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Protein

Putative hydrolase EbsB

Gene

ebsB

Organism
Enterococcus faecalis (strain ATCC 700802 / V583)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Seems to play some role in the cell surface expression of a chromosomally encoded receptor, named enterococcal binding substance (EBS), that mediates mating aggregate formation. Might interfere with the synthesis or assembly of EBS and function as a cell wall hydrolase.1 Publication

Cofactori

Mg2+By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi7Magnesium 1By similarity1
Metal bindingi7Magnesium 2By similarity1
Metal bindingi45Magnesium 1By similarity1
Metal bindingi71Magnesium 1By similarity1
Metal bindingi120Magnesium 2By similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase
LigandMagnesium, Metal-binding

Enzyme and pathway databases

BioCyciEFAE226185:G1G0C-1706-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Putative hydrolase EbsBCurated (EC:3.-.-.-Curated)
Gene namesi
Name:ebsB1 Publication
Ordered Locus Names:EF_1728
OrganismiEnterococcus faecalis (strain ATCC 700802 / V583)
Taxonomic identifieri226185 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesEnterococcaceaeEnterococcus
Proteomesi
  • UP000001415 Componenti: Chromosome

Subcellular locationi

  • cell wall 1 Publication
  • Note: Cell wall location was proposed in PubMed:8226689 based on a low sequence similarity to a cell wall hydrolase and a penicillin-binding protein. However, this protein has a best similarity to ribonucleases H which are expected to be cytoplasmic.Curated

GO - Cellular componenti

Keywords - Cellular componenti

Cell wall, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001954321 – 135Putative hydrolase EbsBAdd BLAST135

Interactioni

Protein-protein interaction databases

STRINGi226185.EF1728

Structurei

3D structure databases

ProteinModelPortaliP36921
SMRiP36921
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 128RNase HPROSITE-ProRule annotationAdd BLAST128

Sequence similaritiesi

Belongs to the RNase H family. EbsB subfamily.Curated

Phylogenomic databases

eggNOGiENOG4105VND Bacteria
COG0328 LUCA
KOiK03469
OMAiNTDHERW

Family and domain databases

Gene3Di3.30.420.10, 1 hit
InterProiView protein in InterPro
IPR012337 RNaseH-like_sf
IPR002156 RNaseH_domain
IPR036397 RNaseH_sf
SUPFAMiSSF53098 SSF53098, 1 hit
PROSITEiView protein in PROSITE
PS50879 RNASE_H, 1 hit

Sequencei

Sequence statusi: Complete.

P36921-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLRIYVDAAT KGNPGESGGG IVYLTDQSRQ QLHVPLGIVS NHEAEFKVLI
60 70 80 90 100
EALKKAIANE DNQQTVLLHS DSKIVVQTIE KNYAKNEKYQ PYLAEYQQLE
110 120 130
KNFPLLLIEW LPESQNKAAD MLARQALQKF YPNKK
Length:135
Mass (Da):15,371
Last modified:April 23, 2003 - v2
Checksum:iB03A7F80518862CD
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti55K → Q in AAC36852 (PubMed:8226689).Curated1
Sequence conflicti109E → K in AAC36852 (PubMed:8226689).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L23802 Unassigned DNA Translation: AAC36852.1
AE016830 Genomic DNA Translation: AAO81503.1
PIRiB49939
RefSeqiNP_815433.1, NC_004668.1
WP_002369306.1, NZ_KE136528.1

Genome annotation databases

EnsemblBacteriaiAAO81503; AAO81503; EF_1728
GeneIDi1200620
KEGGiefa:EF1728
PATRICifig|226185.45.peg.1784

Similar proteinsi

Entry informationi

Entry nameiEBSB_ENTFA
AccessioniPrimary (citable) accession number: P36921
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: April 23, 2003
Last modified: February 28, 2018
This is version 102 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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