UniProtKB - P37643 (YHJE_ECOLI)
Protein
Inner membrane metabolite transport protein YhjE
Gene
yhjE
Organism
Escherichia coli (strain K12)
Status
Functioni
GO - Molecular functioni
- transmembrane transporter activity Source: InterPro
Keywordsi
Biological process | Transport |
Enzyme and pathway databases
BioCyci | EcoCyc:YHJE-MONOMER |
Protein family/group databases
TCDBi | 2.A.1.6.10, the major facilitator superfamily (mfs) |
Names & Taxonomyi
Protein namesi | Recommended name: Inner membrane metabolite transport protein YhjE |
Gene namesi | Name:yhjE Ordered Locus Names:b3523, JW3491 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
Plasma Membrane
- plasma membrane Source: EcoCyc
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 34 | CytoplasmicSequence analysisAdd BLAST | 34 | |
Transmembranei | 35 – 55 | Helical; Name=1Sequence analysisAdd BLAST | 21 | |
Topological domaini | 56 – 66 | PeriplasmicSequence analysisAdd BLAST | 11 | |
Transmembranei | 67 – 87 | Helical; Name=2Sequence analysisAdd BLAST | 21 | |
Topological domaini | 88 – 108 | CytoplasmicSequence analysisAdd BLAST | 21 | |
Transmembranei | 109 – 129 | Helical; Name=3Sequence analysisAdd BLAST | 21 | |
Transmembranei | 130 – 150 | Helical; Name=4Sequence analysisAdd BLAST | 21 | |
Topological domaini | 151 – 167 | CytoplasmicSequence analysisAdd BLAST | 17 | |
Transmembranei | 168 – 188 | Helical; Name=5Sequence analysisAdd BLAST | 21 | |
Topological domaini | 189 – 192 | PeriplasmicSequence analysis | 4 | |
Transmembranei | 193 – 213 | Helical; Name=6Sequence analysisAdd BLAST | 21 | |
Topological domaini | 214 – 248 | CytoplasmicSequence analysisAdd BLAST | 35 | |
Transmembranei | 249 – 269 | Helical; Name=7Sequence analysisAdd BLAST | 21 | |
Topological domaini | 270 – 289 | PeriplasmicSequence analysisAdd BLAST | 20 | |
Transmembranei | 290 – 310 | Helical; Name=8Sequence analysisAdd BLAST | 21 | |
Topological domaini | 311 – 320 | CytoplasmicSequence analysis | 10 | |
Transmembranei | 321 – 341 | Helical; Name=9Sequence analysisAdd BLAST | 21 | |
Topological domaini | 342 – 345 | PeriplasmicSequence analysis | 4 | |
Transmembranei | 346 – 366 | Helical; Name=10Sequence analysisAdd BLAST | 21 | |
Topological domaini | 367 – 384 | CytoplasmicSequence analysisAdd BLAST | 18 | |
Transmembranei | 385 – 405 | Helical; Name=11Sequence analysisAdd BLAST | 21 | |
Topological domaini | 406 – 410 | PeriplasmicSequence analysis | 5 | |
Transmembranei | 411 – 431 | Helical; Name=12Sequence analysisAdd BLAST | 21 | |
Topological domaini | 432 – 440 | CytoplasmicSequence analysis | 9 |
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000050486 | 1 – 440 | Inner membrane metabolite transport protein YhjEAdd BLAST | 440 |
Proteomic databases
PaxDbi | P37643 |
PRIDEi | P37643 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4262156, 334 interactors |
STRINGi | 511145.b3523 |
Family & Domainsi
Sequence similaritiesi
Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family. [View classification]Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG0477, Bacteria |
HOGENOMi | CLU_001265_39_5_6 |
InParanoidi | P37643 |
PhylomeDBi | P37643 |
Family and domain databases
InterProi | View protein in InterPro IPR011701, MFS IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR004736, MHS_symport IPR005829, Sugar_transporter_CS |
Pfami | View protein in Pfam PF07690, MFS_1, 1 hit PF00083, Sugar_tr, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00883, 2A0106, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00216, SUGAR_TRANSPORT_1, 1 hit |
i Sequence
Sequence statusi: Complete.
