UniProtKB - P37387 (XYLF_ECOLI)
Protein
D-xylose-binding periplasmic protein
Gene
xylF
Organism
Escherichia coli (strain K12)
Status
Functioni
Involved in the high-affinity D-xylose membrane transport system. Binds with high affinity to xylose.
Miscellaneous
E.coli has two D-xylose transport systems that accumulate sugar against a concentration gradient: the XylE system which utilizes the electrochemical gradient of protons and that is insensitive to cold osmotic shock and the XylF system that uses a high-energy phosphate compound and is sensitive to cold osmotic shock.
GO - Molecular functioni
- carbohydrate binding Source: GO_Central
- monosaccharide binding Source: EcoCyc
GO - Biological processi
- D-xylose metabolic process Source: EcoCyc
- D-xylose transmembrane transport Source: EcoCyc
Keywordsi
Biological process | Sugar transport, Transport |
Enzyme and pathway databases
BioCyci | EcoCyc:XYLF-MONOMER MetaCyc:XYLF-MONOMER |
Protein family/group databases
TCDBi | 3.A.1.2.4, the atp-binding cassette (abc) superfamily |
Names & Taxonomyi
Protein namesi | Recommended name: D-xylose-binding periplasmic protein |
Gene namesi | Name:xylF Synonyms:xylT Ordered Locus Names:b3566, JW3538 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
GO - Cellular componenti
- outer membrane-bounded periplasmic space Source: EcoCyc
Keywords - Cellular componenti
PeriplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 23 | 3 PublicationsAdd BLAST | 23 | |
ChainiPRO_0000031738 | 24 – 330 | D-xylose-binding periplasmic proteinAdd BLAST | 307 |
Proteomic databases
jPOSTi | P37387 |
PaxDbi | P37387 |
PRIDEi | P37387 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4262541, 29 interactors 852398, 1 interactor |
ComplexPortali | CPX-4388, Xylose ABC transporter complex |
IntActi | P37387, 4 interactors |
STRINGi | 511145.b3566 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P37387 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P37387 |
Family & Domainsi
Sequence similaritiesi
Belongs to the bacterial solute-binding protein 2 family.Curated
Keywords - Domaini
SignalPhylogenomic databases
eggNOGi | COG4213, Bacteria |
HOGENOMi | CLU_037628_13_0_6 |
InParanoidi | P37387 |
PhylomeDBi | P37387 |
Family and domain databases
InterProi | View protein in InterPro IPR028082, Peripla_BP_I IPR025997, SBP_2_dom IPR013456, XylF |
Pfami | View protein in Pfam PF13407, Peripla_BP_4, 1 hit |
SUPFAMi | SSF53822, SSF53822, 1 hit |
TIGRFAMsi | TIGR02634, xylF, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P37387-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKIKNILLTL CTSLLLTNVA AHAKEVKIGM AIDDLRLERW QKDRDIFVKK
60 70 80 90 100
AESLGAKVFV QSANGNEETQ MSQIENMINR GVDVLVIIPY NGQVLSNVVK
110 120 130 140 150
EAKQEGIKVL AYDRMINDAD IDFYISFDNE KVGELQAKAL VDIVPQGNYF
160 170 180 190 200
LMGGSPVDNN AKLFRAGQMK VLKPYVDSGK IKVVGDQWVD GWLPENALKI
210 220 230 240 250
MENALTANNN KIDAVVASND ATAGGAIQAL SAQGLSGKVA ISGQDADLAG
260 270 280 290 300
IKRIAAGTQT MTVYKPITLL ANTAAEIAVE LGNGQEPKAD TTLNNGLKDV
310 320 330
PSRLLTPIDV NKNNIKDTVI KDGFHKESEL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00039 Genomic DNA Translation: AAB18543.1 U00096 Genomic DNA Translation: AAC76590.1 AP009048 Genomic DNA Translation: BAE77727.1 |
PIRi | S47787 |
RefSeqi | NP_418023.1, NC_000913.3 WP_000694881.1, NZ_SSZK01000041.1 |
Genome annotation databases
EnsemblBacteriai | AAC76590; AAC76590; b3566 BAE77727; BAE77727; BAE77727 |
GeneIDi | 52074860 948090 |
KEGGi | ecj:JW3538 eco:b3566 |
PATRICi | fig|1411691.4.peg.3146 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00039 Genomic DNA Translation: AAB18543.1 U00096 Genomic DNA Translation: AAC76590.1 AP009048 Genomic DNA Translation: BAE77727.1 |
PIRi | S47787 |
RefSeqi | NP_418023.1, NC_000913.3 WP_000694881.1, NZ_SSZK01000041.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
3M9W | X-ray | 2.15 | A | 24-330 | [»] | |
3M9X | X-ray | 2.20 | A | 24-330 | [»] | |
3MA0 | X-ray | 2.20 | A/B/C | 24-330 | [»] | |
SMRi | P37387 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 4262541, 29 interactors 852398, 1 interactor |
ComplexPortali | CPX-4388, Xylose ABC transporter complex |
IntActi | P37387, 4 interactors |
STRINGi | 511145.b3566 |
Protein family/group databases
TCDBi | 3.A.1.2.4, the atp-binding cassette (abc) superfamily |
Proteomic databases
jPOSTi | P37387 |
PaxDbi | P37387 |
PRIDEi | P37387 |
Genome annotation databases
EnsemblBacteriai | AAC76590; AAC76590; b3566 BAE77727; BAE77727; BAE77727 |
GeneIDi | 52074860 948090 |
KEGGi | ecj:JW3538 eco:b3566 |
PATRICi | fig|1411691.4.peg.3146 |
Organism-specific databases
EchoBASEi | EB4153 |
Phylogenomic databases
eggNOGi | COG4213, Bacteria |
HOGENOMi | CLU_037628_13_0_6 |
InParanoidi | P37387 |
PhylomeDBi | P37387 |
Enzyme and pathway databases
BioCyci | EcoCyc:XYLF-MONOMER MetaCyc:XYLF-MONOMER |
Miscellaneous databases
EvolutionaryTracei | P37387 |
PROi | PR:P37387 |
Family and domain databases
InterProi | View protein in InterPro IPR028082, Peripla_BP_I IPR025997, SBP_2_dom IPR013456, XylF |
Pfami | View protein in Pfam PF13407, Peripla_BP_4, 1 hit |
SUPFAMi | SSF53822, SSF53822, 1 hit |
TIGRFAMsi | TIGR02634, xylF, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | XYLF_ECOLI | |
Accessioni | P37387Primary (citable) accession number: P37387 Secondary accession number(s): Q2M7M9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1994 |
Last sequence update: | October 1, 1994 | |
Last modified: | December 2, 2020 | |
This is version 149 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families