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Entry version 144 (13 Nov 2019)
Sequence version 2 (27 Sep 2005)
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Protein

Polycomb group protein Psc

Gene

Psc

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. Component of the PcG multiprotein PRC1 complex, a complex that acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-118', rendering chromatin heritably changed in its expressibility. Needed to maintain expression patterns of the homeotic selector genes of the Antennapedia (Antp-C) and Bithorax (BX-C) complexes, and hence for the maintenance of segmental determination.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri263 – 302RING-typePROSITE-ProRule annotationAdd BLAST40

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein, DNA-binding
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DME-2559580 Oxidative Stress Induced Senescence
R-DME-3108214 SUMOylation of DNA damage response and repair proteins
R-DME-3899300 SUMOylation of transcription cofactors
R-DME-4570464 SUMOylation of RNA binding proteins
R-DME-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
R-DME-8943724 Regulation of PTEN gene transcription
R-DME-8953750 Transcriptional Regulation by E2F6

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Polycomb group protein Psc
Alternative name(s):
Protein posterior sex combs
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Psc
ORF Names:CG3886
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0005624 Psc

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000563881 – 1601Polycomb group protein PscAdd BLAST1601

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei656Phosphoserine1 Publication1
Modified residuei658Phosphoserine1 Publication1
Modified residuei1139Phosphoserine1 Publication1
Modified residuei1222Phosphothreonine1 Publication1
Modified residuei1236Phosphothreonine1 Publication1
Modified residuei1251Phosphothreonine1 Publication1
Modified residuei1253Phosphoserine1 Publication1
Modified residuei1266Phosphoserine1 Publication1
Modified residuei1274Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P35820

PRoteomics IDEntifications database

More...
PRIDEi
P35820

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P35820

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0005624 Expressed in 27 organ(s), highest expression level in embryo

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P35820 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P35820 DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of PRC1 complex, which contains many PcG proteins like Pc, ph, Scm, Psc, Sce and also chromatin-remodeling proteins such as histone deacetylases. This complex is distinct from the Esc/E(z) complex, at least composed of esc, E(z), Su(z)12, Rpd3 and Caf1. The 2 complexes however cooperate and interact together during the first 3 hours of development to establish PcG silencing.

2 Publications

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
62201, 42 interactors

Protein interaction database and analysis system

More...
IntActi
P35820, 7 interactors

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0086911

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P35820

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi15 – 155Thr-richAdd BLAST141
Compositional biasi178 – 212Ser-richAdd BLAST35
Compositional biasi565 – 658Ser-richAdd BLAST94
Compositional biasi806 – 878Pro-richAdd BLAST73
Compositional biasi1022 – 1079Gly-richAdd BLAST58
Compositional biasi1170 – 1406Pro-richAdd BLAST237

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri263 – 302RING-typePROSITE-ProRule annotationAdd BLAST40

Keywords - Domaini

Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2660 Eukaryota
ENOG410XPCN LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000173039

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P35820

KEGG Orthology (KO)

More...
KOi
K11459

Identification of Orthologs from Complete Genome Data

More...
OMAi
DTEHLIF

Database of Orthologous Groups

More...
OrthoDBi
1203951at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P35820

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR032443 RAWUL
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
IPR017907 Znf_RING_CS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16207 RAWUL, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00518 ZF_RING_1, 1 hit
PS50089 ZF_RING_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

P35820-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMTPESKAIQ PAAATTKQTA EATATTTMAH TQQKSQLSTL AKTTTTTATN
60 70 80 90 100
KAAKSVVSNA NSSGNNSSKK LALSQSQKTT TTTTPPTTTT TTTAAAAAEA
110 120 130 140 150
TTNADKMQKQ QQLKQQLFAA CSIKVKSENT LATTANAALA AATTTTTTAT
160 170 180 190 200
PALATGKAAK TILENGIKKE STPPAVESVE ASSSSSSSSS SSSSSSSSWP
210 220 230 240 250
TTRRATSEDA SSNGGASADE EKSEEDPTAA VAASSTATTT SDLATTSRPR
260 270 280 290 300
PVLLTAVNPH IICHLCQGYL INATTIVECL HSFCHSCLIN HLRKERFCPR
310 320 330 340 350
CEMVINNAKP NIKSDTTLQA IVYKLVPGLY ERELMRKRAF YKDRPEEAAL
360 370 380 390 400
ATPEQRGDDT EHLIFSPSDD MSLSLEYAEL GELKTDSEPE LVDTLRPRYL
410 420 430 440 450
QCPAMCRVSH LKKFVYDKFE IDAQRFSIDI MYKVKTIVLL DYYTLMDIAY
460 470 480 490 500
IYTWKRDAPM RFYYRVYESP QPLVKPAPRR VLPLKLEKQE RENQEQQLAV
510 520 530 540 550
EVASSKVEPV SLPEDQKAEA SIKVEEQEST REIVKEVIKD VAATPPTETL
560 570 580 590 600
KLVINRNMLD KREKSHSPQM SSKSSSKSSP CTPVSSPSEP NIKLKIDLSK
610 620 630 640 650
QNSVTIIDMS DPERREIVKP LKPEKESRSK KKDKDGSPKS SSSSSSSSSG
660 670 680 690 700
ERKRKSPSPL TVPPLTIRTE RIMSPSGVST LSPRVTSGAF SEDPKSEFLK
710 720 730 740 750
SFALKPIKVK VESPERTLNN RAITPPSPSV QQSASPKSKG NNLDDSILMK
760 770 780 790 800
PPSCMPPKSI ASSKRKSKEP VKAVSKKQKL SPPLPTVDFK IRLPVTNGNS
810 820 830 840 850
SGTASPKIEK PLMPPPAKPP MLAPRKLQPS AQFAPPPSPI HHHAGVQMSA
860 870 880 890 900
PGNRTPIAKR YQPILPKASR PNPFANIPND VNRLLKDAGT EIKSIGGGSV
910 920 930 940 950
ENNSNAAQKP HLYGPKGESK MGPPALPATT PSQGNKNVGK QAGNLPMSAP
960 970 980 990 1000
PNKGNSSNNY LNLALFNSSK CKGKEAPPGC RTPMYTPNSP IYSPSSPQYV
1010 1020 1030 1040 1050
PSYNIPTMPT YKYTPKPTPN SGSGNGGSGS YLQNMLGGGN GGSLGGLFPS
1060 1070 1080 1090 1100
PPTKSDQNTN PAQGGGGSSS ATQSGGNNGI VNNNIYMPNE DAPEKQQVKV
1110 1120 1130 1140 1150
KSLLNSCNIN IPSSLSITIS RDNGDSSSPN NGQHPKHKSP VNNYIEIVKL
1160 1170 1180 1190 1200
PDQPQDQVQA AKEAQKRQSP PAAVPGHLAA KLPPPPPSKA IPSPQHLVSR
1210 1220 1230 1240 1250
MTPPQLPKVA TPPPPSSPRV ITPPKTSPPA NAAKVTPLKP VLTPTQVDKK
1260 1270 1280 1290 1300
TPSPEKRTAA QMGSHSPTAS ENKSPKGGPA GVANSTGGAQ NGDPAAKKFR
1310 1320 1330 1340 1350
PILPRQNGMP ELAPKLPTLA PFVGFNPLQN PAAGKKVPPS KKSPNAGAAA
1360 1370 1380 1390 1400
HQSGQQKLVN GGQSQPAQQK TSPPAQKNQQ QVKKVSKNPT PPPPSLPAVG
1410 1420 1430 1440 1450
KMMPHPVMHS QNAPLSIASS ASAAAVASGQ LDLSNFLKEN LRRVHAAQAA
1460 1470 1480 1490 1500
QAAQVAAAAN QSNMMYNLAQ MGHMTPAMYN YQQAYFREQL SRMQRVGNEV
1510 1520 1530 1540 1550
FNDYLQKLKT AAATGGGGPV EGELKPMLPT VTLPSPGATP PAASPKTSPL
1560 1570 1580 1590 1600
PAGKLTAAAT APQTKGNSSS GAANARQQTA ATGNNGATVP AASLPPATKS

K
Length:1,601
Mass (Da):169,833
Last modified:September 27, 2005 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7C6264A12CDF3D49
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D0Z760D0Z760_DROME
MIP14548p
Psc 49Ea, D-Bmi, Dmel\CG3886, dPSC, l(2)49Ea
1,601Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti23T → TPEAT (PubMed:1833647).Curated1
Sequence conflicti94 – 96AAA → T in CAA41965 (PubMed:1833647).Curated3
Sequence conflicti130T → A in CAA41965 (PubMed:1833647).Curated1
Sequence conflicti136N → T in CAA41965 (PubMed:1833647).Curated1
Sequence conflicti200P → S in CAA41965 (PubMed:1833647).Curated1
Sequence conflicti451I → T in CAA41965 (PubMed:1833647).Curated1
Sequence conflicti513P → A in CAA41965 (PubMed:1833647).Curated1
Sequence conflicti526 – 527EQ → GE in CAA41965 (PubMed:1833647).Curated2
Sequence conflicti570M → L in CAA41965 (PubMed:1833647).Curated1
Sequence conflicti906A → S in CAA41965 (PubMed:1833647).Curated1
Sequence conflicti919S → T in CAA41965 (PubMed:1833647).Curated1
Sequence conflicti969S → N in CAA41965 (PubMed:1833647).Curated1
Sequence conflicti1279P → A in CAA41965 (PubMed:1833647).Curated1
Sequence conflicti1289A → T in CAA41965 (PubMed:1833647).Curated1
Sequence conflicti1364 – 1366SQP → PQS in CAA41965 (PubMed:1833647).Curated3

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X59275 mRNA Translation: CAA41965.1
DQ022542 mRNA Translation: AAZ20646.1
AE013599 Genomic DNA Translation: AAF58434.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S17983

NCBI Reference Sequences

More...
RefSeqi
NP_001286368.1, NM_001299439.1
NP_001286369.1, NM_001299440.1
NP_523725.2, NM_079001.3

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0087798; FBpp0086911; FBgn0005624
FBtr0345196; FBpp0311395; FBgn0005624
FBtr0345375; FBpp0311526; FBgn0005624

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
36431

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG3886

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X59275 mRNA Translation: CAA41965.1
DQ022542 mRNA Translation: AAZ20646.1
AE013599 Genomic DNA Translation: AAF58434.1
PIRiS17983
RefSeqiNP_001286368.1, NM_001299439.1
NP_001286369.1, NM_001299440.1
NP_523725.2, NM_079001.3

3D structure databases

SMRiP35820
ModBaseiSearch...

Protein-protein interaction databases

BioGridi62201, 42 interactors
IntActiP35820, 7 interactors
STRINGi7227.FBpp0086911

PTM databases

iPTMnetiP35820

Proteomic databases

PaxDbiP35820
PRIDEiP35820

Genome annotation databases

EnsemblMetazoaiFBtr0087798; FBpp0086911; FBgn0005624
FBtr0345196; FBpp0311395; FBgn0005624
FBtr0345375; FBpp0311526; FBgn0005624
GeneIDi36431
KEGGidme:Dmel_CG3886

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
100653366
FlyBaseiFBgn0005624 Psc

Phylogenomic databases

eggNOGiKOG2660 Eukaryota
ENOG410XPCN LUCA
GeneTreeiENSGT00940000173039
InParanoidiP35820
KOiK11459
OMAiDTEHLIF
OrthoDBi1203951at2759
PhylomeDBiP35820

Enzyme and pathway databases

ReactomeiR-DME-2559580 Oxidative Stress Induced Senescence
R-DME-3108214 SUMOylation of DNA damage response and repair proteins
R-DME-3899300 SUMOylation of transcription cofactors
R-DME-4570464 SUMOylation of RNA binding proteins
R-DME-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
R-DME-8943724 Regulation of PTEN gene transcription
R-DME-8953750 Transcriptional Regulation by E2F6

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Psc fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
36431

Protein Ontology

More...
PROi
PR:P35820

Gene expression databases

BgeeiFBgn0005624 Expressed in 27 organ(s), highest expression level in embryo
ExpressionAtlasiP35820 baseline and differential
GenevisibleiP35820 DM

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR032443 RAWUL
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
IPR017907 Znf_RING_CS
PfamiView protein in Pfam
PF16207 RAWUL, 1 hit
PROSITEiView protein in PROSITE
PS00518 ZF_RING_1, 1 hit
PS50089 ZF_RING_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPSC_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P35820
Secondary accession number(s): Q9V6I9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: September 27, 2005
Last modified: November 13, 2019
This is version 144 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
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