groL3

Functionⁱ

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functionⁱ

ATP binding Source: UniProtKB-KW
protein binding involved in protein folding Source: GO_Central
unfolded protein binding Source: GO_Central

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

'de novo' protein folding Source: GO_Central
chaperone-mediated protein folding Source: GO_Central
protein refolding Source: InterPro

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Chaperone
Ligand	ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCycⁱ	BDIA224911:G1G3J-2079-MONOMER

BioCycⁱ

BDIA224911:G1G3J-2079-MONOMER

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: 60 kDa chaperonin 3UniRule annotation Alternative name(s): GroEL protein 3UniRule annotation Protein Cpn60 3UniRule annotation
Gene namesⁱ	Name:groL3UniRule annotation Synonyms:groEL3UniRule annotation Ordered Locus Names:bll2059
Organismⁱ	Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Taxonomic identifierⁱ	224911 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium › Bradyrhizobium diazoefficiens
Proteomesⁱ	UP000002526 Componentⁱ: Chromosome

Subcellular locationⁱ

Cytoplasm

GO - Cellular componentⁱ

GroEL-GroES complex Source: GO_Central

View the complete GO annotation on QuickGO ...

Keywords - Cellular componentⁱ

Cytoplasm

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Initiator methionineⁱ		Removed1 Publication
ChainⁱPRO_0000063296	2 – 546	60 kDa chaperonin 3Add BLAST		545

Proteomic databases

PRIDEⁱ	P35862

PRIDEⁱ

P35862

Expressionⁱ

Inductionⁱ

By NifA.

Interactionⁱ

Subunit structureⁱ

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

GO - Molecular functionⁱ

protein binding involved in protein folding Source: GO_Central
unfolded protein binding Source: GO_Central

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

STRINGⁱ	224911.bll2059

STRINGⁱ

224911.bll2059

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P35862
SMRⁱ	P35862
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

eggNOGⁱ	ENOG4105CJ9 Bacteria COG0459 LUCA
HOGENOMⁱ	HOG000076290
InParanoidⁱ	P35862
Database of Orthologous Groups More...OrthoDBⁱ	POG091H00E7
PhylomeDBⁱ	P35862

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd03344 GroEL, 1 hit
Gene3Dⁱ	1.10.560.10, 2 hits 3.30.260.10, 2 hits 3.50.7.10, 1 hit
HAMAPⁱ	MF_00600 CH60, 1 hit
InterProⁱ	View protein in InterPro IPR018370 Chaperonin_Cpn60_CS IPR001844 Chaprnin_Cpn60 IPR002423 Cpn60/TCP-1 IPR027409 GroEL-like_apical_dom_sf IPR027413 GROEL-like_equatorial_sf IPR027410 TCP-1-like_intermed_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00118 Cpn60_TCP1, 1 hit
PRINTSⁱ	PR00298 CHAPERONIN60
SUPFAMⁱ	SSF48592 SSF48592, 2 hits SSF52029 SSF52029, 1 hit SSF54849 SSF54849, 1 hit
TIGRFAMsⁱ	TIGR02348 GroEL, 1 hit
PROSITEⁱ	View protein in PROSITE PS00296 CHAPERONINS_CPN60, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

P35862-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSAKEVKFGV NARDRMLRGV DILANAVQVT LGPKGRNVVL DKSFGAPRIT 
        60         70         80         90        100
KDGVAVAKEI ELDDKFENMG AQMVREVASK AADAAGDGTT TATVLAAAIV 
       110        120        130        140        150
REGAKSVAAG MNPMDLKRGI DLAVEAVVAD LQKNSKKVTS NDEIAQVGAI 
       160        170        180        190        200
SANGDQEIGK FLADAVKKVG NEGVITVEEA KSLETELDVV EGMQFDRGYI 
       210        220        230        240        250
SPYFVTNADK MRVEMDDAYI LINEKKLSSL NELLPLLEAV VQTGKPLVIV 
       260        270        280        290        300
AEDVEGEALA TLVVNRLRGG LKVAAVKAPG FGDRRKAMLQ DIAILTGGQA 
       310        320        330        340        350
ISEDLGIKLE NVTLNMLGRA KKVMIDKENT TIVNGAGKKA DIEARVAQIK 
       360        370        380        390        400
AQIEETTSDY DREKLQERLA KLAGGVAVIR VGGATEVEVK ERKDRVDDAM 
       410        420        430        440        450
HATRAAVEEG IVPGGGVALL RASEQLKGLR TENDDQKTGV EIVRKALSWP 
       460        470        480        490        500
ARQIAINAGE DGSIVVGKVL DNEQYSFGFD AQTGEYSNLV SKGIIDPAKV 
       510        520        530        540 
VRIAVQNASS VAGLLITTEA MVAELPKKAT AGPAMPAAPG MGGMDF

Length:546

Mass (Da):57,785

Last modified:January 23, 2007 - v2

Checksum:ⁱD09D4E2F236C87EB

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	Z22603 Genomic DNA Translation: CAA80316.1 AF322013 Genomic DNA Translation: AAG61029.1 BA000040 Genomic DNA Translation: BAC47324.1
PIRⁱ	S35311
NCBI Reference Sequences More...RefSeqⁱ	NP_768699.1, NC_004463.1 WP_011084855.1, NZ_CP011360.1

Genome annotation databases

EnsemblBacteriaⁱ	BAC47324; BAC47324; BAC47324
GeneIDⁱ	1055489
KEGGⁱ	bja:bll2059
PATRICⁱ	fig\|224911.44.peg.1564

Protein	Similar proteins		Species	Score	Length	Source
P35862	Molecular chaperone GroEL		Bradyrhizobium ottawaense		546	UniRef100_P35862
60 kDa chaperonin		Bradyrhizobium japonicum SEMIA 5079		531
60 kDa chaperonin (Fragment)		Bradyrhizobium diazoefficiens		279

Protein	Similar proteins		Species	Score	Length	Source
P35862	60 kDa chaperonin 2		BRADU		550	UniRef90_P35862
60 kDa chaperonin 1		RHOPB		547
60 kDa chaperonin 1		RHOPS		547
60 kDa chaperonin 2		RHOP2		547
60 kDa chaperonin 2		RHOPA		547
+237

Protein	Similar proteins		Species	Score	Length	Source
P35862	60 kDa chaperonin		BARBA		544	UniRef50_P35635
60 kDa chaperonin		BARQU		547
60 kDa chaperonin		BART1		547
60 kDa chaperonin		BARHE		547
60 kDa chaperonin		BARBK		544
+4282

Entry informationⁱ

Entry nameⁱ	CH603_BRADU
Accessionⁱ	P35862Primary (citable) accession number: P35862
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	June 1, 1994
	Last sequence update:	January 23, 2007
	Last modified:	May 23, 2018
	This is version 109 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Prokaryotic Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Direct protein sequencing, Reference proteome

UniProtKB - P35862 (CH603_BRADU)

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60 kDa chaperonin 3

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Enzyme and pathway databases

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Molecule processing

Proteomic databases

Expressionⁱ

Inductionⁱ

Interactionⁱ

Subunit structureⁱ

GO - Molecular functionⁱ

Protein-protein interaction databases

Structureⁱ

3D structure databases

Family & Domainsⁱ

Sequence similaritiesⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProt is an ELIXIR core data resource

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P35862 (CH603_BRADU)

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60 kDa chaperonin 3

groL3

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

UniProt is an ELIXIR core data resource

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