UniProtKB - P37388 (XYLG_ECOLI)
Protein
Xylose import ATP-binding protein XylG
Gene
xylG
Organism
Escherichia coli (strain K12)
Status
Functioni
Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system (Probable). The XylFGH system can also transport ribose in absence of xylose.UniRule annotationCurated1 Publication
Catalytic activityi
- EC:7.5.2.10UniRule annotation
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 37 – 44 | ATPUniRule annotation | 8 |
GO - Molecular functioni
- ABC-type D-xylose transporter activity Source: UniProtKB-UniRule
- ATPase activity Source: InterPro
- ATP binding Source: EcoCyc
- D-xylose transmembrane transporter activity Source: EcoCyc
GO - Biological processi
- D-xylose metabolic process Source: EcoCyc
- D-xylose transmembrane transport Source: EcoCyc
Keywordsi
Molecular function | Translocase |
Biological process | Sugar transport, Transport |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
BioCyci | EcoCyc:XYLG-MONOMER MetaCyc:XYLG-MONOMER |
Protein family/group databases
TCDBi | 3.A.1.2.4, the atp-binding cassette (abc) superfamily |
Names & Taxonomyi
Protein namesi | Recommended name: Xylose import ATP-binding protein XylGUniRule annotation (EC:7.5.2.10UniRule annotation) |
Gene namesi | Name:xylGUniRule annotation Ordered Locus Names:b3567, JW3539 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
- Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000093124 | 1 – 513 | Xylose import ATP-binding protein XylGAdd BLAST | 513 |
Proteomic databases
PaxDbi | P37388 |
PRIDEi | P37388 |
Interactioni
Subunit structurei
The complex is composed of two ATP-binding proteins (XylG), two transmembrane proteins (XylH) and a solute-binding protein (XylF).
UniRule annotationProtein-protein interaction databases
BioGRIDi | 4262542, 7 interactors 852434, 1 interactor |
ComplexPortali | CPX-4388, Xylose ABC transporter complex |
IntActi | P37388, 7 interactors |
STRINGi | 511145.b3567 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 5 – 242 | ABC transporter 1UniRule annotationAdd BLAST | 238 | |
Domaini | 259 – 505 | ABC transporter 2UniRule annotationAdd BLAST | 247 |
Sequence similaritiesi
Belongs to the ABC transporter superfamily. Xylose importer (TC 3.A.1.2.4) family. [View classification]UniRule annotation
Keywords - Domaini
RepeatPhylogenomic databases
eggNOGi | COG1129, Bacteria |
HOGENOMi | CLU_000604_92_3_6 |
InParanoidi | P37388 |
PhylomeDBi | P37388 |
Family and domain databases
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR003439, ABC_transporter-like IPR017871, ABC_transporter_CS IPR013455, ABC_transptr_xylose_ATP-bd IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00005, ABC_tran, 2 hits |
SMARTi | View protein in SMART SM00382, AAA, 2 hits |
SUPFAMi | SSF52540, SSF52540, 2 hits |
TIGRFAMsi | TIGR02633, xylG, 1 hit |
PROSITEi | View protein in PROSITE PS00211, ABC_TRANSPORTER_1, 1 hit PS50893, ABC_TRANSPORTER_2, 2 hits PS51280, XYLG, 1 hit |
i Sequence
Sequence statusi: Complete.
