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UniProtKB - P38087 (YMC2_YEAST)
Protein
Carrier protein YMC2, mitochondrial
Gene
YMC2
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
Miscellaneous
Present with 1050 molecules/cell in log phase SD medium.1 Publication
GO - Molecular functioni
- L-ornithine transmembrane transporter activity Source: GO_Central
- organic acid transmembrane transporter activity Source: SGD
GO - Biological processi
- mitochondrial L-ornithine transmembrane transport Source: GO_Central
- mitochondrial transport Source: SGD
- transmembrane transport Source: SGD
Keywordsi
Biological process | Transport |
Enzyme and pathway databases
Reactomei | R-SCE-70635, Urea cycle |
Protein family/group databases
TCDBi | 2.A.29.8.11, the mitochondrial carrier (mc) family |
Names & Taxonomyi
Protein namesi | Recommended name: Carrier protein YMC2, mitochondrial |
Gene namesi | Name:YMC2 Ordered Locus Names:YBR104W ORF Names:YBR0833 |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
SGDi | S000000308, YMC2 |
VEuPathDBi | FungiDB:YBR104W |
Subcellular locationi
Mitochondrion
- Mitochondrion inner membrane Curated; Multi-pass membrane protein Curated
Mitochondrion
- mitochondrial inner membrane Source: UniProtKB-SubCell
- mitochondrion Source: SGD
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 38 – 58 | Helical; Name=1Sequence analysisAdd BLAST | 21 | |
Transmembranei | 84 – 104 | Helical; Name=2Sequence analysisAdd BLAST | 21 | |
Transmembranei | 140 – 160 | Helical; Name=3Sequence analysisAdd BLAST | 21 | |
Transmembranei | 205 – 225 | Helical; Name=5Sequence analysisAdd BLAST | 21 | |
Transmembranei | 243 – 263 | Helical; Name=6Sequence analysisAdd BLAST | 21 | |
Transmembranei | 297 – 318 | Helical; Name=1Sequence analysisAdd BLAST | 22 |
Keywords - Cellular componenti
Membrane, Mitochondrion, Mitochondrion inner membranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transit peptidei | 1 – 33 | MitochondrionSequence analysisAdd BLAST | 33 | |
ChainiPRO_0000019266 | 34 – 329 | Carrier protein YMC2, mitochondrialAdd BLAST | 296 |
Proteomic databases
MaxQBi | P38087 |
PaxDbi | P38087 |
PRIDEi | P38087 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 32808, 81 interactors |
IntActi | P38087, 6 interactors |
STRINGi | 4932.YBR104W |
Miscellaneous databases
RNActi | P38087, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 34 – 115 | Solcar 1Add BLAST | 82 | |
Repeati | 143 – 226 | Solcar 2Add BLAST | 84 | |
Repeati | 238 – 325 | Solcar 3Add BLAST | 88 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 27 | DisorderedSequence analysisAdd BLAST | 27 |
Sequence similaritiesi
Keywords - Domaini
Repeat, Transit peptide, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0758, Eukaryota |
GeneTreei | ENSGT00940000176446 |
HOGENOMi | CLU_015166_16_2_1 |
InParanoidi | P38087 |
OMAi | GVGGMCN |
Family and domain databases
Gene3Di | 1.50.40.10, 2 hits |
InterProi | View protein in InterPro IPR018108, Mitochondrial_sb/sol_carrier IPR023395, Mt_carrier_dom_sf |
Pfami | View protein in Pfam PF00153, Mito_carr, 3 hits |
SUPFAMi | SSF103506, SSF103506, 1 hit |
PROSITEi | View protein in PROSITE PS50920, SOLCAR, 3 hits |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P38087-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSEEFPTPQL LDELEDQQKV TTPNEKRELS SNRVLKDIFA GTIGGIAQVL
60 70 80 90 100
VGQPFDTTKV RLQTATTRTT TLEVLRNLVK NEGVFAFYKG ALTPLLGVGI
110 120 130 140 150
CVSVQFGVNE AMKRFFQNYN ASKNPNMSSQ DVDLSRSNTL PLSQYYVCGL
160 170 180 190 200
TGGVVNSFLA SPIEQIRIRL QTQTSNGGDR EFKGPWDCIK KLKAQGGLMR
210 220 230 240 250
GLFPTMIRAG HGLGTYFLVY EALVAREIGT GLTRNEIPPW KLCLFGAFSG
260 270 280 290 300
TMLWLTVYPL DVVKSIIQND DLRKPKYKNS ISYVAKTIYA KEGIRAFFKG
310 320
FGPTMVRSAP VNGATFLTFE LVMRFLGEE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X78993 Genomic DNA Translation: CAA55607.1 Z35973 Genomic DNA Translation: CAA85059.1 AY693055 Genomic DNA Translation: AAT93074.1 BK006936 Genomic DNA Translation: DAA07223.1 |
PIRi | S48269 |
RefSeqi | NP_009662.3, NM_001178452.3 |
Genome annotation databases
EnsemblFungii | YBR104W_mRNA; YBR104W; YBR104W |
GeneIDi | 852401 |
KEGGi | sce:YBR104W |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X78993 Genomic DNA Translation: CAA55607.1 Z35973 Genomic DNA Translation: CAA85059.1 AY693055 Genomic DNA Translation: AAT93074.1 BK006936 Genomic DNA Translation: DAA07223.1 |
PIRi | S48269 |
RefSeqi | NP_009662.3, NM_001178452.3 |
3D structure databases
AlphaFoldDBi | P38087 |
SMRi | P38087 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 32808, 81 interactors |
IntActi | P38087, 6 interactors |
STRINGi | 4932.YBR104W |
Protein family/group databases
TCDBi | 2.A.29.8.11, the mitochondrial carrier (mc) family |
Proteomic databases
MaxQBi | P38087 |
PaxDbi | P38087 |
PRIDEi | P38087 |
Genome annotation databases
EnsemblFungii | YBR104W_mRNA; YBR104W; YBR104W |
GeneIDi | 852401 |
KEGGi | sce:YBR104W |
Organism-specific databases
SGDi | S000000308, YMC2 |
VEuPathDBi | FungiDB:YBR104W |
Phylogenomic databases
eggNOGi | KOG0758, Eukaryota |
GeneTreei | ENSGT00940000176446 |
HOGENOMi | CLU_015166_16_2_1 |
InParanoidi | P38087 |
OMAi | GVGGMCN |
Enzyme and pathway databases
Reactomei | R-SCE-70635, Urea cycle |
Miscellaneous databases
PROi | PR:P38087 |
RNActi | P38087, protein |
Family and domain databases
Gene3Di | 1.50.40.10, 2 hits |
InterProi | View protein in InterPro IPR018108, Mitochondrial_sb/sol_carrier IPR023395, Mt_carrier_dom_sf |
Pfami | View protein in Pfam PF00153, Mito_carr, 3 hits |
SUPFAMi | SSF103506, SSF103506, 1 hit |
PROSITEi | View protein in PROSITE PS50920, SOLCAR, 3 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | YMC2_YEAST | |
Accessioni | P38087Primary (citable) accession number: P38087 Secondary accession number(s): D6VQA3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1994 |
Last sequence update: | October 1, 1994 | |
Last modified: | May 25, 2022 | |
This is version 170 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD - Yeast chromosome II
Yeast (Saccharomyces cerevisiae) chromosome II: entries and gene names - SIMILARITY comments
Index of protein domains and families