UniProtKB - P36036 (YRA2_YEAST)
Protein
RNA annealing protein YRA2
Gene
YRA2
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
Involved in export of poly(A) mRNAs from the nucleus. Recruited to the coding sequences as well as poly-A sites of active genes.2 Publications
Miscellaneous
Present with 1310 molecules/cell in log phase SD medium.1 Publication
GO - Molecular functioni
- DNA binding Source: UniProtKB-KW
- RNA binding Source: SGD
GO - Biological processi
- poly(A)+ mRNA export from nucleus Source: SGD
Keywordsi
Molecular function | DNA-binding, RNA-binding |
Biological process | mRNA transport, Transport |
Protein family/group databases
TCDBi | 3.A.22.1.1, the transcription-coupled trex/tap nuclear mrna export complex (trex) family |
Names & Taxonomyi
Protein namesi | Recommended name: RNA annealing protein YRA2 |
Gene namesi | Name:YRA2 Ordered Locus Names:YKL214C |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
EuPathDBi | FungiDB:YKL214C |
SGDi | S000001697, YRA2 |
Subcellular locationi
Keywords - Cellular componenti
NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000082033 | 1 – 203 | RNA annealing protein YRA2Add BLAST | 203 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 1 | N-acetylmethionineCombined sources | 1 |
Keywords - PTMi
AcetylationProteomic databases
MaxQBi | P36036 |
PaxDbi | P36036 |
PRIDEi | P36036 |
PTM databases
iPTMneti | P36036 |
Interactioni
Subunit structurei
Associates with mRNPs.
Interacts with YRA1.
1 PublicationProtein-protein interaction databases
BioGRIDi | 33951, 278 interactors |
DIPi | DIP-6538N |
IntActi | P36036, 8 interactors |
MINTi | P36036 |
STRINGi | 4932.YKL214C |
Miscellaneous databases
RNActi | P36036, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 64 – 138 | RRMPROSITE-ProRule annotationAdd BLAST | 75 |
Sequence similaritiesi
Belongs to the YRA1 family.Curated
Phylogenomic databases
eggNOGi | ENOG502S444, Eukaryota |
HOGENOMi | CLU_111217_0_0_1 |
InParanoidi | P36036 |
OMAi | KQTAQEH |
Family and domain databases
CDDi | cd12295, RRM_YRA2, 1 hit |
Gene3Di | 3.30.70.330, 1 hit |
InterProi | View protein in InterPro IPR025715, FoP_C IPR012677, Nucleotide-bd_a/b_plait_sf IPR035979, RBD_domain_sf IPR000504, RRM_dom IPR034396, Yra2_RRM |
Pfami | View protein in Pfam PF13865, FoP_duplication, 1 hit PF00076, RRM_1, 1 hit |
SMARTi | View protein in SMART SM00360, RRM, 1 hit |
SUPFAMi | SSF54928, SSF54928, 1 hit |
PROSITEi | View protein in PROSITE PS50102, RRM, 1 hit |
i Sequence
Sequence statusi: Complete.
P36036-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDKAFDEIIG NSHTDSSSNH KVTRYRRRDL RNELGPRLGF APSDAASRSK
60 70 80 90 100
DRLYREREEP PLPKRIRISK IPLDVSDYTL DDMIKEFGSP IFSKIFDNKE
110 120 130 140 150
DRTCIYEFED PEVLEKIVER YNGHELHNAK IEVEIYQPQR KHSRMNAHNR
160 170 180 190 200
RKQTAQEHGR GRPGSHYRQK PNRVSKKNKG REKNNTPTSV EALDAELDAY
MKG
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X75951 Genomic DNA Translation: CAA53559.1 Z28214 Genomic DNA Translation: CAA82059.1 BK006944 Genomic DNA Translation: DAA08955.1 |
PIRi | S38052 |
RefSeqi | NP_012708.1, NM_001179779.1 |
Genome annotation databases
EnsemblFungii | YKL214C_mRNA; YKL214C; YKL214C |
GeneIDi | 853666 |
KEGGi | sce:YKL214C |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X75951 Genomic DNA Translation: CAA53559.1 Z28214 Genomic DNA Translation: CAA82059.1 BK006944 Genomic DNA Translation: DAA08955.1 |
PIRi | S38052 |
RefSeqi | NP_012708.1, NM_001179779.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 33951, 278 interactors |
DIPi | DIP-6538N |
IntActi | P36036, 8 interactors |
MINTi | P36036 |
STRINGi | 4932.YKL214C |
Protein family/group databases
TCDBi | 3.A.22.1.1, the transcription-coupled trex/tap nuclear mrna export complex (trex) family |
PTM databases
iPTMneti | P36036 |
Proteomic databases
MaxQBi | P36036 |
PaxDbi | P36036 |
PRIDEi | P36036 |
Genome annotation databases
EnsemblFungii | YKL214C_mRNA; YKL214C; YKL214C |
GeneIDi | 853666 |
KEGGi | sce:YKL214C |
Organism-specific databases
EuPathDBi | FungiDB:YKL214C |
SGDi | S000001697, YRA2 |
Phylogenomic databases
eggNOGi | ENOG502S444, Eukaryota |
HOGENOMi | CLU_111217_0_0_1 |
InParanoidi | P36036 |
OMAi | KQTAQEH |
Miscellaneous databases
PROi | PR:P36036 |
RNActi | P36036, protein |
Family and domain databases
CDDi | cd12295, RRM_YRA2, 1 hit |
Gene3Di | 3.30.70.330, 1 hit |
InterProi | View protein in InterPro IPR025715, FoP_C IPR012677, Nucleotide-bd_a/b_plait_sf IPR035979, RBD_domain_sf IPR000504, RRM_dom IPR034396, Yra2_RRM |
Pfami | View protein in Pfam PF13865, FoP_duplication, 1 hit PF00076, RRM_1, 1 hit |
SMARTi | View protein in SMART SM00360, RRM, 1 hit |
SUPFAMi | SSF54928, SSF54928, 1 hit |
PROSITEi | View protein in PROSITE PS50102, RRM, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | YRA2_YEAST | |
Accessioni | P36036Primary (citable) accession number: P36036 Secondary accession number(s): D6VWY9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 1, 1994 |
Last sequence update: | June 1, 1994 | |
Last modified: | December 2, 2020 | |
This is version 157 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Yeast chromosome XI
Yeast (Saccharomyces cerevisiae) chromosome XI: entries and gene names - SIMILARITY comments
Index of protein domains and families - Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD