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UniProtKB - P37194 (SLP_ECOLI)
Protein
Outer membrane protein Slp
Gene
slp
Organism
Escherichia coli (strain K12)
Status
Functioni
The induction of Slp may help to stabilize the outer membrane during carbon starvation and stationary phase.
GO - Molecular functioni
- identical protein binding Source: IntAct
Enzyme and pathway databases
BioCyci | EcoCyc:EG11890-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Outer membrane protein Slp |
Gene namesi | Name:slp Ordered Locus Names:b3506, JW3474 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Other locations
- Cell outer membrane 1 Publication; Lipid-anchor PROSITE-ProRule annotation1 Publication
Other locations
- cell outer membrane Source: UniProtKB-SubCell
- outer membrane Source: EcoCyc
Keywords - Cellular componenti
Cell outer membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 18 | Add BLAST | 18 | |
ChainiPRO_0000018187 | 19 – 188 | Outer membrane protein SlpAdd BLAST | 170 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Lipidationi | 19 | N-palmitoyl cysteinePROSITE-ProRule annotation1 Publication | 1 | |
Lipidationi | 19 | S-diacylglycerol cysteinePROSITE-ProRule annotation1 Publication | 1 |
Keywords - PTMi
Lipoprotein, PalmitateProteomic databases
jPOSTi | P37194 |
PaxDbi | P37194 |
PRIDEi | P37194 |
Expressioni
Inductioni
Induced upon starvation and slowed growth. cAMP/CRP-independent.
Interactioni
Subunit structurei
Forms homooligomers.
1 PublicationBinary interactionsi
P37194
With | #Exp. | IntAct |
---|---|---|
itself | 2 | EBI-907245,EBI-907245 |
GO - Molecular functioni
- identical protein binding Source: IntAct
Protein-protein interaction databases
BioGRIDi | 4261141, 148 interactors 852330, 1 interactor |
IntActi | P37194, 4 interactors |
STRINGi | 511145.b3506 |
Structurei
Family & Domainsi
Keywords - Domaini
SignalPhylogenomic databases
eggNOGi | COG3065, Bacteria |
HOGENOMi | CLU_100924_0_0_6 |
InParanoidi | P37194 |
PhylomeDBi | P37194 |
Family and domain databases
InterProi | View protein in InterPro IPR004658, OMP_Slp |
PANTHERi | PTHR37530, PTHR37530, 1 hit |
Pfami | View protein in Pfam PF03843, Slp, 1 hit |
PIRSFi | PIRSF004982, SlP, 1 hit |
TIGRFAMsi | TIGR00752, slp, 1 hit |
PROSITEi | View protein in PROSITE PS51257, PROKAR_LIPOPROTEIN, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P37194-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNMTKGALIL SLSFLLAACS SIPQNIKGNN QPDIQKSFVA VHNQPGLYVG
60 70 80 90 100
QQARFGGKVI NVINGKTDTL LEISVLPLDS YAKPDIEANY QGRLLARQSG
110 120 130 140 150
FLDPVNYRNH FVTILGTIQG EQPGFINKVP YNFLEVNMQG IQVWHLREVV
160 170 180
NTTYNLWDYG YGAFWPEPGW GAPYYTNAVS QVTPELVK
Sequence cautioni
The sequence AAB18482 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L23635 Genomic DNA Translation: AAA60370.1 U00039 Genomic DNA Translation: AAB18482.1 Different initiation. U00096 Genomic DNA Translation: AAC76531.2 AP009048 Genomic DNA Translation: BAE77788.1 |
PIRi | S47726 |
RefSeqi | NP_417963.4, NC_000913.3 WP_001350553.1, NZ_LN832404.1 |
Genome annotation databases
EnsemblBacteriai | AAC76531; AAC76531; b3506 BAE77788; BAE77788; BAE77788 |
GeneIDi | 948022 |
KEGGi | ecj:JW3474 eco:b3506 |
PATRICi | fig|511145.12.peg.3613 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L23635 Genomic DNA Translation: AAA60370.1 U00039 Genomic DNA Translation: AAB18482.1 Different initiation. U00096 Genomic DNA Translation: AAC76531.2 AP009048 Genomic DNA Translation: BAE77788.1 |
PIRi | S47726 |
RefSeqi | NP_417963.4, NC_000913.3 WP_001350553.1, NZ_LN832404.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 4261141, 148 interactors 852330, 1 interactor |
IntActi | P37194, 4 interactors |
STRINGi | 511145.b3506 |
Proteomic databases
jPOSTi | P37194 |
PaxDbi | P37194 |
PRIDEi | P37194 |
Genome annotation databases
EnsemblBacteriai | AAC76531; AAC76531; b3506 BAE77788; BAE77788; BAE77788 |
GeneIDi | 948022 |
KEGGi | ecj:JW3474 eco:b3506 |
PATRICi | fig|511145.12.peg.3613 |
Organism-specific databases
EchoBASEi | EB1836 |
Phylogenomic databases
eggNOGi | COG3065, Bacteria |
HOGENOMi | CLU_100924_0_0_6 |
InParanoidi | P37194 |
PhylomeDBi | P37194 |
Enzyme and pathway databases
BioCyci | EcoCyc:EG11890-MONOMER |
Miscellaneous databases
PROi | PR:P37194 |
Family and domain databases
InterProi | View protein in InterPro IPR004658, OMP_Slp |
PANTHERi | PTHR37530, PTHR37530, 1 hit |
Pfami | View protein in Pfam PF03843, Slp, 1 hit |
PIRSFi | PIRSF004982, SlP, 1 hit |
TIGRFAMsi | TIGR00752, slp, 1 hit |
PROSITEi | View protein in PROSITE PS51257, PROKAR_LIPOPROTEIN, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | SLP_ECOLI | |
Accessioni | P37194Primary (citable) accession number: P37194 Secondary accession number(s): P76709, Q2M7G8 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1994 |
Last sequence update: | October 1, 1994 | |
Last modified: | December 2, 2020 | |
This is version 141 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |