UniProtKB - P36508 (ZNF76_HUMAN)

BLAST

>sp|P36508|ZNF76_HUMAN Zinc finger protein 76 OS=Homo sapiens OX=9606 GN=ZNF76 PE=1 SV=2
MESLGLHTVTLSDGTTAYVQQAVKGEKLLEGQVIQLEDGTTAYIHQVTVQKEALSFEDGQ
PVQLEDGSMAYIHRTPREGYDPSTLEAVQLEDGSTAYIHHPVAVPSESTILAVQTEVGLE
DLAAEDDEGFSADAVVALEQYASKVLHDSQIPRNGKGQQVGDRAFRCGYKGCGRLYTTAH
HLKVHERAHTGDRPYRCDFPSCGKAFATGYGLKSHVRTHTGEKPYKCPEELCSKAFKTSG
DLQKHVRTHTGERPFQCPFEGCGRSFTTSNIRKVHVRTHTGERPYTCPEPHCGRGFTSAT
NYKNHVRIHTGEKPYVCTVPGCGKRFTEYSSLYKHHVVHTHCKPYTCSTCGKTYRQTSTL
AMHKRSAHGELEATEESEQALYEQQQLEAASAAEESPPPKRPRIAYLSEVKEERDDIPAQ
VAMVTEEDGAPQVALITQDGAQQVSLSPEDLQALGSAISMVTQHGSTTLTIPSPDADLAT
SGTHTVTMVSADGTQTQPVTIITSGAVVAEDSSVASLRHQQVALLATANGTHIAVQLEEQ
QTLEEAINVATAAMQQGAVTLETTVSESGC

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History
Entry version 175 (07 Nov 2018)
Sequence version 2 (02 May 2002)
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Protein

Zinc finger protein 76

Gene

ZNF76

Organism

Homo sapiens (Human)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

May be involved in transcriptional regulation.

Regions

Feature key	Position(s)	DescriptionActions	Length
Zinc fingerⁱ	165 – 189	C2H2-type 1PROSITE-ProRule annotationAdd BLAST	25
Zinc fingerⁱ	195 – 219	C2H2-type 2PROSITE-ProRule annotationAdd BLAST	25
Zinc fingerⁱ	225 – 249	C2H2-type 3PROSITE-ProRule annotationAdd BLAST	25
Zinc fingerⁱ	255 – 279	C2H2-type 4PROSITE-ProRule annotationAdd BLAST	25
Zinc fingerⁱ	285 – 309	C2H2-type 5PROSITE-ProRule annotationAdd BLAST	25
Zinc fingerⁱ	315 – 339	C2H2-type 6PROSITE-ProRule annotationAdd BLAST	25
Zinc fingerⁱ	345 – 368	C2H2-type 7PROSITE-ProRule annotationAdd BLAST	24

GO - Molecular functionⁱ

DNA-binding transcription activator activity, RNA polymerase II-specific
Source: NTNU_SB
Inferred from direct assayⁱ
- 10893243
DNA-binding transcription factor activity, RNA polymerase II-specific Source: NTNU_SB
metal ion binding Source: UniProtKB-KW
sequence-specific DNA binding
Source: NTNU_SB
Inferred from direct assayⁱ
- 10893243

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

positive regulation of transcription by RNA polymerase II
Source: NTNU_SB
Inferred from direct assayⁱ
- 10893243
regulation of transcription by RNA polymerase II
Source: ProtInc
Traceable author statementⁱ
- 9705341
regulation of transcription by RNA polymerase III
Source: ProtInc
Traceable author statementⁱ
- 9705341

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	DNA-binding
Biological process	Transcription, Transcription regulation
Ligand	Metal-binding, Zinc

Enzyme and pathway databases

SIGNORⁱ	P36508

SIGNORⁱ

P36508

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Zinc finger protein 76 Alternative name(s): Zinc finger protein 523
Gene namesⁱ	Name:ZNF76 Synonyms:D6S229E, ZNF523
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 6

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000065029.14
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:13149 ZNF76
MIMⁱ	194549 gene
neXtProtⁱ	NX_P36508

Keywords - Cellular componentⁱ

Nucleus

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000065029
PharmGKBⁱ	PA37723

Polymorphism and mutation databases

BioMutaⁱ	ZNF76
DMDMⁱ	20455531

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000047386	1 – 570	Zinc finger protein 76Add BLAST		570

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Cross-linkⁱ	24	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources

Keywords - PTMⁱ

Isopeptide bond, Ubl conjugation

Proteomic databases

EPDⁱ	P36508
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	P36508
PaxDbⁱ	P36508
PeptideAtlas More...PeptideAtlasⁱ	P36508
PRIDEⁱ	P36508
ProteomicsDBⁱ	55204 55205 [P36508-2]

PTM databases

iPTMnetⁱ	P36508
PhosphoSitePlusⁱ	P36508

Expressionⁱ

Tissue specificityⁱ

Testis.

Gene expression databases

Bgeeⁱ	ENSG00000065029 Expressed in 206 organ(s), highest expression level in left lobe of thyroid gland
CleanExⁱ	HS_ZNF76
ExpressionAtlasⁱ	P36508 baseline and differential
Genevisibleⁱ	P36508 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA030090 HPA030091

HPAⁱ

HPA030090
HPA030091

Interactionⁱ

Binary interactionsⁱ

With	Entry	#Exp.	IntAct
ENKD1	Q9H0I2	4	EBI-7254550,EBI-744099
NEDD9	Q14511-2	4	EBI-7254550,EBI-11746523
POGZ	Q7Z3K3	4	EBI-7254550,EBI-1389308

Protein-protein interaction databases

BioGridⁱ	113448, 14 interactors
IntActⁱ	P36508, 85 interactors
Molecular INTeraction database More...MINTⁱ	P36508
STRINGⁱ	9606.ENSP00000363064

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P36508
SMRⁱ	P36508
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Repeatⁱ	34 – 45	1Add BLAST	12
Repeatⁱ	62 – 73	2Add BLAST	12
Repeatⁱ	88 – 99	3Add BLAST	12

Region

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Regionⁱ	34 – 99	3 X 12 AA approximate repeatsAdd BLAST		66

Sequence similaritiesⁱ

Belongs to the krueppel C2H2-type zinc-finger protein family.Curated

Zinc finger

Feature key	Position(s)	DescriptionActions	Length
Zinc fingerⁱ	165 – 189	C2H2-type 1PROSITE-ProRule annotationAdd BLAST	25
Zinc fingerⁱ	195 – 219	C2H2-type 2PROSITE-ProRule annotationAdd BLAST	25
Zinc fingerⁱ	225 – 249	C2H2-type 3PROSITE-ProRule annotationAdd BLAST	25
Zinc fingerⁱ	255 – 279	C2H2-type 4PROSITE-ProRule annotationAdd BLAST	25
Zinc fingerⁱ	285 – 309	C2H2-type 5PROSITE-ProRule annotationAdd BLAST	25
Zinc fingerⁱ	315 – 339	C2H2-type 6PROSITE-ProRule annotationAdd BLAST	25
Zinc fingerⁱ	345 – 368	C2H2-type 7PROSITE-ProRule annotationAdd BLAST	24

Keywords - Domainⁱ

Repeat, Zinc-finger

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00910000144040
HOGENOMⁱ	HOG000118073
HOVERGENⁱ	HBG053078
InParanoidⁱ	P36508
KEGG Orthology (KO) More...KOⁱ	K20828
OMAⁱ	SMVTQHS
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0N38
PhylomeDBⁱ	P36508
TreeFamⁱ	TF333498

Family and domain databases

InterProⁱ	View protein in InterPro IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00096 zf-C2H2, 4 hits
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 7 hits
SUPFAMⁱ	SSF57667 SSF57667, 4 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 7 hits PS50157 ZINC_FINGER_C2H2_2, 7 hits

Sequences (2+)ⁱ

Sequence statusⁱ: Complete.

This entry describes 2 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show all Align All

Isoform 2 (identifier: P36508-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MESLGLHTVT LSDGTTAYVQ QAVKGEKLLE GQVIQLEDGT TAYIHQVTVQ 
        60         70         80         90        100
KEALSFEDGQ PVQLEDGSMA YIHRTPREGY DPSTLEAVQL EDGSTAYIHH 
       110        120        130        140        150
PVAVPSESTI LAVQTEVGLE DLAAEDDEGF SADAVVALEQ YASKVLHDSQ 
       160        170        180        190        200
IPRNGKGQQV GDRAFRCGYK GCGRLYTTAH HLKVHERAHT GDRPYRCDFP 
       210        220        230        240        250
SCGKAFATGY GLKSHVRTHT GEKPYKCPEE LCSKAFKTSG DLQKHVRTHT 
       260        270        280        290        300
GERPFQCPFE GCGRSFTTSN IRKVHVRTHT GERPYTCPEP HCGRGFTSAT 
       310        320        330        340        350
NYKNHVRIHT GEKPYVCTVP GCGKRFTEYS SLYKHHVVHT HCKPYTCSTC 
       360        370        380        390        400
GKTYRQTSTL AMHKRSAHGE LEATEESEQA LYEQQQLEAA SAAEESPPPK 
       410        420        430        440        450
RPRIAYLSEV KEERDDIPAQ VAMVTEEDGA PQVALITQDG AQQVSLSPED 
       460        470        480        490        500
LQALGSAISM VTQHGSTTLT IPSPDADLAT SGTHTVTMVS ADGTQTQPVT 
       510        520        530        540        550
IITSGAVVAE DSSVASLRHQ QVALLATANG THIAVQLEEQ QTLEEAINVA 
       560        570
TAAMQQGAVT LETTVSESGC

Length:570

Mass (Da):61,831

Last modified:May 2, 2002 - v2

Checksum:ⁱ333C99E0E79D86C2

Isoform 1 (identifier: P36508-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
444-498: Missing.

« Hide

        10         20         30         40         50
MESLGLHTVT LSDGTTAYVQ QAVKGEKLLE GQVIQLEDGT TAYIHQVTVQ 
        60         70         80         90        100
KEALSFEDGQ PVQLEDGSMA YIHRTPREGY DPSTLEAVQL EDGSTAYIHH 
       110        120        130        140        150
PVAVPSESTI LAVQTEVGLE DLAAEDDEGF SADAVVALEQ YASKVLHDSQ 
       160        170        180        190        200
IPRNGKGQQV GDRAFRCGYK GCGRLYTTAH HLKVHERAHT GDRPYRCDFP 
       210        220        230        240        250
SCGKAFATGY GLKSHVRTHT GEKPYKCPEE LCSKAFKTSG DLQKHVRTHT 
       260        270        280        290        300
GERPFQCPFE GCGRSFTTSN IRKVHVRTHT GERPYTCPEP HCGRGFTSAT 
       310        320        330        340        350
NYKNHVRIHT GEKPYVCTVP GCGKRFTEYS SLYKHHVVHT HCKPYTCSTC 
       360        370        380        390        400
GKTYRQTSTL AMHKRSAHGE LEATEESEQA LYEQQQLEAA SAAEESPPPK 
       410        420        430        440        450
RPRIAYLSEV KEERDDIPAQ VAMVTEEDGA PQVALITQDG AQQVTIITSG 
       460        470        480        490        500
AVVAEDSSVA SLRHQQVALL ATANGTHIAV QLEEQQTLEE AINVATAAMQ 
       510 
QGAVTLETTV SESGC

Note: No experimental confirmation available.

