UniProtKB - P38105 (RSPB_ECOLI)
Protein
Starvation-sensing protein RspB
Gene
rspB
Organism
Escherichia coli (strain K12)
Status
Functioni
Not known; probable catabolic enzyme.
Cofactori
Zn2+By similarityNote: Binds 2 Zn2+ ions per subunit.By similarity
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 37 | Zinc 1; catalyticBy similarity | 1 | |
Metal bindingi | 59 | Zinc 1; catalyticBy similarity | 1 | |
Metal bindingi | 89 | Zinc 2By similarity | 1 | |
Metal bindingi | 92 | Zinc 2By similarity | 1 | |
Metal bindingi | 95 | Zinc 2By similarity | 1 | |
Metal bindingi | 103 | Zinc 2By similarity | 1 | |
Metal bindingi | 144 | Zinc 1; catalyticBy similarity | 1 |
GO - Molecular functioni
- galactitol-1-phosphate 5-dehydrogenase activity Source: GO_Central
- zinc ion binding Source: InterPro
Keywordsi
Molecular function | Oxidoreductase |
Ligand | Metal-binding, Zinc |
Enzyme and pathway databases
BioCyci | EcoCyc:G6838-MONOMER |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:rspB1 Publication Ordered Locus Names:b1580, JW1572 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000160900 | 1 – 339 | Starvation-sensing protein RspBAdd BLAST | 339 |
Proteomic databases
PaxDbi | P38105 |
PRIDEi | P38105 |
Expressioni
Inductioni
Repressed by RspR.1 Publication
Interactioni
Protein-protein interaction databases
BioGRIDi | 4260232, 14 interactors 850487, 1 interactor |
IntActi | P38105, 1 interactor |
STRINGi | 511145.b1580 |
Family & Domainsi
Sequence similaritiesi
Belongs to the zinc-containing alcohol dehydrogenase family.Curated
Phylogenomic databases
eggNOGi | COG1063, Bacteria |
HOGENOMi | CLU_026673_11_0_6 |
InParanoidi | P38105 |
PhylomeDBi | P38105 |
Family and domain databases
InterProi | View protein in InterPro IPR013149, ADH_C IPR013154, ADH_N IPR002328, ADH_Zn_CS IPR011032, GroES-like_sf IPR036291, NAD(P)-bd_dom_sf |
Pfami | View protein in Pfam PF08240, ADH_N, 1 hit PF00107, ADH_zinc_N, 1 hit |
SUPFAMi | SSF50129, SSF50129, 1 hit SSF51735, SSF51735, 1 hit |
PROSITEi | View protein in PROSITE PS00059, ADH_ZINC, 1 hit |
i Sequence
Sequence statusi: Complete.
P38105-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKSILIEKPN QLAIVEREIP TPSAGEVRVK VKLAGICGSD SHIYRGHNPF
60 70 80 90 100
AKYPRVIGHE FFGVIDAVGE GVESARVGER VAVDPVVSCG HCYPCSIGKP
110 120 130 140 150
NVCTTLAVLG VHADGGFSEY AVVPAKNAWK IPEAVADQYA VMIEPFTIAA
160 170 180 190 200
NVTGHGQPTE NDTVLVYGAG PIGLTIVQVL KGVYNVKNVI VADRIDERLE
210 220 230 240 250
KAKESGADWA INNSQTPLGE IFTEKGIKPT LIIDAACHPS ILKEAVTLAS
260 270 280 290 300
PAARIVLMGF SSEPSEVIQQ GITGKELSIF SSRLNANKFP IVIDWLSKGL
310 320 330
IKPEKLITHT FDFQHVADAI SLFEQDQKHC CKVLLTFSE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L31628 Genomic DNA Translation: AAA21686.1 U00096 Genomic DNA Translation: AAC74652.1 AP009048 Genomic DNA Translation: BAA15284.1 |
PIRi | I81185 |
RefSeqi | NP_416097.1, NC_000913.3 WP_000836066.1, NZ_SSZK01000001.1 |
Genome annotation databases
EnsemblBacteriai | AAC74652; AAC74652; b1580 BAA15284; BAA15284; BAA15284 |
GeneIDi | 57730973 946127 |
KEGGi | ecj:JW1572 eco:b1580 |
PATRICi | fig|1411691.4.peg.682 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L31628 Genomic DNA Translation: AAA21686.1 U00096 Genomic DNA Translation: AAC74652.1 AP009048 Genomic DNA Translation: BAA15284.1 |
PIRi | I81185 |
RefSeqi | NP_416097.1, NC_000913.3 WP_000836066.1, NZ_SSZK01000001.1 |
3D structure databases
SMRi | P38105 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4260232, 14 interactors 850487, 1 interactor |
IntActi | P38105, 1 interactor |
STRINGi | 511145.b1580 |
Proteomic databases
PaxDbi | P38105 |
PRIDEi | P38105 |
Genome annotation databases
EnsemblBacteriai | AAC74652; AAC74652; b1580 BAA15284; BAA15284; BAA15284 |
GeneIDi | 57730973 946127 |
KEGGi | ecj:JW1572 eco:b1580 |
PATRICi | fig|1411691.4.peg.682 |
Organism-specific databases
EchoBASEi | EB2346 |
Phylogenomic databases
eggNOGi | COG1063, Bacteria |
HOGENOMi | CLU_026673_11_0_6 |
InParanoidi | P38105 |
PhylomeDBi | P38105 |
Enzyme and pathway databases
BioCyci | EcoCyc:G6838-MONOMER |
Miscellaneous databases
PROi | PR:P38105 |
Family and domain databases
InterProi | View protein in InterPro IPR013149, ADH_C IPR013154, ADH_N IPR002328, ADH_Zn_CS IPR011032, GroES-like_sf IPR036291, NAD(P)-bd_dom_sf |
Pfami | View protein in Pfam PF08240, ADH_N, 1 hit PF00107, ADH_zinc_N, 1 hit |
SUPFAMi | SSF50129, SSF50129, 1 hit SSF51735, SSF51735, 1 hit |
PROSITEi | View protein in PROSITE PS00059, ADH_ZINC, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | RSPB_ECOLI | |
Accessioni | P38105Primary (citable) accession number: P38105 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1994 |
Last sequence update: | October 1, 1994 | |
Last modified: | February 10, 2021 | |
This is version 144 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families