Polycomb group protein Psc

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• chromatin binding Source: FlyBase <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayⁱ
  • 21177970
• DNA binding Source: FlyBase <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayⁱ
  • 18981224
• zinc ion binding Source: FlyBaseInferred from sequence modelⁱ
  • 21912646

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processⁱ

• axon guidance Source: FlyBase <p>Inferred from Mutant Phenotype</p> <p>Describes annotations that are concluded from looking at variations or changes in a gene product such as mutations or abnormal levels and includes techniques such as knockouts, overexpression, anti-sense experiments and use of specific protein inhibitors.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#imp">GO evidence code guide</a></p> Inferred from mutant phenotypeⁱ
  • 18516287
• chromatin remodeling Source: FlyBase <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayⁱ
  • 11583617
• chromatin silencing Source: FlyBase <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayⁱ
  • 18981224
• syncytial blastoderm mitotic cell cycle Source: FlyBase <p>Inferred from Mutant Phenotype</p> <p>Describes annotations that are concluded from looking at variations or changes in a gene product such as mutations or abnormal levels and includes techniques such as knockouts, overexpression, anti-sense experiments and use of specific protein inhibitors.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#imp">GO evidence code guide</a></p> Inferred from mutant phenotypeⁱ
  • 16388795
• ventral cord development Source: FlyBaseInferred from high throughput mutant phenotypeⁱ
  • 26092715

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsⁱ

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componentⁱ

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingⁱ

Molecule processing

Amino acid modifications

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMⁱ

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressionⁱ

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structureⁱ

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structureⁱ

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Compositional bias

Zinc finger

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MMTPESKAIQ PAAATTKQTA EATATTTMAH TQQKSQLSTL AKTTTTTATN 
        60         70         80         90        100
KAAKSVVSNA NSSGNNSSKK LALSQSQKTT TTTTPPTTTT TTTAAAAAEA 
       110        120        130        140        150
TTNADKMQKQ QQLKQQLFAA CSIKVKSENT LATTANAALA AATTTTTTAT 
       160        170        180        190        200
PALATGKAAK TILENGIKKE STPPAVESVE ASSSSSSSSS SSSSSSSSWP 
       210        220        230        240        250
TTRRATSEDA SSNGGASADE EKSEEDPTAA VAASSTATTT SDLATTSRPR 
       260        270        280        290        300
PVLLTAVNPH IICHLCQGYL INATTIVECL HSFCHSCLIN HLRKERFCPR 
       310        320        330        340        350
CEMVINNAKP NIKSDTTLQA IVYKLVPGLY ERELMRKRAF YKDRPEEAAL 
       360        370        380        390        400
ATPEQRGDDT EHLIFSPSDD MSLSLEYAEL GELKTDSEPE LVDTLRPRYL 
       410        420        430        440        450
QCPAMCRVSH LKKFVYDKFE IDAQRFSIDI MYKVKTIVLL DYYTLMDIAY 
       460        470        480        490        500
IYTWKRDAPM RFYYRVYESP QPLVKPAPRR VLPLKLEKQE RENQEQQLAV 
       510        520        530        540        550
EVASSKVEPV SLPEDQKAEA SIKVEEQEST REIVKEVIKD VAATPPTETL 
       560        570        580        590        600
KLVINRNMLD KREKSHSPQM SSKSSSKSSP CTPVSSPSEP NIKLKIDLSK 
       610        620        630        640        650
QNSVTIIDMS DPERREIVKP LKPEKESRSK KKDKDGSPKS SSSSSSSSSG 
       660        670        680        690        700
ERKRKSPSPL TVPPLTIRTE RIMSPSGVST LSPRVTSGAF SEDPKSEFLK 
       710        720        730        740        750
SFALKPIKVK VESPERTLNN RAITPPSPSV QQSASPKSKG NNLDDSILMK 
       760        770        780        790        800
PPSCMPPKSI ASSKRKSKEP VKAVSKKQKL SPPLPTVDFK IRLPVTNGNS 
       810        820        830        840        850
SGTASPKIEK PLMPPPAKPP MLAPRKLQPS AQFAPPPSPI HHHAGVQMSA 
       860        870        880        890        900
PGNRTPIAKR YQPILPKASR PNPFANIPND VNRLLKDAGT EIKSIGGGSV 
       910        920        930        940        950
ENNSNAAQKP HLYGPKGESK MGPPALPATT PSQGNKNVGK QAGNLPMSAP 
       960        970        980        990       1000
PNKGNSSNNY LNLALFNSSK CKGKEAPPGC RTPMYTPNSP IYSPSSPQYV 
      1010       1020       1030       1040       1050
PSYNIPTMPT YKYTPKPTPN SGSGNGGSGS YLQNMLGGGN GGSLGGLFPS 
      1060       1070       1080       1090       1100
PPTKSDQNTN PAQGGGGSSS ATQSGGNNGI VNNNIYMPNE DAPEKQQVKV 
      1110       1120       1130       1140       1150
KSLLNSCNIN IPSSLSITIS RDNGDSSSPN NGQHPKHKSP VNNYIEIVKL 
      1160       1170       1180       1190       1200
PDQPQDQVQA AKEAQKRQSP PAAVPGHLAA KLPPPPPSKA IPSPQHLVSR 
      1210       1220       1230       1240       1250
MTPPQLPKVA TPPPPSSPRV ITPPKTSPPA NAAKVTPLKP VLTPTQVDKK 
      1260       1270       1280       1290       1300
TPSPEKRTAA QMGSHSPTAS ENKSPKGGPA GVANSTGGAQ NGDPAAKKFR 
      1310       1320       1330       1340       1350
PILPRQNGMP ELAPKLPTLA PFVGFNPLQN PAAGKKVPPS KKSPNAGAAA 
      1360       1370       1380       1390       1400
HQSGQQKLVN GGQSQPAQQK TSPPAQKNQQ QVKKVSKNPT PPPPSLPAVG 
      1410       1420       1430       1440       1450
KMMPHPVMHS QNAPLSIASS ASAAAVASGQ LDLSNFLKEN LRRVHAAQAA 
      1460       1470       1480       1490       1500
QAAQVAAAAN QSNMMYNLAQ MGHMTPAMYN YQQAYFREQL SRMQRVGNEV 
      1510       1520       1530       1540       1550
FNDYLQKLKT AAATGGGGPV EGELKPMLPT VTLPSPGATP PAASPKTSPL 
      1560       1570       1580       1590       1600
PAGKLTAAAT APQTKGNSSS GAANARQQTA ATGNNGATVP AASLPPATKS 

K                                                      

Experimental Info

Sequence databases

Genome annotation databases

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 100% Identity
• 90% Identity
• 50% Identity

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termⁱ

Documents

1. Drosophila
   Drosophila: entries, gene names and cross-references to FlyBase