UniProtKB - P37443 (YCAI_ECOLI)
Protein
Uncharacterized protein YcaI
Gene
ycaI
Organism
Escherichia coli (strain K12)
Status
Functioni
GO - Biological processi
- establishment of competence for transformation Source: InterPro
Enzyme and pathway databases
BioCyci | EcoCyc:EG12375-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Uncharacterized protein YcaI |
Gene namesi | Name:ycaI Ordered Locus Names:b0913, JW5120 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
- Cell membrane Curated; Multi-pass membrane protein Curated
Plasma Membrane
- plasma membrane Source: EcoCyc
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 3 – 23 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 24 – 44 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 50 – 70 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 223 – 243 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 254 – 274 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 320 – 340 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 370 – 390 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 392 – 412 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 446 – 466 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 471 – 491 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000168754 | 1 – 754 | Uncharacterized protein YcaIAdd BLAST | 754 |
Proteomic databases
PaxDbi | P37443 |
PRIDEi | P37443 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4261065, 133 interactors |
STRINGi | 511145.b0913 |
Family & Domainsi
Sequence similaritiesi
To B.subtilis ComEC, N.gonorrhoeae ComA, and H.influenzae Rec2.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG0658, Bacteria COG2333, Bacteria |
HOGENOMi | CLU_010363_3_0_6 |
InParanoidi | P37443 |
PhylomeDBi | P37443 |
Family and domain databases
CDDi | cd07731, ComA-like_MBL-fold, 1 hit |
Gene3Di | 3.60.15.10, 1 hit |
InterProi | View protein in InterPro IPR035681, ComA-like_MBL IPR004477, ComEC_N IPR004797, Competence_ComEC/Rec2 IPR001279, Metallo-B-lactamas IPR036866, RibonucZ/Hydroxyglut_hydro |
Pfami | View protein in Pfam PF03772, Competence, 1 hit PF00753, Lactamase_B, 1 hit |
SMARTi | View protein in SMART SM00849, Lactamase_B, 1 hit |
SUPFAMi | SSF56281, SSF56281, 1 hit |
TIGRFAMsi | TIGR00360, ComEC_N-term, 1 hit TIGR00361, ComEC_Rec2, 1 hit |
i Sequence
Sequence statusi: Complete.
P37443-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKITTVGVCI ISGIFPLLIL PQLPGTLTLA FLTLFACVLA FIPVKTVRYI
60 70 80 90 100
ALTLLFFVWG ILSAKQILWA GETLTGATQD AIVEITATDG MTTHYGQITH
110 120 130 140 150
LQGRRIFPAS GLVMYGEYLP QAVCAGQQWS MKLKVRAVHG QLNDGGFDSQ
160 170 180 190 200
RYAIAQHQPL TGRFLQASVI EPNCSLRAQY LASLQTTLQP YPWNAVILGL
210 220 230 240 250
GMGERLSVPK EIKNIMRDTG TAHLMAISGL HIAFAALLAA GLIRSGQIFL
260 270 280 290 300
PGRWIHWQIP LIGGICCAAF YAWLTGMQPP ALRTMVALAT WGMLKLSGRQ
310 320 330 340 350
WSGWDVWICC LAAILLMDPV AILSQSLWLS AAAVAALIFW YQWFPCPEWQ
360 370 380 390 400
LPPVLRAVVS LIHLQLGITL LLMPVQIVIF HGISLTSFIA NLLAIPLVTF
410 420 430 440 450
ITVPLILAAM VVHLSGPLIL EQGLWFLADR SLALLFWGLK SLPEGWINIA
460 470 480 490 500
ECWQWLSFSP WFLLVVWRLN AWRTLPAMCV AGGLLMCWPL WQKPRPDEWQ
510 520 530 540 550
LYMLDVGQGL AMVIARNGKA ILYDTGLAWP EGDSGQQLII PWLHWHNLEP
560 570 580 590 600
EGVILSHEHL DHRGGLDSIL HIWPMLWIRS PLNWEHHQPC VRGEAWQWQG
610 620 630 640 650
LRFSAHWPLQ GSNDKGNNHS CVVKVDDGTN SILLTGDIEA PAEQKMLSRY
660 670 680 690 700
WQQVQATLLQ VPHHGSNTSS SLPLIQRVNG KVALASASRY NAWRLPSNKV
710 720 730 740 750
KHRYQLQGYQ WIDTPHQGQT TVNFSAQGWR ISSLREQILP RWYHQWFGVP
VDNG
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 581 – 595 | PLNWE…VRGEA → SVKLGTSSALCAWRT in Z11796 (PubMed:8094880).CuratedAdd BLAST | 15 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC73999.2 AP009048 Genomic DNA Translation: BAA35657.2 Z11796 Genomic DNA No translation available. |
PIRi | H64830 |
RefSeqi | NP_415433.4, NC_000913.3 WP_000705764.1, NZ_SSZK01000002.1 |
Genome annotation databases
EnsemblBacteriai | AAC73999; AAC73999; b0913 BAA35657; BAA35657; BAA35657 |
GeneIDi | 57728324 945531 |
KEGGi | ecj:JW5120 eco:b0913 |
PATRICi | fig|1411691.4.peg.1363 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC73999.2 AP009048 Genomic DNA Translation: BAA35657.2 Z11796 Genomic DNA No translation available. |
PIRi | H64830 |
RefSeqi | NP_415433.4, NC_000913.3 WP_000705764.1, NZ_SSZK01000002.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 4261065, 133 interactors |
STRINGi | 511145.b0913 |
Proteomic databases
PaxDbi | P37443 |
PRIDEi | P37443 |
Genome annotation databases
EnsemblBacteriai | AAC73999; AAC73999; b0913 BAA35657; BAA35657; BAA35657 |
GeneIDi | 57728324 945531 |
KEGGi | ecj:JW5120 eco:b0913 |
PATRICi | fig|1411691.4.peg.1363 |
Organism-specific databases
EchoBASEi | EB2278 |
Phylogenomic databases
eggNOGi | COG0658, Bacteria COG2333, Bacteria |
HOGENOMi | CLU_010363_3_0_6 |
InParanoidi | P37443 |
PhylomeDBi | P37443 |
Enzyme and pathway databases
BioCyci | EcoCyc:EG12375-MONOMER |
Miscellaneous databases
PROi | PR:P37443 |
Family and domain databases
CDDi | cd07731, ComA-like_MBL-fold, 1 hit |
Gene3Di | 3.60.15.10, 1 hit |
InterProi | View protein in InterPro IPR035681, ComA-like_MBL IPR004477, ComEC_N IPR004797, Competence_ComEC/Rec2 IPR001279, Metallo-B-lactamas IPR036866, RibonucZ/Hydroxyglut_hydro |
Pfami | View protein in Pfam PF03772, Competence, 1 hit PF00753, Lactamase_B, 1 hit |
SMARTi | View protein in SMART SM00849, Lactamase_B, 1 hit |
SUPFAMi | SSF56281, SSF56281, 1 hit |
TIGRFAMsi | TIGR00360, ComEC_N-term, 1 hit TIGR00361, ComEC_Rec2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | YCAI_ECOLI | |
Accessioni | P37443Primary (citable) accession number: P37443 Secondary accession number(s): P75841 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1994 |
Last sequence update: | April 27, 2001 | |
Last modified: | February 10, 2021 | |
This is version 148 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |