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Entry version 197 (16 Oct 2019)
Sequence version 1 (01 Jun 1994)
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Protein

ATP synthase subunit gamma, mitochondrial

Gene

ATP5F1C

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F1 domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha3beta3. Rotation of the central stalk against the surrounding alpha3beta3 subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processATP synthesis, Hydrogen ion transport, Ion transport, Transport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-163210 Formation of ATP by chemiosmotic coupling
R-HSA-8949613 Cristae formation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
ATP synthase subunit gamma, mitochondrialCurated
Alternative name(s):
ATP synthase F1 subunit gammaImported
F-ATPase gamma subunit
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ATP5F1CImported
Synonyms:ATP5CImported, ATP5C1Imported, ATP5CL1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:833 ATP5F1C

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
108729 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P36542

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

CF(1), Membrane, Mitochondrion, Mitochondrion inner membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
509

Open Targets

More...
OpenTargetsi
ENSG00000165629

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA25125

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
P36542

Chemistry databases

Drug and drug target database

More...
DrugBanki
DB07384 1-ACETYL-2-CARBOXYPIPERIDINE
DB07394 AUROVERTIN B
DB08629 N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE
DB08399 PICEATANNOL
DB04216 Quercetin

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ATP5C1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
543875

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 25MitochondrionAdd BLAST25
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000000268526 – 298ATP synthase subunit gamma, mitochondrialAdd BLAST273

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei39N6-acetyllysineBy similarity1
Modified residuei49N6-succinyllysineBy similarity1
Modified residuei55N6-acetyllysineCombined sources1
Modified residuei115N6-acetyllysine; alternateBy similarity1
Modified residuei115N6-succinyllysine; alternateBy similarity1
Modified residuei146PhosphoserineCombined sources1
Modified residuei154N6-acetyllysine; alternateCombined sources1
Modified residuei154N6-succinyllysine; alternateBy similarity1
Modified residuei197N6-acetyllysineCombined sources1
Modified residuei270N6-succinyllysineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P36542

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P36542

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
P36542

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P36542

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P36542

PeptideAtlas

More...
PeptideAtlasi
P36542

PRoteomics IDEntifications database

More...
PRIDEi
P36542

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
55207 [P36542-1]
55208 [P36542-2]

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
P36542-1 [P36542-1]
P36542-2 [P36542-2]

2D gel databases

University College Dublin 2-DE Proteome Database

More...
UCD-2DPAGEi
P36542

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P36542

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P36542

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
P36542

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Isoform Heart is expressed specifically in the heart and skeletal muscle, which require rapid energy supply. Isoform Liver is expressed in the brain, liver and kidney. Isoform Heart and Isoform Liver are expressed in the skin, intestine, stomach and aorta.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000165629 Expressed in 233 organ(s), highest expression level in myocardium

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P36542 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA060949

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a, b and c.

Component of an ATP synthase complex composed of ATP5PB, ATP5MC1, ATP5F1E, ATP5PD, ATP5ME, ATP5PF, ATP5MF, MT-ATP6, MT-ATP8, ATP5F1A, ATP5F1B, ATP5F1D, ATP5F1C, ATP5PO, ATP5MG, ATP5MD and ATP5MPL (By similarity).

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
106997, 173 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
P36542

Protein interaction database and analysis system

More...
IntActi
P36542, 105 interactors

Molecular INTeraction database

More...
MINTi
P36542

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000349142

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
P36542

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ATPase gamma chain family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1531 Eukaryota
COG0224 LUCA

Ensembl GeneTree

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GeneTreei
ENSGT00390000006837

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

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HOGENOMi
HOG000215911

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P36542

KEGG Orthology (KO)

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KOi
K02136

Identification of Orthologs from Complete Genome Data

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OMAi
MQITSAM

Database of Orthologous Groups

More...
OrthoDBi
841252at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P36542

TreeFam database of animal gene trees

More...
TreeFami
TF105765

Family and domain databases

Conserved Domains Database

More...
CDDi
cd12151 F1-ATPase_gamma, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR035968 ATP_synth_F1_ATPase_gsu
IPR000131 ATP_synth_F1_gsu
IPR023632 ATP_synth_F1_gsu_CS

The PANTHER Classification System

More...
PANTHERi
PTHR11693 PTHR11693, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF00231 ATP-synt, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00126 ATPASEGAMMA

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52943 SSF52943, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01146 ATPsyn_F1gamma, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00153 ATPASE_GAMMA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform Liver (identifier: P36542-1) [UniParc]FASTAAdd to basket
Also known as: L

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MFSRAGVAGL SAWTLQPQWI QVRNMATLKD ITRRLKSIKN IQKITKSMKM
60 70 80 90 100
VAAAKYARAE RELKPARIYG LGSLALYEKA DIKGPEDKKK HLLIGVSSDR
110 120 130 140 150
GLCGAIHSSI AKQMKSEVAT LTAAGKEVML VGIGDKIRGI LYRTHSDQFL
160 170 180 190 200
VAFKEVGRKP PTFGDASVIA LELLNSGYEF DEGSIIFNKF RSVISYKTEE
210 220 230 240 250
KPIFSLNTVA SADSMSIYDD IDADVLQNYQ EYNLANIIYY SLKESTTSEQ
260 270 280 290
SARMTAMDNA SKNASEMIDK LTLTFNRTRQ AVITKELIEI ISGAAALD
Length:298
Mass (Da):32,996
Last modified:June 1, 1994 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i021A95168FD53E04
GO
Isoform Heart (identifier: P36542-2) [UniParc]FASTAAdd to basket
Also known as: H

The sequence of this isoform differs from the canonical sequence as follows:
     298-298: Missing.

