UniProtKB - P37902 (GLTI_ECOLI)
Protein
Glutamate/aspartate import solute-binding protein
Gene
gltI
Organism
Escherichia coli (strain K12)
Status
Functioni
Part of the ABC transporter complex GltIJKL involved in glutamate and aspartate uptake. Binds to both glutamate and aspartate.1 Publication3 Publications
GO - Molecular functioni
- aspartate binding Source: EcoCyc
- glutamate binding Source: EcoCyc
GO - Biological processi
- L-aspartate transmembrane transport Source: EcoCyc
- L-glutamate transmembrane transport Source: EcoCyc
Keywordsi
Biological process | Amino-acid transport, Transport |
Enzyme and pathway databases
BioCyci | EcoCyc:G6359-MONOMER MetaCyc:G6359-MONOMER |
Protein family/group databases
TCDBi | 3.A.1.3.4, the atp-binding cassette (abc) superfamily |
Names & Taxonomyi
Protein namesi | Recommended name: Glutamate/aspartate import solute-binding proteinCurated |
Gene namesi | Name:gltI Synonyms:ybeJ, yzzK Ordered Locus Names:b0655, JW5092 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Other locations
- Periplasm 1 Publication
Other locations
- outer membrane-bounded periplasmic space Source: EcoCyc
Keywords - Cellular componenti
PeriplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 22 | 1 PublicationAdd BLAST | 22 | |
ChainiPRO_0000031758 | 23 – 302 | Glutamate/aspartate import solute-binding proteinAdd BLAST | 280 |
Proteomic databases
jPOSTi | P37902 |
PaxDbi | P37902 |
PRIDEi | P37902 |
2D gel databases
SWISS-2DPAGEi | P37902 |
Interactioni
Subunit structurei
The complex is composed of two ATP-binding proteins (GltL), two transmembrane proteins (GltJ and GltK) and a solute-binding protein (GltI).
1 PublicationProtein-protein interaction databases
BioGRIDi | 4260829, 18 interactors 851277, 2 interactors |
ComplexPortali | CPX-4324, Glutamate/aspartate ABC transporter complex |
DIPi | DIP-11361N |
IntActi | P37902, 1 interactor |
STRINGi | 511145.b0655 |
Family & Domainsi
Sequence similaritiesi
Belongs to the bacterial solute-binding protein 3 family.Curated
Keywords - Domaini
SignalPhylogenomic databases
eggNOGi | COG0834, Bacteria |
HOGENOMi | CLU_019602_0_0_6 |
InParanoidi | P37902 |
PhylomeDBi | P37902 |
Family and domain databases
InterProi | View protein in InterPro IPR001638, Solute-binding_3/MltF_N |
Pfami | View protein in Pfam PF00497, SBP_bac_3, 1 hit |
SMARTi | View protein in SMART SM00062, PBPb, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P37902-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MQLRKPATAI LALALSAGLA QADDAAPAAG STLDKIAKNG VIVVGHRESS
60 70 80 90 100
VPFSYYDNQQ KVVGYSQDYS NAIVEAVKKK LNKPDLQVKL IPITSQNRIP
110 120 130 140 150
LLQNGTFDFE CGSTTNNVER QKQAAFSDTI FVVGTRLLTK KGGDIKDFAN
160 170 180 190 200
LKDKAVVVTS GTTSEVLLNK LNEEQKMNMR IISAKDHGDS FRTLESGRAV
210 220 230 240 250
AFMMDDALLA GERAKAKKPD NWEIVGKPQS QEAYGCMLRK DDPQFKKLMD
260 270 280 290 300
DTIAQVQTSG EAEKWFDKWF KNPIPPKNLN MNFELSDEMK ALFKEPNDKA
LN
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U82598 Genomic DNA Translation: AAB40856.1 U00096 Genomic DNA Translation: AAC73756.1 AP009048 Genomic DNA Translation: BAA35307.2 U10981 Genomic DNA No translation available. |
PIRi | E64800 |
RefSeqi | NP_415188.1, NC_000913.3 WP_001177086.1, NZ_SSZK01000037.1 |
Genome annotation databases
EnsemblBacteriai | AAC73756; AAC73756; b0655 BAA35307; BAA35307; BAA35307 |
GeneIDi | 57728795 946938 |
KEGGi | ecj:JW5092 eco:b0655 |
PATRICi | fig|1411691.4.peg.1613 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U82598 Genomic DNA Translation: AAB40856.1 U00096 Genomic DNA Translation: AAC73756.1 AP009048 Genomic DNA Translation: BAA35307.2 U10981 Genomic DNA No translation available. |
PIRi | E64800 |
RefSeqi | NP_415188.1, NC_000913.3 WP_001177086.1, NZ_SSZK01000037.1 |
3D structure databases
SASBDBi | P37902 |
SMRi | P37902 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4260829, 18 interactors 851277, 2 interactors |
ComplexPortali | CPX-4324, Glutamate/aspartate ABC transporter complex |
DIPi | DIP-11361N |
IntActi | P37902, 1 interactor |
STRINGi | 511145.b0655 |
Protein family/group databases
TCDBi | 3.A.1.3.4, the atp-binding cassette (abc) superfamily |
2D gel databases
SWISS-2DPAGEi | P37902 |
Proteomic databases
jPOSTi | P37902 |
PaxDbi | P37902 |
PRIDEi | P37902 |
Genome annotation databases
EnsemblBacteriai | AAC73756; AAC73756; b0655 BAA35307; BAA35307; BAA35307 |
GeneIDi | 57728795 946938 |
KEGGi | ecj:JW5092 eco:b0655 |
PATRICi | fig|1411691.4.peg.1613 |
Organism-specific databases
EchoBASEi | EB2562 |
Phylogenomic databases
eggNOGi | COG0834, Bacteria |
HOGENOMi | CLU_019602_0_0_6 |
InParanoidi | P37902 |
PhylomeDBi | P37902 |
Enzyme and pathway databases
BioCyci | EcoCyc:G6359-MONOMER MetaCyc:G6359-MONOMER |
Miscellaneous databases
PROi | PR:P37902 |
Family and domain databases
InterProi | View protein in InterPro IPR001638, Solute-binding_3/MltF_N |
Pfami | View protein in Pfam PF00497, SBP_bac_3, 1 hit |
SMARTi | View protein in SMART SM00062, PBPb, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | GLTI_ECOLI | |
Accessioni | P37902Primary (citable) accession number: P37902 Secondary accession number(s): P41408 Q9R7T3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1994 |
Last sequence update: | November 1, 1997 | |
Last modified: | February 10, 2021 | |
This is version 151 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Direct protein sequencing, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families