequence analysis4
Transmembranei447 – 463Helical; Name=12Sequence analysisAdd BLAST17
Topological domaini464 – 488CytoplasmicSequence analysisAdd BLAST25

Keywords - Cellular componenti

Membrane, Vacuole

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000504631 – 488Probable metabolite transport protein YBR241CAdd BLAST488

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi63N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P38142

PRoteomics IDEntifications database

More...
PRIDEi
P38142

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
32936, 33 interactors

Database of interacting proteins

More...
DIPi
DIP-5363N

Protein interaction database and analysis system

More...
IntActi
P38142, 10 interactors

Molecular INTeraction database

More...
MINTi
P38142

STRING: functional protein association networks

More...
STRINGi
4932.YBR241C

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
P38142, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni258 – 281DisorderedSequence analysisAdd BLAST24

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi261 – 277Basic and acidic residuesSequence analysisAdd BLAST17

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0569, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000166877

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_001265_30_5_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P38142

Identification of Orthologs from Complete Genome Data

More...
OMAi
AVEMKFL

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR020846, MFS_dom
IPR005828, MFS_sugar_transport-like
IPR036259, MFS_trans_sf
IPR003663, Sugar/inositol_transpt
IPR005829, Sugar_transporter_CS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00083, Sugar_tr, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00171, SUGRTRNSPORT

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF103473, SSF103473, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00879, SP, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50850, MFS, 1 hit
PS00216, SUGAR_TRANSPORT_1, 1 hit
PS00217, SUGAR_TRANSPORT_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P38142-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAETERLMPN GGSRETKPLI TGHLILGTIV ACLGSIQYGY HIAELNAPQE
60 70 80 90 100
FLSCSRFEAP DENISYDDTW VGQHGLKQCI ALTDSQYGAI TSIFSIGGLF
110 120 130 140 150
GSYYAGNWAN RYGRKYVSMG ASAMCMVSSL LLFFSNSYLQ LLFGRFLVGM
160 170 180 190 200
SCGTAIVITP LFINEIAPVE WRGAMGSMNQ VSINLGILLT QTLALKYADS
210 220 230 240 250
YNWRWLLFSG SVIAVANILA WLKVDESPRW LVSHGFVSEA ETALFKLRPG
260 270 280 290 300
TYQQAKQEIQ DWQRSHGHNR DPESSEETHS GPTLWQYVTD PSYKKPRTVI
310 320 330 340 350
LAILSCQQFC GINSIIFYGV KVIGKILPDY SIQVNFAISI LNVVVTLAAS
360 370 380 390 400
AIIDHVGRRP LLLASTTVMT AMSLLISVGL TLSVSFLLVT ATFVYIAAFA
410 420 430 440 450
IGLGPIPFLI IGELSYPQDA ATAQSFGTVC NWLATFIVGY LFPIGHGLMG
460 470 480
GYVFAIFAAI AAMFATYVYK RVPETKGKTT YSEVWAGY
Length:488
Mass (Da):53,526
Last modified:October 1, 1994 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF74A2E3676363BE5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti438V → A in AAT92614 (PubMed:17322287).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
Z36110 Genomic DNA Translation: CAA85204.1
AY692595 Genomic DNA Translation: AAT92614.1
BK006936 Genomic DNA Translation: DAA07357.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S46118

NCBI Reference Sequences

More...
RefSeqi
NP_009800.1, NM_001178589.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
YBR241C_mRNA; YBR241C; YBR241C

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
852543

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
sce:YBR241C

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z36110 Genomic DNA Translation: CAA85204.1
AY692595 Genomic DNA Translation: AAT92614.1
BK006936 Genomic DNA Translation: DAA07357.1
PIRiS46118
RefSeqiNP_009800.1, NM_001178589.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi32936, 33 interactors
DIPiDIP-5363N
IntActiP38142, 10 interactors
MINTiP38142
STRINGi4932.YBR241C

Protein family/group databases

TCDBi2.A.1.1.96, the major facilitator superfamily (mfs)

Proteomic databases

PaxDbiP38142
PRIDEiP38142

Genome annotation databases

EnsemblFungiiYBR241C_mRNA; YBR241C; YBR241C
GeneIDi852543
KEGGisce:YBR241C

Organism-specific databases

SGDiS000000445, YBR241C
VEuPathDBiFungiDB:YBR241C

Phylogenomic databases

eggNOGiKOG0569, Eukaryota
GeneTreeiENSGT00940000166877
HOGENOMiCLU_001265_30_5_1
InParanoidiP38142
OMAiAVEMKFL

Enzyme and pathway databases

ReactomeiR-SCE-189200, Cellular hexose transport
R-SCE-196836, Vitamin C (ascorbate) metabolism
R-SCE-422356, Regulation of insulin secretion
R-SCE-5653890, Lactose synthesis
R-SCE-6798695, Neutrophil degranulation
R-SCE-8981373, Intestinal hexose absorption

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P38142
RNActiP38142, protein

Family and domain databases

InterProiView protein in InterPro
IPR020846, MFS_dom
IPR005828, MFS_sugar_transport-like
IPR036259, MFS_trans_sf
IPR003663, Sugar/inositol_transpt
IPR005829, Sugar_transporter_CS
PfamiView protein in Pfam
PF00083, Sugar_tr, 1 hit
PRINTSiPR00171, SUGRTRNSPORT
SUPFAMiSSF103473, SSF103473, 1 hit
TIGRFAMsiTIGR00879, SP, 1 hit
PROSITEiView protein in PROSITE
PS50850, MFS, 1 hit
PS00216, SUGAR_TRANSPORT_1, 1 hit
PS00217, SUGAR_TRANSPORT_2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYB91_YEAST
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P38142
Secondary accession number(s): D6VQN7, Q6B2Y5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: June 2, 2021
This is version 160 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome II
    Yeast (Saccharomyces cerevisiae) chromosome II: entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families
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