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Protein

Orphan antitoxin YagB

Gene

yagB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Putative antitoxin component of a type IV toxin-antitoxin (TA) system; its cognate toxin is unknown.Curated

Miscellaneous

Encoded by the CP4-6 prophage. An insertion element (ISX') seems to have deleted the end of yagB, fusing it to 13 insX' codons to make a 116 fusion pseudogene that may be expressed. The cognate toxin appears to have been deleted at the same time.Curated

GO - Biological processi

Keywordsi

Biological processToxin-antitoxin system

Enzyme and pathway databases

BioCyciEcoCyc:EG12339-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Orphan antitoxin YagB
Gene namesi
Name:yagB
Ordered Locus Names:b0266, JW0259
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12339 yagB

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001685551 – 116Orphan antitoxin YagBAdd BLAST116

Proteomic databases

PRIDEiP37008

Interactioni

Protein-protein interaction databases

BioGridi4262794, 8 interactors
IntActiP37008, 4 interactors
STRINGi316385.ECDH10B_0253

Structurei

3D structure databases

ProteinModelPortaliP37008
SMRiP37008
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CbeA/YafW/YfjZ antitoxin family.Curated

Phylogenomic databases

HOGENOMiHOG000290944
KOiK18838
PhylomeDBiP37008

Family and domain databases

InterProiView protein in InterPro
IPR009320 Antitoxin_CbeA
IPR038025 CbeA_sf
PfamiView protein in Pfam
PF06154 CbeA_antitoxin, 1 hit
SUPFAMiSSF143737 SSF143737, 1 hit

Sequencei

Sequence statusi: Complete.

P37008-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNKDSTQTWG LKRDITPCFG ARLVQEGHRL HFLADRAGFT GSFSEVQTLQ
60 70 80 90 100
LDEAFPHFVA HLELMLLSCE LNPRYAHCVT LYRNGLTGEA DTLGSHGYVY
110
IAILNRHGFN RHLRVI
Length:116
Mass (Da):13,184
Last modified:October 1, 1996 - v2
Checksum:iA87EC473D837685E
GO

Sequence cautioni

The sequence AAB08687 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence L20943 differs from that shown. Reason: Frameshift at position 33.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L20943 Unassigned DNA No translation available.
U70214 Genomic DNA Translation: AAB08687.1 Different initiation.
U00096 Genomic DNA No translation available.
AP009048 Genomic DNA Translation: BAE76052.1
PIRiB64752
RefSeqiWP_001030800.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiBAE76052; BAE76052; BAE76052
KEGGiecj:JW0259
PATRICifig|83333.103.peg.1021

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L20943 Unassigned DNA No translation available.
U70214 Genomic DNA Translation: AAB08687.1 Different initiation.
U00096 Genomic DNA No translation available.
AP009048 Genomic DNA Translation: BAE76052.1
PIRiB64752
RefSeqiWP_001030800.1, NZ_LN832404.1

3D structure databases

ProteinModelPortaliP37008
SMRiP37008
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262794, 8 interactors
IntActiP37008, 4 interactors
STRINGi316385.ECDH10B_0253

Proteomic databases

PRIDEiP37008

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAE76052; BAE76052; BAE76052
KEGGiecj:JW0259
PATRICifig|83333.103.peg.1021

Organism-specific databases

EchoBASEiEB2243
EcoGeneiEG12339 yagB

Phylogenomic databases

HOGENOMiHOG000290944
KOiK18838
PhylomeDBiP37008

Enzyme and pathway databases

BioCyciEcoCyc:EG12339-MONOMER

Family and domain databases

InterProiView protein in InterPro
IPR009320 Antitoxin_CbeA
IPR038025 CbeA_sf
PfamiView protein in Pfam
PF06154 CbeA_antitoxin, 1 hit
SUPFAMiSSF143737 SSF143737, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiYAGB_ECOLI
AccessioniPrimary (citable) accession number: P37008
Secondary accession number(s): P77583, Q2MCF4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: October 1, 1996
Last modified: November 7, 2018
This is version 123 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
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Main funding by: National Institutes of Health

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