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Entry version 174 (10 Feb 2021)
Sequence version 2 (01 Oct 1996)
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Protein

6-phosphogluconolactonase-like protein 2

Gene

SOL2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in regulation of tRNA subcellular distribution.1 Publication

Miscellaneous

Present with 1160 molecules/cell in log phase SD medium.1 Publication

Caution

Lacks 6-phosphogluconolactonase activity.Curated

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
6-phosphogluconolactonase-like protein 2
Alternative name(s):
Suppressor of LOS1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SOL2
Ordered Locus Names:YCR073W-A
ORF Names:YCRX13W
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559292 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome III

Organism-specific databases

Saccharomyces Genome Database

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SGDi
S000000718, SOL2

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
FungiDB:YCR073W-A

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000900831 – 3156-phosphogluconolactonase-like protein 2Add BLAST315

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei42PhosphoserineCombined sources1
Modified residuei64PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

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MaxQBi
P37262

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
P37262

PRoteomics IDEntifications database

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PRIDEi
P37262

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P37262

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

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BioGRIDi
31049, 82 interactors

Database of interacting proteins

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DIPi
DIP-8183N

Protein interaction database and analysis system

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IntActi
P37262, 6 interactors

Molecular INTeraction database

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MINTi
P37262

STRING: functional protein association networks

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STRINGi
4932.YCR073W-A

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

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RNActi
P37262, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG3147, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00550000075110

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

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HOGENOMi
CLU_053947_0_1_1

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
P37262

Identification of Orthologs from Complete Genome Data

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OMAi
IAMSQST

Family and domain databases

Conserved Domains Database

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CDDi
cd01400, 6PGL, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005900, 6-phosphogluconolactonase_DevB
IPR006148, Glc/Gal-6P_isomerase
IPR037171, NagB/RpiA_transferase-like
IPR039104, PGLS

The PANTHER Classification System

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PANTHERi
PTHR11054, PTHR11054, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF01182, Glucosamine_iso, 1 hit

Superfamily database of structural and functional annotation

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SUPFAMi
SSF100950, SSF100950, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01198, pgl, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P37262-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTTTVPKIFA FHEFSDVAEA VADHVVHAQD GALAPKNERK HSVPNISMNA
60 70 80 90 100
LDMTREASCK STASAAEGKS GSSGSGSGSS KPKKEKRFKI ALSGGSLIEV
110 120 130 140 150
LHEGLLKRDD VRWGDWDIYF ADERLVPFSS NESNYGCAKR KILDLIDTAK
160 170 180 190 200
YGTPKVYHID ESLIDDPQEC ADNYEKVLIR GFAGRDSVKL PMFDLFLLGC
210 220 230 240 250
APDGHIASLF PNFQDNLREK LAWVVPVENA PSGPSTRISL TIPVICHSHR
260 270 280 290 300
VTFVVEGATK APIIKTIMER PEKGLPSSIV NEGAAGRVSW FVDDDALTDV
310
LVTKKKYKFH QGLSI
Length:315
Mass (Da):34,501
Last modified:October 1, 1996 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7F0AAD76574AB276
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U46559 Genomic DNA Translation: AAB49322.1
X59720 Genomic DNA Translation: CAA42272.2
BK006937 Genomic DNA Translation: DAA07545.1

Protein sequence database of the Protein Information Resource

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PIRi
S53589

NCBI Reference Sequences

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RefSeqi
NP_009999.2, NM_001178815.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
YCR073W-A_mRNA; YCR073W-A; YCR073W-A

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
850437

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
sce:YCR073W-A

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U46559 Genomic DNA Translation: AAB49322.1
X59720 Genomic DNA Translation: CAA42272.2
BK006937 Genomic DNA Translation: DAA07545.1
PIRiS53589
RefSeqiNP_009999.2, NM_001178815.1

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi31049, 82 interactors
DIPiDIP-8183N
IntActiP37262, 6 interactors
MINTiP37262
STRINGi4932.YCR073W-A

PTM databases

iPTMnetiP37262

Proteomic databases

MaxQBiP37262
PaxDbiP37262
PRIDEiP37262

Genome annotation databases

EnsemblFungiiYCR073W-A_mRNA; YCR073W-A; YCR073W-A
GeneIDi850437
KEGGisce:YCR073W-A

Organism-specific databases

SGDiS000000718, SOL2
VEuPathDBiFungiDB:YCR073W-A

Phylogenomic databases

eggNOGiKOG3147, Eukaryota
GeneTreeiENSGT00550000075110
HOGENOMiCLU_053947_0_1_1
InParanoidiP37262
OMAiIAMSQST

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P37262
RNActiP37262, protein

Family and domain databases

CDDicd01400, 6PGL, 1 hit
InterProiView protein in InterPro
IPR005900, 6-phosphogluconolactonase_DevB
IPR006148, Glc/Gal-6P_isomerase
IPR037171, NagB/RpiA_transferase-like
IPR039104, PGLS
PANTHERiPTHR11054, PTHR11054, 1 hit
PfamiView protein in Pfam
PF01182, Glucosamine_iso, 1 hit
SUPFAMiSSF100950, SSF100950, 1 hit
TIGRFAMsiTIGR01198, pgl, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSOL2_YEAST
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P37262
Secondary accession number(s): D6VR76
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1996
Last modified: February 10, 2021
This is version 174 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast chromosome III
    Yeast (Saccharomyces cerevisiae) chromosome III: entries and gene names
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