UniProtKB - P37679 (SGBU_ECOLI)
Protein
Putative L-ribulose-5-phosphate 3-epimerase SgbU
Gene
sgbU
Organism
Escherichia coli (strain K12)
Status
Functioni
Catalyzes the isomerization of L-xylulose-5-phosphate to L-ribulose-5-phosphate (Potential). May be involved in the utilization of 2,3-diketo-L-gulonate.Curated
Catalytic activityi
- EC:5.1.3.22
GO - Molecular functioni
- DNA binding Source: InterPro
- intramolecular oxidoreductase activity, interconverting aldoses and ketoses Source: InterPro
- L-ribulose-5-phosphate 3-epimerase activity Source: EcoCyc
- zinc ion binding Source: InterPro
GO - Biological processi
- DNA repair Source: InterPro
- L-ascorbic acid metabolic process Source: GO_Central
- L-lyxose metabolic process Source: EcoCyc
Keywordsi
Molecular function | Isomerase |
Biological process | Carbohydrate metabolism |
Enzyme and pathway databases
BioCyci | EcoCyc:EG12286-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Putative L-ribulose-5-phosphate 3-epimerase SgbU (EC:5.1.3.22)Alternative name(s): L-xylulose-5-phosphate 3-epimerase |
Gene namesi | Name:sgbU Synonyms:yiaR Ordered Locus Names:b3582, JW5650 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000097718 | 1 – 286 | Putative L-ribulose-5-phosphate 3-epimerase SgbUAdd BLAST | 286 |
Proteomic databases
PaxDbi | P37679 |
PRIDEi | P37679 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4259345, 3 interactors |
STRINGi | 511145.b3582 |
Family & Domainsi
Sequence similaritiesi
Belongs to the L-ribulose-5-phosphate 3-epimerase family.Curated
Phylogenomic databases
eggNOGi | COG3623, Bacteria |
HOGENOMi | CLU_082738_0_0_6 |
InParanoidi | P37679 |
PhylomeDBi | P37679 |
Family and domain databases
CDDi | cd00019, AP2Ec, 1 hit |
InterProi | View protein in InterPro IPR001719, AP_endonuc_2 IPR004560, L-Ru-5P_3-Epase IPR036237, Xyl_isomerase-like_sf IPR013022, Xyl_isomerase-like_TIM-brl |
Pfami | View protein in Pfam PF01261, AP_endonuc_2, 1 hit |
SUPFAMi | SSF51658, SSF51658, 1 hit |
TIGRFAMsi | TIGR00542, hxl6Piso_put, 1 hit |
i Sequence
Sequence statusi: Complete.
P37679-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRNHQLGIYE KALAKDLSWP ERLVLAKSCG FDFVEMSVDE TDERLSRLDW
60 70 80 90 100
SAAQRTSLVA AMIETGVGIP SMCLSAHRRF PFGSRDEAVR ERAREIMSKA
110 120 130 140 150
IRLARDLGIR TIQLAGYDVY YEDHDEGTRQ RFAEGLAWAV EQAAASQVML
160 170 180 190 200
AVEIMDTAFM NSISKWKKWD EMLASPWFTV YPDVGNLSAW GNDVPAELKL
210 220 230 240 250
GIDRIAAIHL KDTQPVTGQS PGQFRDVPFG EGCVDFVGIF KTLHKLNYRG
260 270 280
SFLIEMWTEK AKEPVLEIIQ ARRWIEARMQ EAGFIC
Sequence cautioni
The sequence AAB18559 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00039 Genomic DNA Translation: AAB18559.1 Different initiation. U00096 Genomic DNA Translation: AAC76606.2 AP009048 Genomic DNA Translation: BAE77711.1 |
PIRi | S47803 |
RefSeqi | NP_418039.2, NC_000913.3 WP_001350555.1, NZ_LN832404.1 |
Genome annotation databases
EnsemblBacteriai | AAC76606; AAC76606; b3582 BAE77711; BAE77711; BAE77711 |
GeneIDi | 948100 |
KEGGi | ecj:JW5650 eco:b3582 |
PATRICi | fig|511145.12.peg.3697 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00039 Genomic DNA Translation: AAB18559.1 Different initiation. U00096 Genomic DNA Translation: AAC76606.2 AP009048 Genomic DNA Translation: BAE77711.1 |
PIRi | S47803 |
RefSeqi | NP_418039.2, NC_000913.3 WP_001350555.1, NZ_LN832404.1 |
3D structure databases
SMRi | P37679 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4259345, 3 interactors |
STRINGi | 511145.b3582 |
Proteomic databases
PaxDbi | P37679 |
PRIDEi | P37679 |
Genome annotation databases
EnsemblBacteriai | AAC76606; AAC76606; b3582 BAE77711; BAE77711; BAE77711 |
GeneIDi | 948100 |
KEGGi | ecj:JW5650 eco:b3582 |
PATRICi | fig|511145.12.peg.3697 |
Organism-specific databases
EchoBASEi | EB2194 |
Phylogenomic databases
eggNOGi | COG3623, Bacteria |
HOGENOMi | CLU_082738_0_0_6 |
InParanoidi | P37679 |
PhylomeDBi | P37679 |
Enzyme and pathway databases
BioCyci | EcoCyc:EG12286-MONOMER |
Miscellaneous databases
PROi | PR:P37679 |
Family and domain databases
CDDi | cd00019, AP2Ec, 1 hit |
InterProi | View protein in InterPro IPR001719, AP_endonuc_2 IPR004560, L-Ru-5P_3-Epase IPR036237, Xyl_isomerase-like_sf IPR013022, Xyl_isomerase-like_TIM-brl |
Pfami | View protein in Pfam PF01261, AP_endonuc_2, 1 hit |
SUPFAMi | SSF51658, SSF51658, 1 hit |
TIGRFAMsi | TIGR00542, hxl6Piso_put, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | SGBU_ECOLI | |
Accessioni | P37679Primary (citable) accession number: P37679 Secondary accession number(s): Q2M7P5 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1994 |
Last sequence update: | July 15, 1999 | |
Last modified: | December 2, 2020 | |
This is version 138 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families