Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Potassium-transporting ATPase KdpF subunit

Gene

kdpF

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm (PubMed:23930894). This subunit may be involved in stabilization of the complex (PubMed:10608856).2 Publications

GO - Molecular functioni

  • potassium-transporting ATPase activity Source: EcoCyc

GO - Biological processi

  • ATP hydrolysis coupled cation transmembrane transport Source: EcoCyc
  • potassium ion transmembrane transport Source: EcoCyc
  • regulation of ATPase activity Source: InterPro

Keywordsi

Biological processIon transport, Potassium transport, Transport
LigandPotassium

Enzyme and pathway databases

BioCyciEcoCyc:MONOMER0-12
MetaCyc:MONOMER0-12

Protein family/group databases

TCDBi3.A.3.7.1 the p-type atpase (p-atpase) superfamily

Names & Taxonomyi

Protein namesi
Recommended name:
Potassium-transporting ATPase KdpF subunitCurated
Alternative name(s):
ATP phosphohydrolase [potassium-transporting] F chainCurated
Potassium-binding and translocating subunit FCurated
Potassium-translocating ATPase F chainCurated
Gene namesi
Name:kdpF
Ordered Locus Names:b4513, JW0687
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12126 kdpF

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei4 – 24HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • integral component of plasma membrane Source: EcoCyc
  • potassium ion-transporting ATPase complex Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

Pathology & Biotechi

Disruption phenotypei

Inactivation of kdpF still leads to a functional KdpABC complex in vivo. Deletion impairs ATPase activity of the complex in vitro.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000842991 – 29Potassium-transporting ATPase KdpF subunitAdd BLAST29

Proteomic databases

PaxDbiP36937

Expressioni

Inductioni

Transcriptionally regulated by the KdpD/KdpE two-component regulatory system.1 Publication

Interactioni

Subunit structurei

The system is composed of three essential subunits: KdpA, KdpB and KdpC (PubMed:10608856). The complex also contains KdpF, a small non-essential subunit (PubMed:10608856). The KdpFABC complex exists as a dimer above concentrations of 30-50 nM, whereas the complex exists as a functional monomer at lower concentrations (PubMed:18298081).2 Publications

Protein-protein interaction databases

BioGridi4259926, 3 interactors
STRINGi316385.ECDH10B_0765

Structurei

Secondary structure

129
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi3 – 24Combined sources22

3D structure databases

SMRiP36937
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the KdpF family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

KOiK01545

Family and domain databases

InterProiView protein in InterPro
IPR011726 KdpF
PfamiView protein in Pfam
PF09604 Potass_KdpF, 1 hit
TIGRFAMsiTIGR02115 potass_kdpF, 1 hit

Sequencei

Sequence statusi: Complete.

P36937-1 [UniParc]FASTAAdd to basket

« Hide

        10         20 
MSAGVITGVL LVFLLLGYLV YALINAEAF
Length:29
Mass (Da):3,072
Last modified:June 1, 1994 - v1
Checksum:iA925E36F96B17820
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
K02670 Genomic DNA No translation available.
U00096 Genomic DNA Translation: ABD18643.1
AP009048 Genomic DNA Translation: BAA35357.1
PIRiT48910
RefSeqiWP_001272653.1, NZ_LN832404.1
YP_588443.1, NC_000913.3

Genome annotation databases

EnsemblBacteriaiABD18643; ABD18643; b4513
BAA35357; BAA35357; BAA35357
GeneIDi948946
KEGGiecj:JW0687
eco:b4513
PATRICifig|511145.12.peg.729

Similar proteinsi

Entry informationi

Entry nameiKDPF_ECOLI
AccessioniPrimary (citable) accession number: P36937
Secondary accession number(s): Q2EEQ9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: July 18, 2018
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health