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Protein

DNA replication and repair protein RecF

Gene

recF

Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi30 – 37ATPSequence analysis8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processDNA damage, DNA repair, DNA replication, SOS response
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA replication and repair protein RecF
Gene namesi
Name:recF
Ordered Locus Names:SCO3876
ORF Names:SCH18.13c
OrganismiStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Taxonomic identifieri100226 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomycesStreptomyces albidoflavus group
Proteomesi
  • UP000001973 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001964701 – 373DNA replication and repair protein RecFAdd BLAST373

Interactioni

Protein-protein interaction databases

STRINGi100226.SCO3876

Structurei

3D structure databases

ProteinModelPortaliP36176
SMRiP36176
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RecF family.Curated

Phylogenomic databases

eggNOGiENOG4105C3X Bacteria
COG1195 LUCA
HOGENOMiHOG000269561
InParanoidiP36176
KOiK03629
OMAiGQQKSFL
OrthoDBiPOG091H00U7
PhylomeDBiP36176

Family and domain databases

HAMAPiMF_00365 RecF, 1 hit
InterProiView protein in InterPro
IPR001238 DNA-binding_RecF
IPR018078 DNA-binding_RecF_CS
IPR027417 P-loop_NTPase
IPR003395 RecF/RecN/SMC_N
PANTHERiPTHR32182:SF0 PTHR32182:SF0, 1 hit
PfamiView protein in Pfam
PF02463 SMC_N, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00611 recf, 1 hit
PROSITEiView protein in PROSITE
PS00617 RECF_1, 1 hit
PS00618 RECF_2, 1 hit

Sequencei

Sequence statusi: Complete.

P36176-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHVTHLSLAD FRSYARVEVP LDPGVTAFVG PNGQGKTNLV EAVGYLATLG
60 70 80 90 100
SHRVSSDAPL VRMGAERAVI RAQVRQGERQ QLIELELNPG RANRARVNRS
110 120 130 140 150
SQVKPRDVLG IVRTVLFAPE DLALVKGDPG ERRRFLDELI TARSPRMAGV
160 170 180 190 200
RSDYDRVLKQ RNTLLKSAAL ARRHGGRTMD LSTLDVWDQH LARAGAELLA
210 220 230 240 250
QRLDLIASVQ PLADKAYEQL APGGGPVALE YKPSAPGEAH TREDLYEQLM
260 270 280 290 300
AALAEARKQE IERGVTLVGP HRDDLLLKLG SLPAKGYASH GESWSYALAL
310 320 330 340 350
RLASFDLLRA EGNEPVLVLD DVFAELDARR RERLAELVAP GEQVLVTAAV
360 370
DDDVPHVLAG ARFTVAEGTV ERV
Length:373
Mass (Da):40,743
Last modified:June 1, 1994 - v1
Checksum:iC49CF45717F95C84
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L27063 Genomic DNA Translation: AAA65213.1
AL939118 Genomic DNA Translation: CAB92996.1
PIRiT10967
RefSeqiNP_628063.1, NC_003888.3
WP_003975056.1, NC_003888.3

Genome annotation databases

EnsemblBacteriaiCAB92996; CAB92996; CAB92996
GeneIDi1099312
KEGGisco:SCO3876
PATRICifig|100226.15.peg.3949

Entry informationi

Entry nameiRECF_STRCO
AccessioniPrimary (citable) accession number: P36176
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: May 23, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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