Show »

Length:515

Mass (Da):56,324

Checksum:ⁱ473D193AE00E7FB1

Computationally mapped potential isoform sequencesⁱ

There are 3 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

E7EX64	E7EX64_HUMAN	Zinc finger protein 76 Zinc finger protein 76	ZNF76	340	Annotation score:
F8W971	F8W971_HUMAN	Zinc finger protein 76 Zinc finger protein 76	ZNF76	151	Annotation score:
H7C513	H7C513_HUMAN	Zinc finger protein 76 Zinc finger protein 76	ZNF76	101	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	334 – 335	KH → ND in AAA98739 (PubMed:1427894).Curated		2

Natural variant

Feature key	Position(s)	DescriptionActions	Length
Natural variantⁱVAR_033546	48	T → M. Corresponds to variant dbSNP:rs2228265Ensembl.	1
Natural variantⁱVAR_033547	272	R → C. Corresponds to variant dbSNP:rs33959228Ensembl.	1
Natural variantⁱVAR_033548	403	R → Q. Corresponds to variant dbSNP:rs35582935Ensembl.	1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_006894	444 – 498	Missing in isoform 1. 1 PublicationAdd BLAST		55

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	M91592 mRNA Translation: AAA98739.1 BT007316 mRNA Translation: AAP35980.1 BC000133 mRNA Translation: AAH00133.1 BC002549 mRNA Translation: AAH02549.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS4801.1 [P36508-1] CCDS75435.1 [P36508-2]
PIRⁱ	A44256
NCBI Reference Sequences More...RefSeqⁱ	NP_001278961.1, NM_001292032.1 [P36508-2] NP_003418.2, NM_003427.4 [P36508-1] XP_016866738.1, XM_017011249.1 [P36508-1]
UniGeneⁱ	Hs.388024

Genome annotation databases

Ensemblⁱ	ENST00000339411; ENSP00000344097; ENSG00000065029 [P36508-2] ENST00000373953; ENSP00000363064; ENSG00000065029 [P36508-1]
GeneIDⁱ	7629
KEGGⁱ	hsa:7629
UCSC genome browser More...UCSCⁱ	uc003oki.2 human [P36508-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing, Polymorphism

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
P36508	Zinc finger protein 76 (Expressed in testis), isoform CRA_b		HUMAN		570	UniRef100_P36508
P36508-2	Zinc finger protein 76 (Expressed in testis), isoform CRA_c		HUMAN		515	UniRef100_A0A024RCW5

Protein	Similar proteins		Species	Score	Length	Source
P36508	Zinc finger protein 76 (Expressed in testis), isoform CRA_b		HUMAN		570	UniRef90_P36508
Zinc finger protein 76		CRIGR		676
Zinc finger protein 76		wild yak		582
zinc finger protein 76 isoform X1		TURTR		578
Uncharacterized protein		BOVIN		571
+88
P36508-2	Zinc finger protein 76 (Expressed in testis), isoform CRA_c		HUMAN		515	UniRef90_A0A024RCW5
zinc finger protein 76 isoform X3		BALAS		515
Uncharacterized protein		CALJA		515
zinc finger protein 76 isoform X2		ODORO		515
zinc finger protein 76 isoform X3		Enhydra lutris kenyoni		515
+20

Protein	Similar proteins		Species	Score	Length	Source
P36508	Zinc finger protein 76 (Expressed in testis), isoform CRA_b		HUMAN		570	UniRef50_P36508
Zinc finger protein 76		CRIGR		676
Zinc finger protein 76		wild yak		582
zinc finger protein 76 isoform X1		TURTR		578
Uncharacterized protein		BOVIN		571
+176
P36508-2	Zinc finger protein 76		SHEEP		536	UniRef50_W5PPR8
Uncharacterized protein		PROCO		515
Uncharacterized protein		AOTNA		515
zinc finger protein 76 isoform X4		TURTR		515
zinc finger protein 76 isoform X4		Yangtze finless porpoise		515
+60