Show »
Length:297
Mass (Da):32,881
Checksum:iCA95168FD53E0447
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti45T → A in AAH16812 (PubMed:15489334).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_000439298Missing in isoform Heart. 2 Publications1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
D16561 Genomic DNA Translation: BAA03994.1
D16561 Genomic DNA Translation: BAA03995.1
D16562 mRNA Translation: BAA03996.1
D16563 mRNA Translation: BAA03997.1
AK292896 mRNA Translation: BAF85585.1
CR457403 mRNA Translation: CAG33684.1
AL353754 Genomic DNA No translation available.
AL158044 Genomic DNA No translation available.
CH471072 Genomic DNA Translation: EAW86372.1
CH471072 Genomic DNA Translation: EAW86373.1
BC000470 mRNA Translation: AAH00470.1
BC000931 mRNA Translation: AAH00931.1
BC013394 mRNA Translation: AAH13394.1
BC016812 mRNA Translation: AAH16812.1
BC020824 mRNA Translation: AAH20824.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS31142.1 [P36542-1]
CCDS7081.1 [P36542-2]

Protein sequence database of the Protein Information Resource

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PIRi
A49108

NCBI Reference Sequences

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RefSeqi
NP_001001973.1, NM_001001973.2 [P36542-1]
NP_005165.1, NM_005174.3 [P36542-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000335698; ENSP00000338568; ENSG00000165629 [P36542-2]
ENST00000356708; ENSP00000349142; ENSG00000165629 [P36542-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
509

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:509

UCSC genome browser

More...
UCSCi
uc001iju.4 human [P36542-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D16561 Genomic DNA Translation: BAA03994.1
D16561 Genomic DNA Translation: BAA03995.1
D16562 mRNA Translation: BAA03996.1
D16563 mRNA Translation: BAA03997.1
AK292896 mRNA Translation: BAF85585.1
CR457403 mRNA Translation: CAG33684.1
AL353754 Genomic DNA No translation available.
AL158044 Genomic DNA No translation available.
CH471072 Genomic DNA Translation: EAW86372.1
CH471072 Genomic DNA Translation: EAW86373.1
BC000470 mRNA Translation: AAH00470.1
BC000931 mRNA Translation: AAH00931.1
BC013394 mRNA Translation: AAH13394.1
BC016812 mRNA Translation: AAH16812.1
BC020824 mRNA Translation: AAH20824.1
CCDSiCCDS31142.1 [P36542-1]
CCDS7081.1 [P36542-2]
PIRiA49108
RefSeqiNP_001001973.1, NM_001001973.2 [P36542-1]
NP_005165.1, NM_005174.3 [P36542-2]

3D structure databases

SMRiP36542
ModBaseiSearch...

Protein-protein interaction databases

BioGridi106997, 173 interactors
CORUMiP36542
IntActiP36542, 105 interactors
MINTiP36542
STRINGi9606.ENSP00000349142

Chemistry databases

DrugBankiDB07384 1-ACETYL-2-CARBOXYPIPERIDINE
DB07394 AUROVERTIN B
DB08629 N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE
DB08399 PICEATANNOL
DB04216 Quercetin

PTM databases

iPTMnetiP36542
PhosphoSitePlusiP36542
SwissPalmiP36542

Polymorphism and mutation databases

BioMutaiATP5C1
DMDMi543875

2D gel databases

UCD-2DPAGEiP36542

Proteomic databases

EPDiP36542
jPOSTiP36542
MassIVEiP36542
MaxQBiP36542
PaxDbiP36542
PeptideAtlasiP36542
PRIDEiP36542
ProteomicsDBi55207 [P36542-1]
55208 [P36542-2]
TopDownProteomicsiP36542-1 [P36542-1]
P36542-2 [P36542-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
509

Genome annotation databases

EnsembliENST00000335698; ENSP00000338568; ENSG00000165629 [P36542-2]
ENST00000356708; ENSP00000349142; ENSG00000165629 [P36542-1]
GeneIDi509
KEGGihsa:509
UCSCiuc001iju.4 human [P36542-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
509
DisGeNETi509

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ATP5F1C
HGNCiHGNC:833 ATP5F1C
HPAiHPA060949
MIMi108729 gene
neXtProtiNX_P36542
OpenTargetsiENSG00000165629
PharmGKBiPA25125

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG1531 Eukaryota
COG0224 LUCA
GeneTreeiENSGT00390000006837
HOGENOMiHOG000215911
InParanoidiP36542
KOiK02136
OMAiMQITSAM
OrthoDBi841252at2759
PhylomeDBiP36542
TreeFamiTF105765

Enzyme and pathway databases

ReactomeiR-HSA-163210 Formation of ATP by chemiosmotic coupling
R-HSA-8949613 Cristae formation

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
ATP5C1 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
ATP5C1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
509
PharosiP36542

Protein Ontology

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PROi
PR:P36542

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000165629 Expressed in 233 organ(s), highest expression level in myocardium
GenevisibleiP36542 HS

Family and domain databases

CDDicd12151 F1-ATPase_gamma, 1 hit
InterProiView protein in InterPro
IPR035968 ATP_synth_F1_ATPase_gsu
IPR000131 ATP_synth_F1_gsu
IPR023632 ATP_synth_F1_gsu_CS
PANTHERiPTHR11693 PTHR11693, 1 hit
PfamiView protein in Pfam
PF00231 ATP-synt, 1 hit
PRINTSiPR00126 ATPASEGAMMA
SUPFAMiSSF52943 SSF52943, 1 hit
TIGRFAMsiTIGR01146 ATPsyn_F1gamma, 1 hit
PROSITEiView protein in PROSITE
PS00153 ATPASE_GAMMA, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiATPG_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P36542
Secondary accession number(s): A8KA31
, Q5VYP3, Q6I9V2, Q96AS8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: October 16, 2019
This is version 197 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
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