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UniProtKB - P36325 (VP7_AHSV4)
Protein
Core protein VP7
Gene
Segment-7
Organism
African horse sickness virus 4 (AHSV-4)
Status
Functioni
Major structural core protein; binds to structural protein VP3. Constitutes the surface of the AHSV core.
GO - Molecular functioni
- host cell surface receptor binding Source: InterPro
- structural molecule activity Source: InterPro
GO - Biological processi
- fusion of virus membrane with host plasma membrane Source: InterPro
Names & Taxonomyi
Protein namesi | Recommended name: Core protein VP7Alternative name(s): Capsid protein VP7 VP7 antigen |
Gene namesi | Name:Segment-7 |
Organismi | African horse sickness virus 4 (AHSV-4) |
Taxonomic identifieri | 36421 [NCBI] |
Taxonomic lineagei | Viruses › Riboviria › Orthornavirae › Duplornaviricota › Resentoviricetes › Reovirales › Reoviridae › Sedoreovirinae › Orbivirus › |
Virus hosti | Camelus dromedarius (Dromedary) (Arabian camel) [TaxID: 9838] Canis lupus familiaris (Dog) (Canis familiaris) [TaxID: 9615] Equus asinus (Donkey) (Equus africanus asinus) [TaxID: 9793] Equus burchelli (Plains zebra) (Equus quagga) [TaxID: 9790] Equus caballus (Horse) [TaxID: 9796] Equus hemionus (Onager) (Asian wild ass) [TaxID: 9794] Loxodonta africana (African elephant) [TaxID: 9785] |
Subcellular locationi
- Virion Curated
Keywords - Cellular componenti
Capsid protein, Outer capsid protein, VirionPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000222736 | 1 – 350 | Core protein VP7Add BLAST | 350 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 45 | N-linked (GlcNAc...) asparagine; by hostSequence analysis | 1 |
Keywords - PTMi
GlycoproteinInteractioni
Subunit structurei
Homotrimer.
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P36325 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P36325 |
Family & Domainsi
Sequence similaritiesi
Belongs to the orbivirus VP7 family.Curated
Family and domain databases
Gene3Di | 1.10.170.10, 1 hit 1.10.250.10, 1 hit |
InterProi | View protein in InterPro IPR008980, Capsid_hemagglutn IPR001803, Orbi_VP7_capsid IPR023178, Orbi_VP7_capsid_C IPR023176, Orbi_VP7_capsid_N IPR008935, Virus_capsid_a-hlx_vir |
Pfami | View protein in Pfam PF00897, Orbi_VP7, 1 hit |
PRINTSi | PR00903, VP7CAPSID |
SUPFAMi | SSF48345, SSF48345, 1 hit SSF49818, SSF49818, 1 hit |
i Sequence
Sequence statusi: Complete.
P36325-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDAIAARALS VVRACVTVTD ARVSLDPGVM ETLGIAINRY NGLTNHSVSM
60 70 80 90 100
RPQTQAERNE MFFMCTDMVL AALNVQIGNI SPDYDQALAT VGALATTEIP
110 120 130 140 150
YNVQAMNDIV RITGQMQTFG PSKVQTGPYA GAVEVQQSGR YYVPQGRTRG
160 170 180 190 200
GYINSNIAEV CMDAGAAGQV NALLAPRRGD AVMIYFVWRP LRIFCDPQGA
210 220 230 240 250
SLESAPGTFV TVDGVNVAAG DVVAWNTIAP VNVGNPGARR SILQFEVLWY
260 270 280 290 300
TSLDRSLDTV PELAPTLTRC YAYVSPTWHA LRAVIFQQMN MQPINPPIFP
310 320 330 340 350
PTERNEIVAY LLLVASLADV YAALRPDFRM NGVVAPVGQI NRALVLAAYH
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 207 | G → GAPG (PubMed:1646273).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D12533 Genomic RNA Translation: BAA02096.1 X56676 mRNA Translation: CAA39999.1 |
PIRi | JQ1946 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D12533 Genomic RNA Translation: BAA02096.1 X56676 mRNA Translation: CAA39999.1 |
PIRi | JQ1946 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1AHS | X-ray | 2.30 | A/B/C | 126-251 | [»] | |
SMRi | P36325 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P36325 |
Family and domain databases
Gene3Di | 1.10.170.10, 1 hit 1.10.250.10, 1 hit |
InterProi | View protein in InterPro IPR008980, Capsid_hemagglutn IPR001803, Orbi_VP7_capsid IPR023178, Orbi_VP7_capsid_C IPR023176, Orbi_VP7_capsid_N IPR008935, Virus_capsid_a-hlx_vir |
Pfami | View protein in Pfam PF00897, Orbi_VP7, 1 hit |
PRINTSi | PR00903, VP7CAPSID |
SUPFAMi | SSF48345, SSF48345, 1 hit SSF49818, SSF49818, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | VP7_AHSV4 | |
Accessioni | P36325Primary (citable) accession number: P36325 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 1, 1994 |
Last sequence update: | November 1, 1997 | |
Last modified: | June 2, 2021 | |
This is version 93 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Viral Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structureDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families