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	M91592 mRNA Translation: AAA98739.1 BT007316 mRNA Translation: AAP35980.1 BC000133 mRNA Translation: AAH00133.1 BC002549 mRNA Translation: AAH02549.1
CCDSⁱ	CCDS4801.1 [P36508-1] CCDS75435.1 [P36508-2]
PIRⁱ	A44256
RefSeqⁱ	NP_001278961.1, NM_001292032.1 [P36508-2] NP_003418.2, NM_003427.4 [P36508-1] XP_016866738.1, XM_017011249.1 [P36508-1]
UniGeneⁱ	Hs.388024

3D structure databases

ProteinModelPortalⁱ	P36508
SMRⁱ	P36508
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	113448, 14 interactors
IntActⁱ	P36508, 85 interactors
MINTⁱ	P36508
STRINGⁱ	9606.ENSP00000363064

PTM databases

iPTMnetⁱ	P36508
PhosphoSitePlusⁱ	P36508

Polymorphism and mutation databases

BioMutaⁱ	ZNF76
DMDMⁱ	20455531

Proteomic databases

EPDⁱ	P36508
MaxQBⁱ	P36508
PaxDbⁱ	P36508
PeptideAtlasⁱ	P36508
PRIDEⁱ	P36508
ProteomicsDBⁱ	55204 55205 [P36508-2]

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	7629
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000339411; ENSP00000344097; ENSG00000065029 [P36508-2] ENST00000373953; ENSP00000363064; ENSG00000065029 [P36508-1]
GeneIDⁱ	7629
KEGGⁱ	hsa:7629
UCSCⁱ	uc003oki.2 human [P36508-1]

Organism-specific databases

CTDⁱ	7629
EuPathDBⁱ	HostDB:ENSG00000065029.14
GeneCardsⁱ	ZNF76
HGNCⁱ	HGNC:13149 ZNF76
HPAⁱ	HPA030090 HPA030091
MIMⁱ	194549 gene
neXtProtⁱ	NX_P36508
OpenTargetsⁱ	ENSG00000065029
PharmGKBⁱ	PA37723
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
GeneTreeⁱ	ENSGT00910000144040
HOGENOMⁱ	HOG000118073
HOVERGENⁱ	HBG053078
InParanoidⁱ	P36508
KOⁱ	K20828
OMAⁱ	SMVTQHS
OrthoDBⁱ	EOG091G0N38
PhylomeDBⁱ	P36508
TreeFamⁱ	TF333498

Enzyme and pathway databases

SIGNORⁱ	P36508

SIGNORⁱ

P36508

Miscellaneous databases

ChiTaRSⁱ	ZNF76 human
GeneWikiⁱ	ZNF76
GenomeRNAiⁱ	7629
Protein Ontology More...PROⁱ	PR:P36508
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000065029 Expressed in 206 organ(s), highest expression level in left lobe of thyroid gland
CleanExⁱ	HS_ZNF76
ExpressionAtlasⁱ	P36508 baseline and differential
Genevisibleⁱ	P36508 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
Pfamⁱ	View protein in Pfam PF00096 zf-C2H2, 4 hits
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 7 hits
SUPFAMⁱ	SSF57667 SSF57667, 4 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 7 hits PS50157 ZINC_FINGER_C2H2_2, 7 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	ZNF76_HUMAN
Accessionⁱ	P36508Primary (citable) accession number: P36508 Secondary accession number(s): Q9BQB2
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	June 1, 1994
	Last sequence update:	May 2, 2002
	Last modified:	November 7, 2018
	This is version 175 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
Human chromosome 6
Human chromosome 6: entries, gene names and cross-references to MIM

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UniProtKB - P36508 (ZNF76_HUMAN)

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Zinc finger protein 76

ZNF76

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Nucleus

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Region

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Experimental Info

Natural variant

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