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UniProtKB - P37805 (TAGL3_RAT)
Protein
Transgelin-3
Gene
Tagln3
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Biological processi
Names & Taxonomyi
Protein namesi | Recommended name: Transgelin-3Alternative name(s): Neuronal protein 22 Short name: NP22 Neuronal protein NP25 |
Gene namesi | Name:Tagln3 Synonyms:Np25 |
Organismi | Rattus norvegicus (Rat) |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 69301, Tagln3 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000204790 | 1 – 199 | Transgelin-3Add BLAST | 199 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 163 | PhosphoserineCombined sources | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
jPOSTi | P37805 |
PaxDbi | P37805 |
PRIDEi | P37805 |
2D gel databases
World-2DPAGEi | 0004:P37805 |
PTM databases
iPTMneti | P37805 |
PhosphoSitePlusi | P37805 |
SwissPalmi | P37805 |
Expressioni
Tissue specificityi
Abundant and ubiquitous expression in neurons.
Gene expression databases
Bgeei | ENSRNOG00000002151, Expressed in brain and 7 other tissues |
ExpressionAtlasi | P37805, baseline |
Genevisiblei | P37805, RN |
Interactioni
Protein-protein interaction databases
BioGRIDi | 248896, 1 interactor |
STRINGi | 10116.ENSRNOP00000002942 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 24 – 136 | Calponin-homology (CH)PROSITE-ProRule annotationAdd BLAST | 113 | |
Repeati | 174 – 199 | Calponin-likeAdd BLAST | 26 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 178 – 199 | DisorderedSequence analysisAdd BLAST | 22 |
Sequence similaritiesi
Belongs to the calponin family.Curated
Phylogenomic databases
eggNOGi | KOG2046, Eukaryota |
GeneTreei | ENSGT00940000159385 |
HOGENOMi | CLU_055232_1_0_1 |
InParanoidi | P37805 |
OMAi | EYGYMKG |
OrthoDBi | 861989at2759 |
PhylomeDBi | P37805 |
TreeFami | TF313921 |
Family and domain databases
CDDi | cd00014, CH, 1 hit |
Gene3Di | 1.10.418.10, 1 hit |
InterProi | View protein in InterPro IPR000557, Calponin_repeat IPR001715, CH-domain IPR036872, CH_dom_sf IPR003096, SM22_calponin IPR029973, TAGLN3 |
PANTHERi | PTHR18959:SF57, PTHR18959:SF57, 1 hit |
Pfami | View protein in Pfam PF00402, Calponin, 1 hit PF00307, CH, 1 hit |
PRINTSi | PR00888, SM22CALPONIN |
SMARTi | View protein in SMART SM00033, CH, 1 hit |
SUPFAMi | SSF47576, SSF47576, 1 hit |
PROSITEi | View protein in PROSITE PS01052, CALPONIN_1, 1 hit PS51122, CALPONIN_2, 1 hit PS50021, CH, 1 hit |
i Sequence
Sequence statusi: Complete.
P37805-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MANRGPSYGL SREVQEKIEQ KYDADLENKL VDWIILQCAE DIEHPPPGRT
60 70 80 90 100
HFQKWLMDGT VLCKLINSLY PPGQEPIPKI SESKMAFKQM EQISQFLKAA
110 120 130 140 150
EVYGVRTTDI FQTVDLWEGK DMAAVQRTLM ALGSVAVTKD DGCYRGEPSW
160 170 180 190
FHRKAQQNRR GFSEEQLRQG QNVIGLQMGS NKGASQAGMT GYGMPRQIM
Sequence cautioni
The sequence AAC42095 differs from that shown. Reason: Frameshift.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M84725 mRNA Translation: AAC42095.1 Frameshift. AF459788 mRNA Translation: AAL66341.1 |
PIRi | I52644 |
RefSeqi | NP_001030313.1, NM_001035236.1 NP_113864.2, NM_031676.2 XP_008766898.1, XM_008768676.1 |
Genome annotation databases
Ensembli | ENSRNOT00000090230; ENSRNOP00000072985; ENSRNOG00000064186 |
GeneIDi | 63837 |
KEGGi | rno:63837 |
UCSCi | RGD:69301, rat |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M84725 mRNA Translation: AAC42095.1 Frameshift. AF459788 mRNA Translation: AAL66341.1 |
PIRi | I52644 |
RefSeqi | NP_001030313.1, NM_001035236.1 NP_113864.2, NM_031676.2 XP_008766898.1, XM_008768676.1 |
3D structure databases
AlphaFoldDBi | P37805 |
SMRi | P37805 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 248896, 1 interactor |
STRINGi | 10116.ENSRNOP00000002942 |
PTM databases
iPTMneti | P37805 |
PhosphoSitePlusi | P37805 |
SwissPalmi | P37805 |
2D gel databases
World-2DPAGEi | 0004:P37805 |
Proteomic databases
jPOSTi | P37805 |
PaxDbi | P37805 |
PRIDEi | P37805 |
Genome annotation databases
Ensembli | ENSRNOT00000090230; ENSRNOP00000072985; ENSRNOG00000064186 |
GeneIDi | 63837 |
KEGGi | rno:63837 |
UCSCi | RGD:69301, rat |
Organism-specific databases
CTDi | 29114 |
RGDi | 69301, Tagln3 |
Phylogenomic databases
eggNOGi | KOG2046, Eukaryota |
GeneTreei | ENSGT00940000159385 |
HOGENOMi | CLU_055232_1_0_1 |
InParanoidi | P37805 |
OMAi | EYGYMKG |
OrthoDBi | 861989at2759 |
PhylomeDBi | P37805 |
TreeFami | TF313921 |
Miscellaneous databases
PROi | PR:P37805 |
Gene expression databases
Bgeei | ENSRNOG00000002151, Expressed in brain and 7 other tissues |
ExpressionAtlasi | P37805, baseline |
Genevisiblei | P37805, RN |
Family and domain databases
CDDi | cd00014, CH, 1 hit |
Gene3Di | 1.10.418.10, 1 hit |
InterProi | View protein in InterPro IPR000557, Calponin_repeat IPR001715, CH-domain IPR036872, CH_dom_sf IPR003096, SM22_calponin IPR029973, TAGLN3 |
PANTHERi | PTHR18959:SF57, PTHR18959:SF57, 1 hit |
Pfami | View protein in Pfam PF00402, Calponin, 1 hit PF00307, CH, 1 hit |
PRINTSi | PR00888, SM22CALPONIN |
SMARTi | View protein in SMART SM00033, CH, 1 hit |
SUPFAMi | SSF47576, SSF47576, 1 hit |
PROSITEi | View protein in PROSITE PS01052, CALPONIN_1, 1 hit PS51122, CALPONIN_2, 1 hit PS50021, CH, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | TAGL3_RAT | |
Accessioni | P37805Primary (citable) accession number: P37805 Secondary accession number(s): Q09025, Q8VHH3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1994 |
Last sequence update: | January 23, 2007 | |
Last modified: | May 25, 2022 | |
This is version 146 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Direct protein sequencing, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families