P37388-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPYLLEMKNI TKTFGSVKAI DNVCLRLNAG EIVSLCGENG SGKSTLMKVL
60 70 80 90 100
CGIYPHGSYE GEIIFAGEEI QASHIRDTER KGIAIIHQEL ALVKELTVLE
110 120 130 140 150
NIFLGNEITH NGIMDYDLMT LRCQKLLAQV SLSISPDTRV GDLGLGQQQL
160 170 180 190 200
VEIAKALNKQ VRLLILDEPT ASLTEQETSI LLDIIRDLQQ HGIACIYISH
210 220 230 240 250
KLNEVKAISD TICVIRDGQH IGTRDAAGMS EDDIITMMVG RELTALYPNE
260 270 280 290 300
PHTTGDEILR IEHLTAWHPV NRHIKRVNDV SFSLKRGEIL GIAGLVGAGR
310 320 330 340 350
TETIQCLFGV WPGQWEGKIY IDGKQVDIRN CQQAIAQGIA MVPEDRKRDG
360 370 380 390 400
IVPVMAVGKN ITLAALNKFT GGISQLDDAA EQKCILESIQ QLKVKTSSPD
410 420 430 440 450
LAIGRLSGGN QQKAILARCL LLNPRILILD EPTRGIDIGA KYEIYKLINQ
460 470 480 490 500
LVQQGIAVIV ISSELPEVLG LSDRVLVMHE GKLKANLINH NLTQEQVMEA
510
ALRSEHHVEK QSV
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00039 Genomic DNA Translation: AAB18544.1 U00096 Genomic DNA Translation: AAC76591.1 AP009048 Genomic DNA Translation: BAE77726.1 |
PIRi | S47788 |
RefSeqi | NP_418024.1, NC_000913.3 WP_001146473.1, NZ_LN832404.1 |
Genome annotation databases
EnsemblBacteriai | AAC76591; AAC76591; b3567 BAE77726; BAE77726; BAE77726 |
GeneIDi | 948127 |
KEGGi | ecj:JW3539 eco:b3567 |
PATRICi | fig|1411691.4.peg.3145 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00039 Genomic DNA Translation: AAB18544.1 U00096 Genomic DNA Translation: AAC76591.1 AP009048 Genomic DNA Translation: BAE77726.1 |
PIRi | S47788 |
RefSeqi | NP_418024.1, NC_000913.3 WP_001146473.1, NZ_LN832404.1 |
3D structure databases
SMRi | P37388 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4262542, 7 interactors 852434, 1 interactor |
ComplexPortali | CPX-4388, Xylose ABC transporter complex |
IntActi | P37388, 7 interactors |
STRINGi | 511145.b3567 |
Protein family/group databases
TCDBi | 3.A.1.2.4, the atp-binding cassette (abc) superfamily |
Proteomic databases
PaxDbi | P37388 |
PRIDEi | P37388 |
Genome annotation databases
EnsemblBacteriai | AAC76591; AAC76591; b3567 BAE77726; BAE77726; BAE77726 |
GeneIDi | 948127 |
KEGGi | ecj:JW3539 eco:b3567 |
PATRICi | fig|1411691.4.peg.3145 |
Organism-specific databases
EchoBASEi | EB2184 |
Phylogenomic databases
eggNOGi | COG1129, Bacteria |
HOGENOMi | CLU_000604_92_3_6 |
InParanoidi | P37388 |
PhylomeDBi | P37388 |
Enzyme and pathway databases
BioCyci | EcoCyc:XYLG-MONOMER MetaCyc:XYLG-MONOMER |
Miscellaneous databases
PROi | PR:P37388 |
Family and domain databases
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR003439, ABC_transporter-like IPR017871, ABC_transporter_CS IPR013455, ABC_transptr_xylose_ATP-bd IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00005, ABC_tran, 2 hits |
SMARTi | View protein in SMART SM00382, AAA, 2 hits |
SUPFAMi | SSF52540, SSF52540, 2 hits |
TIGRFAMsi | TIGR02633, xylG, 1 hit |
PROSITEi | View protein in PROSITE PS00211, ABC_TRANSPORTER_1, 1 hit PS50893, ABC_TRANSPORTER_2, 2 hits PS51280, XYLG, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | XYLG_ECOLI | |
Accessioni | P37388Primary (citable) accession number: P37388 Secondary accession number(s): Q2M7N0 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1994 |
Last sequence update: | October 1, 1994 | |
Last modified: | April 7, 2021 | |
This is version 160 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families