P37643-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MQATATTLDH EQEYTPINSR NKVLVASLIG TAIEFFDFYI YATAAVIVFP
60 70 80 90 100
HIFFPQGDPT AATLQSLATF AIAFVARPIG SAVFGHFGDR VGRKATLVAS
110 120 130 140 150
LLTMGISTVV IGLLPGYATI GIFAPLLLAL ARFGQGLGLG GEWGGAALLA
160 170 180 190 200
TENAPPRKRA LYGSFPQLGA PIGFFFANGT FLLLSWLLTD EQFMSWGWRV
210 220 230 240 250
PFIFSAVLVI IGLYVRVSLH ESPVFEKVAK AKKQVKIPLG TLLTKHVRVT
260 270 280 290 300
VLGTFIMLAT YTLFYIMTVY SMTFSTAAAP VGLGLPRNEV LWMLMMAVIG
310 320 330 340 350
FGVMVPVAGL LADAFGRRKS MVIITTLIIL FALFAFNPLL GSGNPILVFA
360 370 380 390 400
FLLLGLSLMG LTFGPMGALL PELFPTEVRY TGASFSYNVA SILGASVAPY
410 420 430 440
IAAWLQTNYG LGAVGLYLAA MAGLTLIALL LTHETRHQSL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00039 Genomic DNA Translation: AAB18499.1 U00096 Genomic DNA Translation: AAC76548.1 AP009048 Genomic DNA Translation: BAE77771.1 |
PIRi | S47743 |
RefSeqi | NP_417980.1, NC_000913.3 WP_001149003.1, NZ_SSZK01000039.1 |
Genome annotation databases
EnsemblBacteriai | AAC76548; AAC76548; b3523 BAE77771; BAE77771; BAE77771 |
GeneIDi | 57729219 948032 |
KEGGi | ecj:JW3491 eco:b3523 |
PATRICi | fig|1411691.4.peg.3195 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00039 Genomic DNA Translation: AAB18499.1 U00096 Genomic DNA Translation: AAC76548.1 AP009048 Genomic DNA Translation: BAE77771.1 |
PIRi | S47743 |
RefSeqi | NP_417980.1, NC_000913.3 WP_001149003.1, NZ_SSZK01000039.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 4262156, 334 interactors |
STRINGi | 511145.b3523 |
Protein family/group databases
TCDBi | 2.A.1.6.10, the major facilitator superfamily (mfs) |
Proteomic databases
PaxDbi | P37643 |
PRIDEi | P37643 |
Genome annotation databases
EnsemblBacteriai | AAC76548; AAC76548; b3523 BAE77771; BAE77771; BAE77771 |
GeneIDi | 57729219 948032 |
KEGGi | ecj:JW3491 eco:b3523 |
PATRICi | fig|1411691.4.peg.3195 |
Organism-specific databases
EchoBASEi | EB2160 |
Phylogenomic databases
eggNOGi | COG0477, Bacteria |
HOGENOMi | CLU_001265_39_5_6 |
InParanoidi | P37643 |
PhylomeDBi | P37643 |
Enzyme and pathway databases
BioCyci | EcoCyc:YHJE-MONOMER |
Miscellaneous databases
PROi | PR:P37643 |
Family and domain databases
InterProi | View protein in InterPro IPR011701, MFS IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR004736, MHS_symport IPR005829, Sugar_transporter_CS |
Pfami | View protein in Pfam PF07690, MFS_1, 1 hit PF00083, Sugar_tr, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00883, 2A0106, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00216, SUGAR_TRANSPORT_1, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | YHJE_ECOLI | |
Accessioni | P37643Primary (citable) accession number: P37643 Secondary accession number(s): Q2M7I5 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1994 |
Last sequence update: | October 1, 1994 | |
Last modified: | February 10, 2021 | |
This is version 147 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families